BackgroundCommunity-associated Clostridioides difficile infections (CA-CDI) have increased worldwide. Patients with CDI-related symptoms occurring 48 hours after hospitalisation and no inpatient stay 12 weeks prior are classified as CA-CDI, regardless of hospital day attendances 3 months …

Clostridioides difficile represents a major burden to public health. As a well-known nosocomial pathogen whose occurrence is highly associated with antibiotic treatment, most examined C. difficile strains originated from clinical specimen and were isolated under selective conditions em …

The regional CDI burden in Asia is still incompletely documented, seemingly due to low awareness and limited laboratory testing. Despite this apparent under recognition, the current CDI burden highlights the need for broader surveillance and for application of preventative measures against CDI in As …

Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea, despite the widespread implementation of contact precautions for patients with CDI. Here, we investigate strain contamination in a hospital setting and the genomic determinants of disease outcomes. Ac …

Clostridioides difficile has become the leading single cause of hospital-acquired infections. Numerous studies have demonstrated the importance of specific metabolic pathways in aspects of C. difficile pathophysiology, from initial colonization to ...

Enhancing cleaning and disinfection practices in healthcare settings could lower the transmission of C diff within hospitals.

Introduction Neonatal diarrhea (ND) is a common occurrence on Canadian pig farms. The cause of neonatal diarrhea in piglets is often multifactorial; many infectious pathogens can contribute to diarrhea. This […]

AN INCREASE in patients contracting infections while staying in Hampshire hospitals in December has been reported, with an investigation launched in…

In our hospital, HO-CDI incidence rate is lower than that in high-income countries. National multicenter surveillance is needed to evaluate the actual burden of CDI in Saudi Arabia.

Nature Genetics - Genomic analysis of 906 Clostridium difficile strains shows that this enteropathogen is undergoing speciation, which is linked to the selection of genes involved in sporulation...

Research indicates that rates of Clostridium difficile infection among those typically not considered at high risk of infection are increasing, and these infections are becoming more frequent, severe, and difficult to treat.

A recent study has examined the connection between hospital beds and increased Clostridioides difficile infections.

Quantifying the outcomes associated with antimicrobial-resistant infections provides valuable information for policymakers and is an essential first step in understanding the total economic impacts of AMR.

A study led by Lucy S. Witt, MD, investigates hospital bed's role in C difficile transmission, emphasizing room interactions and infection prevention.

null

Deadly hospital infections caused by Clostridioides difficile, or C. diff, may not result from transmission after all, researchers report.

Using a life tables approach with 2011-2017 claims data, we calculated lifetime risks of Clostridioides difficile infection (CDI) beginning at age 18 years. The lifetime CDI risk rates were 32% in female patients insured by Medicaid, 10% in commercially insured male patients, and almost 40% i …

Our algorithm accurately detected true HA-CDI cases from EHR data in our patient population. A multi-component algorithm performs better than any isolated component. Requiring a positive laboratory test for C. difficile strengthens diagnostic performance even further. Accurate detection could …

There was a high incidence of outpatient CDI despite infrequent CDI testing among patients with MAD. The majority of those with outpatient CDI had no recent antibiotic use and no recent hospitalization. Further studies are needed to understand the source and management of medically attended outpatie …

A study conducted at various hospitals in California suggests that outpatient Clostridioides difficile infection (CDI) may be underdiagnosed. Read more about the demographics, risk factors, and implications of this underdiagnosis.

California hospitals detected a high incidence of Clostridioides difficile infection among outpatients treated for diarrhea despite a low rate of testing, suggesting that outpatient C. difficile may be underdiagnosed, researchers said.

A new study looked at Clostridioides difficile infection (CDI) in outpatient settings and found the bacteria may be underdiagnosed, according to a study out Jan. 11 in Open Forum Infectious Diseases.

Antimicrobial-resistant organisms remain a serious threat to public health in Canada. The results of this survey warrant further investigation into AROs in smaller Canadian hospitals as a potential reservoir of antimicrobial resistance.

The performance of our models after weighting did not change drastically suggesting that our model predicting C. difficile infection, severity, and recurrence may not be impacted by patient selection factors; however, other researchers may want to consider addressing these catchment forces using IPW …

A study of two large, integrated health systems found a high incidence of outpatient CDI, despite limited testing of patients with diarrhea.

Clostridioides difficile infection (CDI) is the main source of healthcare and antibiotic-associated diarrhea in hospital context and long-term care units, showing significant morbidity and mortality. This study aimed to analyze the epidemiological context, describing the severity and outcomes …

Learn about the hidden threat in hospital beds with Clostridioides Difficile, its risks and infection prevention measures. Find out more about C. difficile and its impact on patient health.

Staying in a hospital room or bed previously occupied by someone with Clostridioides difficile nearly doubles a patient’s risk for hospital onset-C. difficile infection, researchers found.

Clostridioides difficile is a Gram-positive, anaerobic, and spore-forming bacterial member of the human gut microbiome. The primary virulence factors of C. difficile are toxin A and toxin B. These toxins damage the cell cytoskeleton and cause various diseases, from diarrhea to severe pseudomembranou …