C Diff Transmission

Toxin-producing Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea. However, it is now recognized as a cause of diarrhea in the community. This single-center study aimed to determine the epidemiological origin of CDI cases between January 2014 and December 20 …

Clostridioides difficile is a human pathogen that is ubiquitous in soil. Despite increasing infection rates and evidence of foodborne transmission, there is limited data on prevalence in soil or which factors influence persistence. The aim of this study was to investigate the prevalence of these bac …

Environmental sources of C. difficile are important to consider in the epidemiology of CDI in Vietnam, however, contaminated soils are likely to be the most important source of C. difficile. This poses additional challenges to controlling infections in healthcare settings.

Researchers evaluated patterns of antibiotic resistance among patients hospitalized with COVID-19 and bacterial coinfections.

Clostridioides difficile is a human pathogen that is ubiquitous in soil. Despite increasing infection rates and evidence of foodborne transmission, there is limited data on prevalence in soil or which factors influence persistence. The aim of this study was to investigate the prevalence of these bac …

In this retrospective cohort from three Missouri hospitals from January 2017 to August 2020, hospital-onset Clostridioides difficile infections (CDI) were more common during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic at the tertiary care hospital. Risk factors associated with hospital-onset CDI included year of hospitalization, age, high-risk antibiotic use, acid-reducing medications, chronic comorbidities, and SARS-CoV-2 infection.

Although it is the so-called hypervirulent epidemic strain, ribotyping 027 (ST1), was not detected. ST3 and ST54 can be transmitted through different hospitals. Therefore, it is necessary to conduct further molecular epidemiological monitoring of C. difficile and screening of patients admitte …

The purpose of this review is to highlight important changes since the 2014 Compendium.

In this retrospective cohort from three Missouri hospitals from January 2017 to August 2020, hospital-onset Clostridioides difficile infections (CDI) were more common during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic at the tertiary care hospital. Risk factors associat …

In Greece, the stark increase in Clostridioides difficile (C. diff) incidence cannot be explained by a rise of antimicrobial use during the pandemic.

Background and Objectives: Colitis with Clostridium difficile is an important health problem that occurs with an intensity that varies between mild and severe. Surgical interventions are required only in fulminant forms. There is little evidence regarding the best surgical intervention …

The prevalence of C. difficile in adults with diarrhoea and multidrug resistance in C. difficile isolates was relatively high. A clinical assessment to differentiate between CDI/disease and colonisation is required.

Most often, the first place a patient enters a hospital is through the emergency department and sometimes by emergency medical services. Where else to better stop Clostridioides difficile from coming into the hospital than at the entrance?

Every year, thousands of patients across the United States are impacted by the effects of hospital-onset Clostridioides difficile (C. diff) infections (HO-CDIs). In this webinar, we examine the limitations of current interventions to prevent transmission of C. diff. We also present the manner in which an effective environmental hygiene program to reduce HO-CDI is implemented and the critical role EVS personnel played. (Webinar presented May 18, 2023)

Antibiotic resistance (AR) and multidrug resistance (MDR) have been confirmed for all major foodborne pathogens: Campylobacter spp., Salmonella spp., Escherichia coli and Listeria monocytogenes. Of great concern to scientists and physicians are also reports of antibiotic- …

Background and Objectives: Colitis with Clostridium difficile is an important health problem that occurs with an intensity that varies between mild and severe. Surgical interventions are required only in fulminant forms. There is little evidence regarding the best surgical intervention …

Clostridioides difficile infection (CDI) is a significant cause of morbidity and mortality, mostly in frail patients. Notification is not mandatory in Italy, and data on incidence, risk of death, and recurrence are lacking. The purpose of this study was to determine CDI incidence and risk fac …

To grasp the epidemiological trend and drug resistance mechanisms of Clostridioides difficile (C. diff) in Beijing, 302 C. diff isolates were obtained from patients with diarrhea. The sequence types (STs) from mainstream strains were all susceptible to metronidazole, vancomycin, piperacillin/tazobac …

The incidence of Clostridioides difficile infection (CDI) has been increasing compared to pre-COVID-19 pandemic levels. The COVID-19 infection and CDI relationship can be affected by gut dysbiosis and poor antibiotic stewardship. As the COVID-19 pandemic transitions into an endemic stage, it …

The interrupted time-series resulted in an increase in C. difficile infection incidences during the pre-pandemic period from 0.00 to 3.36 infections per 10,000 bed days during the COVID-19 pandemic.

C. diff, an infectious disease can be deadly for many – but especially those with compromised immune systems. We speak with a member of the Patients Risi…

Renal insufficiency and metronidazole treatment were independent risk factors for recurrent HCF-CDI in our setting. The relationship between cefotaxime exposure and risk for recurrent HCF-CDI, dose-dependent, could be evaluated further in a setting with high cefotaxime use.

#Cdiff is usually considered a hospital-acquired infection, but recent studies suggest that up to 41% of infections may be community acquired. pic.twitter.com/JaSTUWxAuF— Microbiome Science (@MbiomeScience) May 19, 2023

Introduction. C. difficile infection (CDI) represents an important global threat. In the COVID-19 era, the multifactorial nature of CDI has emerged.Hypothesis - Aim. The aim was to assess the impact of COVID-19 pandemic on the incidence of CDI in a Greek hospital.Methodology. …

Introduction Clostridioides difficile (C. difficile) colonizes the large intestine, rendering healthy individuals asymptomatic carriers of the disease. In certain instances, C. difficile infection (CDI) occurs. Antibiotic use remains the leading risk factor for CDI. During the coronavi …

Introduction. C. difficile infection (CDI) represents an important global threat. In the COVID-19 era, the multifactorial nature of CDI has emerged.Hypothesis - Aim. The aim was to assess the impact of COVID-19 pandemic on the incidence of CDI in a Greek hospital.Methodology. …

Incredibly proud of @Nikki_Winchestr for leading our work on community-associated CDI and presenting 2 posters #SGIM23 and winning a travel award! Outstanding work by a medical student! #Cdiff @Yellowbird44Amy @CleClinicLCM pic.twitter.com/6o8fizDQjc— Abhishek Deshpande (@abhishek_dp) May 12, 2023

Findings show an association between the work environment of nurses and hospital-onset CDI. A promising strategy to lower hospital-onset CDI and other infections is a serious and sustained commitment by hospital leaders to significantly improve nurse work environments.

Clostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibio …

Hospital coding of CDI and notification to authorities has approximately halved from 2015 to 2021. Potential influential factors include hospital hygiene campaigns, implementation of antibiotic stewardship programs, social distancing due to the COVID-19 pandemic, and a decrease in more pathogenic su …