Clostridium difficile colitis following geriatric hip fracture surgery: incidence, trends, and risk factors from 45,910 patients - PubMed
Clostridium difficile colitis is a serious infection after hip fracture surgery in geriatric patients with an incidence of about 1%. Patients at increased risk should be targeted with preventative measures to prevent the morbidity from this complication.
Graph convolutional network-based fusion model to predict risk of hospital acquired infections - PubMed
The proposed model could allow prevention or earlier detection of HAI, which in turn could decrease hospital LoS and associated mortality, and ultimately reduce the healthcare cost.
Clostridioides difficile in food and food products of animal origin in Assam, India - PubMed
Meat, meat products and dry fish, but not milk and milk products were contaminated with C. difficile. Contamination rates were low with diverse toxin profiles and antibiotic resistance patterns among the C. difficile strains.
Old Age, Functional Status Linked to CDI Risk Following Hip Fracture Surgery
Increased age, male sex, COPD, CHF, dependent functional status, and C. difficile infection were associated with increased mortality within 30 days of surgery.
The infectious form of #Cdiff spores are ubiquitous in the environment. #GITwitter #IDtwitter #guthealth #MicrobiomeMonday pic.twitter.com/LvHnZfTkce— Microbiome Science (@MbiomeScience) April 3, 2023
Assessing Acquired Infections Through Medical Transports - Fire Engineering: Firefighter Training and Fire Service News, Rescue
Katherine H. West looks at multiple studies of the facts and dangers of the multitude of microscopic organisms found in medical transports from a lack of cleanliness or proper hygiene.
Pediatric diarrhea patients living in urban areas have a higher incidence of Clostridioides difficile infection - PubMed
Clostridioides difficile infection (CDI) is a major cause of antibiotic-associated diarrhea and an unappreciated contributor to child mortality in low- and middle-income countries where the diagnosis may be difficult. There is little information about the prevalence of CDI among infants, children, a …
A novel, integrated approach for understanding and investigating Healthcare Associated Infections: A risk factors constellation analysis - PubMed
The increasing availability of health data stored in EHRs represents a unique opportunity for the accurate identification of any factor that contributes to the diffusion of HAIs and AMR and for the prompt implementation of effective corrective measures. That said, artificial intelligence might be th …
Pediatric diarrhea patients living in urban areas have a higher incidence of Clostridioides difficile infection - PubMed
Clostridioides difficile infection (CDI) is a major cause of antibiotic-associated diarrhea and an unappreciated contributor to child mortality in low- and middle-income countries where the diagnosis may be difficult. There is little information about the prevalence of CDI among infants, children, a …
C. difficile infection: A close-up on an urgent public health threat
As hospitals have dealt with surging admissions and extended stays with COVID-19, staff and patients alike have still had to contend with another potentially deadly infection from a bacterium called Clostridioides difficile.
Genomic epidemiology and transmission dynamics of recurrent Clostridioides difficile infection in Western Australia - PubMed
Recurrent cases of Clostridioides difficile infection (rCDI) remain one of the most common and serious challenges faced in the management of CDI. The accurate distinction between a relapse (caused by infection with the same strain) and reinfection (caused by a new strain) has implications for infect …
Genomic epidemiology and transmission dynamics of recurrent Clostridioides difficile infection in Western Australia - PubMed
Recurrent cases of Clostridioides difficile infection (rCDI) remain one of the most common and serious challenges faced in the management of CDI. The accurate distinction between a relapse (caused by infection with the same strain) and reinfection (caused by a new strain) has implications for infect …
Aetiology of hospital-acquired diarrhoea in under-five children from an urban hospital in East Delhi, India - PubMed
The findings of this study suggest that the aetiological profile of hospital-acquired diarrhoea appears to be similar to that of community-acquired diarrhoea, with DEC and Cryptosporidium being the most common causes. The efforts for the prevention and management of hospital-acquired diarrhoea shoul …
A case-control study of Clostridioides difficile symptomatic infections in a pediatric cancer hospital - PubMed
C. difficile symptomatic infection in children with cancer was associated with previous hospitalization and the use of common antibiotics in cancer patients, such as vancomycin, meropenem, and cefepime, in the last 3 months. Chemotherapy drugs, such as carboplatin, melphalan, busulfan, and asparagin …
A case-control study of Clostridioides difficile symptomatic infections in a pediatric cancer hospital - PubMed
C. difficile symptomatic infection in children with cancer was associated with previous hospitalization and the use of common antibiotics in cancer patients, such as vancomycin, meropenem, and cefepime, in the last 3 months. Chemotherapy drugs, such as carboplatin, melphalan, busulfan, and asparagin …
Random variation drives a critical bias in the comparison of healthcare-associated infections - PubMed
SIRs and numbers of HAIs are strongly influenced by random effects of volume. Mitigating these effects drastically alters rankings for HAI types and may further alter penalty assignments in programs that aim to reduce HAIs and improve quality of care.
Prevalence and Molecular Characterization of Clostridioides difficile Infection in China Over the Past Five Years: A Systematic Review and Meta-analysis - PubMed
Based on our findings, increased awareness and management of CDI is necessary to reduce the prevalence of CDI in China.
The effect of cold storage and cooking on the viability of Clostridioides difficile spores in consumer foods - PubMed
The increased detection of clinical cases of Clostridioides difficile coupled with the persistence of clostridial spores at various stages along the food chain suggest that this pathogen may be foodborne. This study examined C. difficile (ribotypes 078 and 126) spore viability in chicken breast, bee …
The Environment, Farm Animals and Foods as Sources of Clostridioides difficile Infection in Humans - PubMed
The recent discovery of the same Clostridioides difficile ribotypes associated with human infection in a broad range of environments, animals and foods, coupled with an ever-increasing rate of community-acquired infections, suggests this pathogen may be foodborne. The objective of this review …
Natural history of Clostridioides difficile colonization and infection following new acquisition of carriage in healthcare settings: A prospective cohort study - PubMed
In 3 healthcare facilities, 9.9% of patients acquired asymptomatic carriage of toxigenic C. difficile, and 13.4% were subsequently diagnosed with CDI. Most carriers had transient rather than persistent carriage and most patients developing CDI did not have prior detection of carriage.