MRSA and C difficile in a Children’s Hospital: Finding the Source
Eradicating pathogens on both the floors throughout the hospital, especially patients’ rooms, and within the NICU isolettes is the focus of 2 posters presented at APIC 2022.
A Rare Case of New-Onset Ulcerative Colitis in a Nonagenarian
Ulcerative colitis (UC) is one of two major types of inflammatory bowel disease (IBD). It is defined as a chronic idiopathic inflammatory disease limited to the colorectal mucosal layer and char...
I ended up going to the hospital in January 2021 for abdominal pain on the left side of my belly. First, I went to immediate care and was diagnosed through an x-ray showing that the stool was stuck. I went to Target and grabbed some stool softener which didn’t resolve …
Hypervirulent Clostridioides difficile RT078 lineage isolates from the river: A potential reservoir for environmental transmission - PubMed
This is the first report to discover Clostridiodes difficile (C. difficile) ribotype RT126 and RT598 (both ribotypes belong to RT078-lineage) in a river water system in southern Taiwan. Fluoroquinolone resistance was also found. The connection between clinical isolates and those from the environment …
US government wants to hide hospital safety scores during COVID
The last time Medicare rated hospitals on surgical complications such as bed sores, collapsed lungs, bloodstream infections, and broken hips, four Philadelphia-area facilities scored worse than average.
Quarterly Epidemiological Commentary: Mandatory MRSA, MSSA and Gram-negative bacteraemia and Clostridioides difficile infection, data up to October to December 2022
Epidemiological analyses of mandatory surveillance data on healthcare associated infections (HCAI); MRSA, MSSA and Gram-negative bacteraemia (Escherichia coli (E. coli), Pseudomonas aeruginosa ( P. aeruginoa), Klebsiella species (Klebsiella spp.)), and Clostridioides difficile (C. difficile) infection.
Quarterly Epidemiological Commentary: Mandatory MRSA, MSSA and Gram-negative bacteraemia and Clostridioides difficile infection, data up to April to June 2023
Epidemiological analyses of mandatory surveillance data on healthcare associated infections (HCAI); MRSA, MSSA and Gram-negative bacteraemia (Escherichia coli (E. coli), Pseudomonas aeruginosa ( P. aeruginoa), Klebsiella species (Klebsiella spp.)), and Clostridioides difficile (C. difficile) infection.
Examining Clostridioides difficile Incidence and Clinical Impact Across the US - Contagionlive.com
In a poster presented at MAD-ID 2022, Glenn S. Tillotson, PhD, FIDSA, FCCP, shares data from the Premier Healthcare Database on more than 100,000 patients with C diff.
Predominance of Clostridioides difficile PCR ribotype 181 in northern Greece, 2016-2019
Multiple C. difficile ribotypes have been circulating in the northern Greece region with RTs 181 (closely related to 027), 017, 126 and 078 being predominant.
Development of a Dual-Fluorescent-Reporter System in Clostridioides difficile Reveals a Division of Labor between Virulence and Transmission Gene Expression
The bacterial pathogen Clostridioides difficile causes gastroenteritis by producing toxins and transmits disease by making resistant spores. Toxin and spore production are energy-expensive processes that are regulated by multiple transcription factors in response to many environmental inputs. While …
One-day prevalence of asymptomatic carriage of toxigenic and non-toxigenic Clostridioides difficile in 10 French hospitals
11% of hospitalized patients were asymptomatic carriers of toxigenic or non-toxigenic C. difficile and may constitute a potential reservoir of C. difficile strains.
Incidence, Attributable Mortality, and Healthcare and Out-of-Pocket Costs of Clostridioides difficile Infection in US Medicare Advantage Enrollees
CDI represents an important public health burden in the MAE population. Preventive strategies and treatments are needed to improve outcomes and reduce costs for healthcare systems and this growing population of older US adults.
Isolation of Clostridioides difficile PCR Ribotype 027 from single-use hospital gown ties
Background. Clostridioides difficile is a spore-forming pathogen responsible for antibiotic-associated diarrhoea. In the USA high incidence of C. difficile infection (CDI) in clinical environments has led to interest in C. difficile spore transmission.Hypothesis. S …
Antibiotic-resistant organisms establish reservoirs in new hospital built environments and are related to patient blood infection isolates | Communications Medicine - Nature.com
Communications Medicine - Sukhum, Newcomer et al. evaluate reservoirs of antibiotic-resistant organisms within the built environment and patient samples from an established and a newly-built...
No substantial changes in C. difficile trends early in pandemic - Healio
Despite the changes and disruptions to care caused by COVID-19, researchers found that there were no significant changes in the incidence of Clostridioides difficile during the first year of the pandemic.
“@AvrahamCooperMD Great thread!
Unlike human neonates, piglets develop enteric disease following #Cdiff colonisation (with high mortality). Delay in the onset of colonisation resistance due to atb exposure promotes amplification & spillover of spores into the community. https://t.co/cJrTOidvaG”
C Difficile May Spread Zoonotically Between Pigs and Humans - Contagionlive.com
Antibiotic-resistant strains of the dangerous superbug C difficile have been identified in pigs and humans, suggesting zoonotic transmission is possible.
Notes from the Field: Escherichia coli O157:H7 Outbreak in Children with Clostridioides difficile Colonization Associated with an Improperly Treated Swimming Pool - Pennsylvania, June 2021
On June 7, 2021, the Pennsylvania Department of Health (PADOH) received multiple complaints of gastrointestinal illness from patrons of a community
Examining Clostridioides difficile Incidence and Clinical Impact Across the US
In a poster presented at MAD-ID 2022, Glenn S. Tillotson, PhD, FIDSA, FCCP, shares data from the Premier Healthcare Database on more than 100,000 patients with C diff.
Man v. Microbe: Drug-resistant superbugs gain a toehold in Michigan - Bridge Michigan
The overuse of antibiotics — in ERs, dental offices, and for your steak dinner — means microbes are gaining ground in a microscopic arms race. Next time you ask for antibiotics, your doctor may say “no.”
Trends in facility-level rates of Clostridioides difficile infections in US hospitals, 2019-2020
While there was a slight downward trajectory in CDI trends prior to March 2020, no significant change in CDI trends occurred during the COVID-19 pandemic despite changes in infection control practices, antibiotic use, and healthcare delivery.
A powerful superbug can cross-contaminate between pigs and humans - Interesting Engineering
A recent study on Clostridioides difficile superbug has revealed that antibiotic-resistant bugs can transmit from pigs to humans. The study was presented at the European Congress of Clinical Microbiology & Infectious Diseases.
Fred Gaschen is showing us results from a study from a residency project regarding the effect of #FMT faecal microbiota transplantation 💩💩💩 in healthy #cats 🐈 given #antibiotics. (after giving an introduction in Italian?) 🤷🏼♀️😁
Fred Gaschen is showing us results from a study from a residency project regarding the effect of #FMT faecal microbiota transplantation 💩💩💩 in healthy #cats 🐈 given #antibiotics. (after giving an introduction in Italian?) 🤷🏼♀️😁 Multo bene! pic.twitter.com/YeWfjeUw2b— European Society of Comparative Gastroenterology (@ESCG_ecvim) May 15, 2022
#EuroGut22 is taking off with Melanie Werner giving us an update on #Cdiff in #dogs and a possible #association with dysbiosis index #DI. #GITwitter #gastroenterology #veterinary #science #microbiology #microbiome
#EuroGut22 is taking off with Melanie Werner giving us an update on #Cdiff in #dogs and a possible #association with dysbiosis index #DI. #GITwitter #gastroenterology #veterinary #science #microbiology #microbiome pic.twitter.com/tFpqGf4236— European Society of Comparative Gastroenterology (@ESCG_ecvim) May 14, 2022