C Diff Transmission

spaniClostridioides difficile/i is a significant cause of diarrhea worldwide, initially as a hospital-acquired infection and, more recently, as a community-associated infection. Risk factors for hospital-acquired iC. difficile/i infection include antimicrobial consumption, extended hospitalizati/span …

Clostridioides difficile is a significant cause of diarrhea worldwide, initially as a hospital-acquired infection and, more recently, as a community-associated infection. Risk factors for hospital-acquired C. difficile infection include antimicrobial consumption, extended hospitalizati …

Clostridioides difficile is the predominant pathogen in hospital-acquired infections and antibiotic-associated diarrhea. Dedicated networks and annual reports for C. difficile surveillance have been established in Europe and North America, however the extensive investigation on the prevalence of C. difficile infection (CDI) in China is limited. In this study, 1528 patients with diarrhea were recruited from seven geographically representative regions of China between July 2021 and July 2022. The positivity rate of toxigenic C. difficile using real-time fluorescence quantitative PCR test of feces was 10.2% (156/1528), and 125 (8.2%, 125/1528) strains were successfully isolated. The isolates from different geographical areas had divergent characteristics after multilocus sequence typing, toxin gene profiling, and antimicrobial susceptibility testing. No isolate from clade 2 were found, and clade 1 was still the main clade for these clinical isolates. Interestingly, clade 4, especially ST37, previously known as the characteristic type of China, showed a strong geographical divergence. Clade 3, although rare in China, has been detected in Hainan and Sichuan provinces. Most C. difficile isolates (76.8%, 96/125) were toxigenic. Clindamycin, erythromycin, and moxifloxacin were the top three antibiotics to which resistance was observed, with resistance rates of 81.3%, 63.6%, and 24.0%, respectively. Furthermore, 34 (27.2%, 34/125) multidrug-resistant (MDR) strains were identified. All the strains were sensitive to metronidazole, vancomycin, and meropenem. The genotype of C. difficile varies greatly among the different geographical regions in China, and new types are constantly emerging. Therefore, comprehensive, longitudinal, and standardized surveillance of C. difficile infections is needed in China, covering typical geographical areas.

German surveillance data from 2022 reported a prevalence of nosocomial infections among hospitalized patients of 5,2%. Clostridioides-difficile-infections (CDI) are the most frequent cause of nosocomial diarrhea. They are usually caused by antibiotic exposure and the subsequent changes in the gut mi …

Compared to Illumina, Nanopore has higher error rate, which limits its application for high-resolution epidemiological surveillance. However, the short analysis time, lower cost and more simple procedure combined with correctly identified STs and virulence genes, makes it an alternative when fast an …

German surveillance data from 2022 reported a prevalence of nosocomial infections among hospitalized patients of 5,2%. Clostridioides-difficile-infections (CDI) are the most frequent cause of nosocomial diarrhea. They are usually caused by antibiotic exposure and the subsequent changes in the gut mi …

Results suggest possible association between specific room features and HO-CDI, which could be further investigated with techniques like environmental sampling. Moreover, findings from the study offer valuable insights for targeted intervention measures.

Results suggest possible association between specific room features and HO-CDI, which could be further investigated with techniques like environmental sampling. Moreover, findings from the study offer valuable insights for targeted intervention measures.

spanbiIntroduction:/i/b Alcohol is the most frequently abused drug in the United States, and alcohol use disorder (AUD) is a common comorbidity in intensive care units (ICUs). biPatients and Methods:/i/b We performed a retrospective chart review of patients admitted to an ICU between Jan/span …

The global burden of CDI has significantly increased, particularly in regions with high SDI and among individuals aged 70 years and above. During the COVID-19 pandemic period from 2020 to 2021, the burden of CDI further increased in regions with low, low-middle, and middle SDI. These findings unders …

Prevention of CDI among adults 18-64 years old may significantly reduce costs and mortality.

This study highlights the significant impact of CDI infections on health outcomes for leukemia patients, emphasizing the need for robust infection control measures, early detection, and aggressive management of CDI to improve patient outcomes and minimize healthcare costs.

BackgroundClostridioides difficile infection (CDI) is a severe infection that needs to be monitored. This infection predominantly occurs in hospitalised patients after antimicrobial treatment, with high mortality in elderly patients.AimWe aimed at estimating the incidence of CDI in Italian ho …

Background iClostridium difficile/i infection (CDI) is a significant healthcare concern, marked by its rising prevalence and associated morbidity and mortality. However, there is limited data on the epidemiology of CDI in the eastern region of India. Objectives The study aims to determine the in …

PDF | Clostridium difficle anaerobic toxin producing bacilli is now an emerging enteric causing Nosocomial infection. Most common leading cause of... | Find, read and cite all the research you need on ResearchGate

Using the latest data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), the GBD 2021 Diarrhoeal Diseases Collaborators1 have published updated estimates of the global diarrhoeal disease burden in The Lancet Infectious Diseases. This study used a thorough methodology to provide new, timely, and crucial evidence to support the global strategy for diarrhoeal disease prevention and control.

Cases of C difficile caught in hospital are up a quarter on last year, according to recent figures seen by HSJ.

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C. difficile ST81 is among the common STs in this study. Two independent sub-lineages of C. difficile ST81 strains are found. Furthermore, the presence of a high number of AMR genes and multiple mobile elements indicate a potential risk for transmission of C. difficile ST81. Bas …

The objective of this study was to determine the presence of C. difficile in seafood, to identify the ribotype of isolates, to reveal the distribution of their toxinogenic genes and to evaluate the antibiotic susceptibility of C. difficile strains. For this purpose, a total of 755 seafood samples we …

The objective of this study was to determine the presence of C. difficile in seafood, to identify the ribotype of isolates, to reveal the distribution of their toxinogenic genes and to evaluate the antibiotic susceptibility of C. difficile strains. For this purpose, a total of 755 seafood samples we …

Background Clostridium difficile infection (CDI) is a significant healthcare concern, marked by its rising prevalence and associated morbidity and mortality. However, there is limited data on...

The global antibiotic resistance market is anticipated to reach US$ 17.23 billion by 2030; growing at a CAGR of 7.1% during the forecast period, 2022 – 2030.

The prevalence of C. difficile in spinach, carrot, and milk samples from selected regions was low, and nontoxigenic strains were prevalent. Despite the low prevalence, the detection of C. difficile in these foods highlights the potential risk of foodborne transmission of this pathogen and underscore …

The intricate relationship between human and pet microbiomes represents a fascinating and highly relevant area of study for veterinary professionals.

Clostridioides difficile is one of the leading causes of antibiotic-associated diarrhea. In this study, we characterized 76C. difficile isolates, obtained from three Mediterranean mussel (Mytilus galloprovincialis) farms in Slovenia from November 2014 to October 2015 (sampling period 1) and from Jan …

A bacterial infection is seeing a “significant rise” in Wirral that can lead to “debilitating” diarrhoea as health officials warned the situation was unacceptable as it becomes “business as

The NHS said some people could be more likely to get an infection for six reasons