FMT

FMT

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Integrated bioinformatics and multiomics reveal Liupao tea extract alleviating NAFLD via regulating hepatic lipid metabolism and gut microbiota - PubMed
Integrated bioinformatics and multiomics reveal Liupao tea extract alleviating NAFLD via regulating hepatic lipid metabolism and gut microbiota - PubMed
LPTE could be effective in preventing high-fat diet (HFD)-induced NAFLD by modulating hepatic lipid metabolism and gut microbiota. This study firstly integrated bioinformatics and multi-omics technologies to identify the potential active components and key microbiota associated with LPTE's effects, …
·pubmed.ncbi.nlm.nih.gov·
Integrated bioinformatics and multiomics reveal Liupao tea extract alleviating NAFLD via regulating hepatic lipid metabolism and gut microbiota - PubMed
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease - PubMed
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease - PubMed
Despite the observed decrease in liver fat associated with metabolic-associated fatty liver disease (MAFLD) in mice following fecal microbiota transplantation, the clinical effects and underlying mechanisms of washed microbiota transplantation (WMT), a refined method of fecal microbiota transplantat …
·pubmed.ncbi.nlm.nih.gov·
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease - PubMed
Fecal microbiota transplantation of patients with anorexia nervosa did not alter flexible behavior in rats - PubMed
Fecal microbiota transplantation of patients with anorexia nervosa did not alter flexible behavior in rats - PubMed
While our study did not reveal direct impacts of AN-associated gut microbiota on cognitive flexibility or anxiety behaviors in our preclinical model, we observed a decrease in task engagement after antibiotic-induced dysbiosis, underscoring that the presence of a gut microbiome matters. Our findings …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation of patients with anorexia nervosa did not alter flexible behavior in rats - PubMed
MicroRNA and Gut Microbiota Alter Intergenerational Effects of Paternal Exposure to Polyethylene Nanoplastics - PubMed
MicroRNA and Gut Microbiota Alter Intergenerational Effects of Paternal Exposure to Polyethylene Nanoplastics - PubMed
Nanoplastics (NPs), as emerging contaminants, have been shown to cause testicular disorders in mammals. However, whether paternal inheritance effects on offspring health are involved in NP-induced reproductive toxicity remains unclear. In this study, we developed a mouse model where male mice were a …
·pubmed.ncbi.nlm.nih.gov·
MicroRNA and Gut Microbiota Alter Intergenerational Effects of Paternal Exposure to Polyethylene Nanoplastics - PubMed
Balancing Act: Exploring the Gut Microbiota-Brown Adipose Tissue Axis in PCOS Pathogenesis and Therapeutic Frontiers - PubMed
Balancing Act: Exploring the Gut Microbiota-Brown Adipose Tissue Axis in PCOS Pathogenesis and Therapeutic Frontiers - PubMed
Polycystic ovary syndrome (PCOS) is a prevalent reproductive, endocrine, and metabolic disease that affects 5-18% of women worldwide, with a rising incidence. Hyperandrogenemia and insulin resistance are two key pathophysiological factors that contribute to PCOS, both of which contribute to a variet …
·pubmed.ncbi.nlm.nih.gov·
Balancing Act: Exploring the Gut Microbiota-Brown Adipose Tissue Axis in PCOS Pathogenesis and Therapeutic Frontiers - PubMed
Exploring the Significance of Gut Microbiota in Diabetes Pathogenesis and Management-A Narrative Review - PubMed
Exploring the Significance of Gut Microbiota in Diabetes Pathogenesis and Management-A Narrative Review - PubMed
Type 2 diabetes is a disease with significant health consequences for the individual. Currently, new mechanisms and therapeutic approaches that may affect this disease are being sought. One of them is the association of type 2 diabetes with microbiota. Through the enteric nervous system and the gut- …
·pubmed.ncbi.nlm.nih.gov·
Exploring the Significance of Gut Microbiota in Diabetes Pathogenesis and Management-A Narrative Review - PubMed
Fecal microbiota transplantation ameliorates high-fat diet-induced memory impairment in mice - PubMed
Fecal microbiota transplantation ameliorates high-fat diet-induced memory impairment in mice - PubMed
Gut dysbiosis is linked to metabolic and neurodegenerative diseases and comprises a plausible link between high-fat diet (HFD) and brain dysfunction. Here we show that gut microbiota modulation by either antibiotic treatment for 5 weeks or a brief 3-day fecal microbiota transplantation (FMT) regimen …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation ameliorates high-fat diet-induced memory impairment in mice - PubMed
Siderophore-harboring gut bacteria and fecal siderophore genes for predicting the responsiveness of fecal microbiota transplantation for active ulcerative colitis - PubMed
Siderophore-harboring gut bacteria and fecal siderophore genes for predicting the responsiveness of fecal microbiota transplantation for active ulcerative colitis - PubMed
A significant increase in Faecalibacterium, and decrease in Enterobacteriaceae and the total fecal siderophore genes copy number were observed in responders after FMT. The siderophore genes and its encoding bacteria may be of predictive value for the clinical responsiveness of FMT to active ulcerati …
·pubmed.ncbi.nlm.nih.gov·
Siderophore-harboring gut bacteria and fecal siderophore genes for predicting the responsiveness of fecal microbiota transplantation for active ulcerative colitis - PubMed
Role of the Microbiome and the Gut-Brain Axis in Alcohol Use Disorder: Potential Implication for Treatment Development - PubMed
Role of the Microbiome and the Gut-Brain Axis in Alcohol Use Disorder: Potential Implication for Treatment Development - PubMed
The gut microbiota is constituted by trillions of microorganisms colonizing the human intestine. Studies conducted in patients with alcohol use disorder (AUD) have shown altered microbial composition related to bacteria, viruses, and fungi.This review describes the communication pathways between the …
·pubmed.ncbi.nlm.nih.gov·
Role of the Microbiome and the Gut-Brain Axis in Alcohol Use Disorder: Potential Implication for Treatment Development - PubMed
Role of gut microbiota in regulating immune checkpoint inhibitor therapy for glioblastoma - PubMed
Role of gut microbiota in regulating immune checkpoint inhibitor therapy for glioblastoma - PubMed
Glioblastoma (GBM) is a highly malignant, invasive, and poorly prognosed brain tumor. Unfortunately, active comprehensive treatment does not significantly prolong patient survival. With the deepening of research, it has been found that gut microbiota plays a certain role in GBM, and can directly or …
·pubmed.ncbi.nlm.nih.gov·
Role of gut microbiota in regulating immune checkpoint inhibitor therapy for glioblastoma - PubMed
Osteopontin Depletion in Non-haematopoietic Cells Improves Outcomes in Septic Mice by Enhancing Antimicrobial Peptide Production - PubMed
Osteopontin Depletion in Non-haematopoietic Cells Improves Outcomes in Septic Mice by Enhancing Antimicrobial Peptide Production - PubMed
Osteopontin (Opn) depletion can improve septic outcomes, but the underlying mechanism remains unknown. In this study, we demonstrated that non-haematopoietic but not haematopoietic Opn depletion improved septic outcomes. Compared to wild-type (WT) mice, co-housed Opn-/- mice displayed enhanced produ …
·pubmed.ncbi.nlm.nih.gov·
Osteopontin Depletion in Non-haematopoietic Cells Improves Outcomes in Septic Mice by Enhancing Antimicrobial Peptide Production - PubMed
Targeting gut and intratumoral microbiota: a novel strategy to improve therapy resistance in cancer with a focus on urologic tumors - PubMed
Targeting gut and intratumoral microbiota: a novel strategy to improve therapy resistance in cancer with a focus on urologic tumors - PubMed
We explore how the composition and function of the gut microbiota influence the tumor microenvironment and immune response, ultimately impacting treatment outcomes. Additionally, we discuss emerging strategies targeting the microbiota to enhance therapeutic efficacy and overcome resistance. The appl …
·pubmed.ncbi.nlm.nih.gov·
Targeting gut and intratumoral microbiota: a novel strategy to improve therapy resistance in cancer with a focus on urologic tumors - PubMed
Modulation of gut microbiome in the treatment of neurodegenerative diseases: A systematic review - PubMed
Modulation of gut microbiome in the treatment of neurodegenerative diseases: A systematic review - PubMed
The effects of probiotic-related interventions depend on the patients' ND stage and pre-existing allopathic medication. Further studies on larger cohorts and long term comprehensive neuropsychiatric, metabolic, biochemical testing, and neuroimaging monitoring are necessary to optimize therapeutic pr …
·pubmed.ncbi.nlm.nih.gov·
Modulation of gut microbiome in the treatment of neurodegenerative diseases: A systematic review - PubMed
Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome - PubMed
Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome - PubMed
Our results demonstrate that HUA-induced gut dysbiosis contributes to the development of renal injury, possibly by promoting the production of gut-derived uremic toxins and subsequently activating the NLRP3 inflammasome. Our data suggest a potential therapeutic strategy for the treatment of renal di …
·pubmed.ncbi.nlm.nih.gov·
Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome - PubMed
Alleviation of fluoride-induced colitis by tea polysaccharides: Insights into the role of Limosilactobacillus vaginalis and butyric acid - PubMed
Alleviation of fluoride-induced colitis by tea polysaccharides: Insights into the role of Limosilactobacillus vaginalis and butyric acid - PubMed
Endemic fluorosis has gained increasing attention as a public health concern, and the escalating risk of colitis resulting from excessive fluoride intake calls for effective mitigation strategies. This study aimed to investigate the potential mechanisms underlying the alleviation of fluoride-induced …
·pubmed.ncbi.nlm.nih.gov·
Alleviation of fluoride-induced colitis by tea polysaccharides: Insights into the role of Limosilactobacillus vaginalis and butyric acid - PubMed
Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes - PubMed
Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes - PubMed
Compared to MHO, MUO subset symptom picture is featured by specific differences in gut pro-inflammatory taxa and metabolites that could have a role in the progression to metabolically unhealthy status and developing of obesity-related cardiometabolic diseases. The approach is suitable to better expl …
·pubmed.ncbi.nlm.nih.gov·
Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes - PubMed
The role of the gut microbiota in tumor, immunity, and immunotherapy - PubMed
The role of the gut microbiota in tumor, immunity, and immunotherapy - PubMed
In recent years, with the deepening understanding of the gut microbiota, it has been recognized to play a significant role in the development and progression of diseases. Particularly in gastrointestinal tumors, the gut microbiota influences tumor growth by dysbiosis, release of bacterial toxins, an …
·pubmed.ncbi.nlm.nih.gov·
The role of the gut microbiota in tumor, immunity, and immunotherapy - PubMed
Zn(II)-curcumin prevents cadmium-aggravated diabetic nephropathy by regulating gut microbiota and zinc homeostasis - PubMed
Zn(II)-curcumin prevents cadmium-aggravated diabetic nephropathy by regulating gut microbiota and zinc homeostasis - PubMed
Background: Diabetic nephropathy (DN) is known as the most common complication of diabetes, resulting from a complex inheritance-environment interaction without effective clinical treatments. Herein, we revealed the protective effects and mechanisms of Zn(II)-curcumin, a curcumin derivative, …
·pubmed.ncbi.nlm.nih.gov·
Zn(II)-curcumin prevents cadmium-aggravated diabetic nephropathy by regulating gut microbiota and zinc homeostasis - PubMed
Gut microbes improve prognosis of Klebsiella pneumoniae pulmonary infection through the lung-gut axis - PubMed
Gut microbes improve prognosis of Klebsiella pneumoniae pulmonary infection through the lung-gut axis - PubMed
In contrast to direct antibiotic treatment, faecal microbiota transplantation improves the prognosis of mice with pneumonia-derived sepsis caused by Klebsiella pneumoniae by improving the structure of the intestinal flora and increasing the level of beneficial metabolites, fatty acids and sec …
·pubmed.ncbi.nlm.nih.gov·
Gut microbes improve prognosis of Klebsiella pneumoniae pulmonary infection through the lung-gut axis - PubMed
Gut mycobiome alterations in obesity in geographically different regions - PubMed
Gut mycobiome alterations in obesity in geographically different regions - PubMed
The gut fungi play important roles in human health and are involved in energy metabolism. This study aimed to examine gut mycobiome composition in obese subjects in two geographically different regions in China and to identify specific gut fungi associated with obesity. A total of 217 subjects from …
·pubmed.ncbi.nlm.nih.gov·
Gut mycobiome alterations in obesity in geographically different regions - PubMed
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice - PubMed
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice - PubMed
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized inflammatory imbalance, intestinal epithelial mucosal damage, and dysbiosis of the gut microbiota. Polygonatum cyrtonema polysaccharides (PCPs) can regulate gut microbiota and inflammation. Here, the different doses …
·pubmed.ncbi.nlm.nih.gov·
Polygonatum cyrtonema polysaccharides reshape the gut microbiota to ameliorate dextran sodium sulfate-induced ulcerative colitis in mice - PubMed
What is the impact of microbiota on dry eye: a literature review of the gut-eye axis - PubMed
What is the impact of microbiota on dry eye: a literature review of the gut-eye axis - PubMed
By summarizing the changes in the ocular surface and intestinal microbiota when dry eye occurs, it is speculated and concluded that the intestine may affect the occurrence of eye diseases such as dry eye through several pathways and mechanisms, such as the occurrence of abnormal immune responses, mi …
·pubmed.ncbi.nlm.nih.gov·
What is the impact of microbiota on dry eye: a literature review of the gut-eye axis - PubMed