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Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile | Future Microbiology
Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile | Future Microbiology
Aim: The objective of this study was to determine the effect of standard and candidate prebiotics on the adhesion and biofilm formation of Bacteroides sp. in monoculture and co-culture with Clostridioides difficile. Materials & methods: The effect of seven prebiotics on the adhesion and biofilm formation of Bacteroides sp. to three human cell lines was determined. The effect of Bacteroides sp. and fructooligosaccharides (FOS) on the adhesion and biofilm formation of C. difficile was tested by the co-incubation assay. Results: Inulin, mannose and raffinose presented the best anti-adhesion properties against Bacteroides sp. Combination of Bacteroides sp. with FOS decreased the adhesion of C. difficile. Conclusion: The study shows the potential role of prebiotics and synbiotics in decreasing the burden of C. difficile infections.
·futuremedicine.com·
Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile | Future Microbiology
Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile
Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile
Aim: The objective of this study was to determine the effect of standard and candidate prebiotics on the adhesion and biofilm formation of Bacteroides sp. in monoculture and co-culture with Clostridioides difficile. Materials & methods: The effect of seven prebiotics …
·pubmed.ncbi.nlm.nih.gov·
Effect of prebiotics on Bacteroides sp. adhesion and biofilm formation and synbiotic effect on Clostridioides difficile
Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water
Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water
Clostridioides difficile infection (CDI) is frequently associated with intestinal injury and mucosal barrier dysfunction, leading to an inflammatory response involving neutrophil localization and upregulation of pro-inflammatory cytokines. The severity of clinical manifestations is associated …
·pubmed.ncbi.nlm.nih.gov·
Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water
Lactobacillus casei Zhang exerts probiotic effects to antibiotic-treated rats
Lactobacillus casei Zhang exerts probiotic effects to antibiotic-treated rats
Probiotics administration can facilitate the restoration of host gut microbiota/metabolome after antibiotic treatment. Yet, the mechanism behind such beneficial effects remains unclear. This study constructed a rat model of antibiotic-induced gut dysbiosis to monitor the effects and mechanism of pro …
·pubmed.ncbi.nlm.nih.gov·
Lactobacillus casei Zhang exerts probiotic effects to antibiotic-treated rats
Evaluation of the therapeutic effect and dose-effect of Bifidobacterium breve on the primary Clostridioides difficile infected mice
Evaluation of the therapeutic effect and dose-effect of Bifidobacterium breve on the primary Clostridioides difficile infected mice
Probiotics are widely used as an adjuvant agent for the prevention of primary Clostridioides difficile infection (pCDI) and are less commonly used in the treatment of pCDI. Here, the different doses of Bifidobacterium breve YH68 were used to treat the pCDI mouse model and the actual therapeutic effe …
·pubmed.ncbi.nlm.nih.gov·
Evaluation of the therapeutic effect and dose-effect of Bifidobacterium breve on the primary Clostridioides difficile infected mice
In vitro and in vivo anti- Clostridioides difficile effect of a probiotic Bacillus amyloliquefaciens strain
In vitro and in vivo anti- Clostridioides difficile effect of a probiotic Bacillus amyloliquefaciens strain
Clostridioides difficile infection (CDI) is a significant cause of hospital-acquired and antibiotic-mediated intestinal diseases and is a growing global public health concern. Overuse of antibiotics and their effect on normal intestinal flora has increased the incidence and severity of infections. T …
·pubmed.ncbi.nlm.nih.gov·
In vitro and in vivo anti- Clostridioides difficile effect of a probiotic Bacillus amyloliquefaciens strain
Next-generation prebiotic promotes selective growth of beneficial bacteria Paving the way for new treatments for refractory clostridioides difficile colitis - The Japan Times
Next-generation prebiotic promotes selective growth of beneficial bacteria Paving the way for new treatments for refractory clostridioides difficile colitis - The Japan Times
The research team comprised of Shin Kurihara, Associate Professor of Department of Science and Technology on Food Safety, Faculty of Biology-Oriented Science and Technology, Kindai University (Kinokawa, Wakayama); Hiroyuki Nakai, Associate Professor of Food Science Program, Faculty of Agriculture, Department of Applied Biological Chemistry, Niigata University (Niigata, Japan); Rika Hirano, a graduate program research student …
·japantimes.co.jp·
Next-generation prebiotic promotes selective growth of beneficial bacteria Paving the way for new treatments for refractory clostridioides difficile colitis - The Japan Times
Incidence of Saccharomyces cerevisiae Fungemia in Hospitalized Patients Administered Saccharomyces boulardii Probiotic
Incidence of Saccharomyces cerevisiae Fungemia in Hospitalized Patients Administered Saccharomyces boulardii Probiotic
Risk of bloodstream infection as a result of S. boulardii probiotic use appears restricted to S. boulardii recipients. Risk for probiotic-related bloodstream infection does not appear greater than the risk of any hospital-acquired bloodstream infection both inside and outside of the intensive care u …
·pubmed.ncbi.nlm.nih.gov·
Incidence of Saccharomyces cerevisiae Fungemia in Hospitalized Patients Administered Saccharomyces boulardii Probiotic
Next-generation prebiotic promotes selective growth of bifidobacteria, suppressing Clostridioides difficile
Next-generation prebiotic promotes selective growth of bifidobacteria, suppressing Clostridioides difficile
Certain existing prebiotics meant to facilitate the growth of beneficial bacteria in the intestine also promote the growth of other prominent bacteria. Therefore, the growth-promoting effects of β-galactosides on intestinal bacteria were analyzed. Galactosyl-β1,4-l-rhamnose (Gal-β1,4-Rha) selectivel …
·pubmed.ncbi.nlm.nih.gov·
Next-generation prebiotic promotes selective growth of bifidobacteria, suppressing Clostridioides difficile
A study into the effect of Lactobacillus casei Shirota in preventing antibiotic associated diarrhoea including Clostridioides difficile infection in patients with spinal cord injuries: a multicentre randomised, double-blind, placebo-controlled trial
A study into the effect of Lactobacillus casei Shirota in preventing antibiotic associated diarrhoea including Clostridioides difficile infection in patients with spinal cord injuries: a multicentre randomised, double-blind, placebo-controlled trial
Yakult Honsha Co., Ltd.
·pubmed.ncbi.nlm.nih.gov·
A study into the effect of Lactobacillus casei Shirota in preventing antibiotic associated diarrhoea including Clostridioides difficile infection in patients with spinal cord injuries: a multicentre randomised, double-blind, placebo-controlled trial
Probiotic-containing yogurt protects against microbiome changes that lead to antibiotic-induced diarrhea: Multi-disciplinary team of researchers identify mechanism of protection conferred by probiotic supplement
Probiotic-containing yogurt protects against microbiome changes that lead to antibiotic-induced diarrhea: Multi-disciplinary team of researchers identify mechanism of protection conferred by probiotic supplement
Eating yogurt containing a particular strain of a well-studied probiotic appears to protect against harmful changes in the gut microbiome that are associated with antibiotic administration.
·sciencedaily.com·
Probiotic-containing yogurt protects against microbiome changes that lead to antibiotic-induced diarrhea: Multi-disciplinary team of researchers identify mechanism of protection conferred by probiotic supplement
Probiotics in Pediatrics. A Review and Practical Guide
Probiotics in Pediatrics. A Review and Practical Guide
The potential benefit of the administration of probiotics in children has been studied in many settings globally. Probiotics products contain viable micro-organisms that confer a health benefit on the host. Beneficial effects of selected probiotic strains for the management or prevention of selected …
·pubmed.ncbi.nlm.nih.gov·
Probiotics in Pediatrics. A Review and Practical Guide
Application of Microbiome Management in Therapy for Clostridioides difficile Infections: From Fecal Microbiota Transplantation to Probiotics to Microbiota-Preserving Antimicrobial Agents
Application of Microbiome Management in Therapy for Clostridioides difficile Infections: From Fecal Microbiota Transplantation to Probiotics to Microbiota-Preserving Antimicrobial Agents
Oral vancomycin and metronidazole, though they are the therapeutic choice for Clostridioides difficile infections (CDIs), also markedly disturb microbiota, leading to a prolonged loss of colonization resistance to C. difficile after therapy; as a result, their use is associated with a …
·pubmed.ncbi.nlm.nih.gov·
Application of Microbiome Management in Therapy for Clostridioides difficile Infections: From Fecal Microbiota Transplantation to Probiotics to Microbiota-Preserving Antimicrobial Agents