FMT

FMT

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Fecal microbiota transplantation in the treatment of hepatic encephalopathy: A perspective - PubMed
Fecal microbiota transplantation in the treatment of hepatic encephalopathy: A perspective - PubMed
Due to its complex pathogenesis, treatment of hepatic encephalopathy (HE) continues to be a therapeutic challenge. Of late, gut microbiome has garnered much attention for its role in the pathogenesis of various gastrointestinal and liver diseases and its potential therapeutic use. New evidence sugge …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation in the treatment of hepatic encephalopathy: A perspective - PubMed
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus - PubMed
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus - PubMed
Our study fills this knowledge gap by finding that alterations in gut microbiota have an independent impact on hyperglycemia and insulin resistance in the GDM state. In vivo and in vitro, gut dysbiosis is linked to adipose tissue inflammation and insulin resistance via the bacterial product SCFAs in …
·pubmed.ncbi.nlm.nih.gov·
Gut dysbiosis contributes to SCFAs reduction-associated adipose tissue macrophage polarization in gestational diabetes mellitus - PubMed
Alginate oligosaccharide-mediated butyrate-HIF-1α axis improves skin aging in mice - PubMed
Alginate oligosaccharide-mediated butyrate-HIF-1α axis improves skin aging in mice - PubMed
The "gut-skin" axis has been proved and is considered as a novel therapy for the prevention of skin aging. The antioxidant efficacy of oligomannonic acid (MAOS) make it an intriguing target for use to improve skin aging. The present study further explored whereby MAOS-mediated gut-skin axis balance …
·pubmed.ncbi.nlm.nih.gov·
Alginate oligosaccharide-mediated butyrate-HIF-1α axis improves skin aging in mice - PubMed
Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article - PubMed
Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article - PubMed
Background: The interaction between commensal bacteria and the host is essential for health and the gut microbiota-brain axis plays a vital role in this regard. Obesity as a medical problem not only affect the health of the individuals, but also the economic and social aspects of communities. …
·pubmed.ncbi.nlm.nih.gov·
Novel therapeutic strategy for obesity through the gut microbiota-brain axis: A review article - PubMed
NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis - PubMed
NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis - PubMed
Sepsis-associated encephalopathy (SAE) is a significant cause of mortality in patients with sepsis. Despite extensive research, its exact cause remains unclear. Our previous research indicated a relationship between non-hepatic hyperammonemia (NHH) and SAE. This study aimed to investigate the relati …
·pubmed.ncbi.nlm.nih.gov·
NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis - PubMed
Microbiota restoration therapies for recurrent Clostridioides difficile infection reach an important new milestone - PubMed
Microbiota restoration therapies for recurrent Clostridioides difficile infection reach an important new milestone - PubMed
Microbiota restoration therapy has become a standard treatment for recurrent Clostridioides difficile infection (rCDI). In this article, we review the studies supporting the licensure of two live biotherapeutic products (LBPs) designed to prevent rCDI and to provide clinicians with a perspect …
·pubmed.ncbi.nlm.nih.gov·
Microbiota restoration therapies for recurrent Clostridioides difficile infection reach an important new milestone - PubMed
Microbes in the tumor microenvironment: New additions to break the tumor immunotherapy dilemma - PubMed
Microbes in the tumor microenvironment: New additions to break the tumor immunotherapy dilemma - PubMed
Immunotherapies currently used in clinical practice are unsatisfactory in terms of therapeutic response and toxic side effects, and therefore new immunotherapies need to be explored. Intratumoral microbiota (ITM) exists in the tumor environment (TME) and reacts with its components. On the one hand, …
·pubmed.ncbi.nlm.nih.gov·
Microbes in the tumor microenvironment: New additions to break the tumor immunotherapy dilemma - PubMed
Exploring the Gut Microbiome's Role in Inflammatory Bowel Disease: Insights and Interventions - PubMed
Exploring the Gut Microbiome's Role in Inflammatory Bowel Disease: Insights and Interventions - PubMed
Inflammatory Bowel Disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is a chronic and relapsing inflammatory condition of the intestine that significantly impairs quality of life and imposes a heavy burden on healthcare systems globally. While the exact etiology of IBD is …
·pubmed.ncbi.nlm.nih.gov·
Exploring the Gut Microbiome's Role in Inflammatory Bowel Disease: Insights and Interventions - PubMed
RIGOROUS DONOR SELECTION FOR FMT IN ACTIVE ULCERATIVE COLITIS: KEY LESSONS FROM A RANDOMIZED CONTROLLED TRIAL HALTED FOR FUTILITY - PubMed
RIGOROUS DONOR SELECTION FOR FMT IN ACTIVE ULCERATIVE COLITIS: KEY LESSONS FROM A RANDOMIZED CONTROLLED TRIAL HALTED FOR FUTILITY - PubMed
The RESTORE-UC trial did not meet its primary endpoint of increased steroid-free clinical remission at week 8. Further research should additionally consider patient-selection, sterilized sham-control, increased frequency, density, and viability of FMT prior to administration.
·pubmed.ncbi.nlm.nih.gov·
RIGOROUS DONOR SELECTION FOR FMT IN ACTIVE ULCERATIVE COLITIS: KEY LESSONS FROM A RANDOMIZED CONTROLLED TRIAL HALTED FOR FUTILITY - PubMed
Development of an in vitro biofilm model of the human supra-gingival microbiome for Oral microbiome transplantation - PubMed
Development of an in vitro biofilm model of the human supra-gingival microbiome for Oral microbiome transplantation - PubMed
The high prevalence of dental caries and periodontal disease place a significant burden on society, both socially and economically. Recent advances in genomic technologies have linked both diseases to shifts in the oral microbiota - a community of 700 bacterial species that live within the mouth …
·pubmed.ncbi.nlm.nih.gov·
Development of an in vitro biofilm model of the human supra-gingival microbiome for Oral microbiome transplantation - PubMed
Relative dispersion ratios following fecal microbiota transplant elucidate principles governing microbial migration dynamics - PubMed
Relative dispersion ratios following fecal microbiota transplant elucidate principles governing microbial migration dynamics - PubMed
Microorganisms frequently migrate from one ecosystem to another. Yet, despite the potential importance of this process in modulating the environment and the microbial ecosystem, our understanding of the fundamental forces that govern microbial dispersion is still lacking. Moreover, while theoretical …
·pubmed.ncbi.nlm.nih.gov·
Relative dispersion ratios following fecal microbiota transplant elucidate principles governing microbial migration dynamics - PubMed
Unraveling the Microbiome-Human Body Axis: A Comprehensive Examination of Therapeutic Strategies, Interactions and Implications - PubMed
Unraveling the Microbiome-Human Body Axis: A Comprehensive Examination of Therapeutic Strategies, Interactions and Implications - PubMed
This review scrutinizes the intricate interplay between the microbiome and the human body, exploring its multifaceted dimensions and far-reaching implications. The human microbiome, comprising diverse microbial communities inhabiting various anatomical niches, is increasingly recognized as a critica …
·pubmed.ncbi.nlm.nih.gov·
Unraveling the Microbiome-Human Body Axis: A Comprehensive Examination of Therapeutic Strategies, Interactions and Implications - PubMed
Developing the Common Marmoset as a Translational Geroscience Model to Study the Microbiome and Healthy Aging - PubMed
Developing the Common Marmoset as a Translational Geroscience Model to Study the Microbiome and Healthy Aging - PubMed
Emerging data support associations between the depletion of the healthy gut microbiome and aging-related physiological decline and disease. In humans, fecal microbiota transplantation (FMT) has been used successfully to restore gut microbiome structure and function and to treat C. difficile i …
·pubmed.ncbi.nlm.nih.gov·
Developing the Common Marmoset as a Translational Geroscience Model to Study the Microbiome and Healthy Aging - PubMed
[Advances in the application of fecal microbiota transplantation for the treatment of nervous system diseases] - PubMed
[Advances in the application of fecal microbiota transplantation for the treatment of nervous system diseases] - PubMed
The intestinal microbiota exhibits a strong correlation with the function of the central nervous system, exerting influence on the host brain through neural pathways, immune pathways, and microbial metabolites along the gut-brain axis. Disorders in the composition of the intestinal microbial are clo …
·pubmed.ncbi.nlm.nih.gov·
[Advances in the application of fecal microbiota transplantation for the treatment of nervous system diseases] - PubMed
Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I-IV studies from Clinicaltrials.gov - PubMed
Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I-IV studies from Clinicaltrials.gov - PubMed
Some studies were terminated during phase II, and FMT was less effective than antibiotics such as vancomycin and fidaxomicin. However, colonoscopy and oral FMT were explored in several completed studies with promising results, but the evidence remains limited and inconclusive.
·pubmed.ncbi.nlm.nih.gov·
Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I-IV studies from Clinicaltrials.gov - PubMed
A Comparison of Currently Available and Investigational Fecal Microbiota Transplant Products for Recurrent Clostridioides difficile Infection - PubMed
A Comparison of Currently Available and Investigational Fecal Microbiota Transplant Products for Recurrent Clostridioides difficile Infection - PubMed
Clostridioides difficile infection (CDI) is an intestinal infection that causes morbidity and mortality and places significant burden and cost on the healthcare system, especially in recurrent cases. Antibiotic overuse is well recognized as the leading cause of CDI in high-risk patients, and …
·pubmed.ncbi.nlm.nih.gov·
A Comparison of Currently Available and Investigational Fecal Microbiota Transplant Products for Recurrent Clostridioides difficile Infection - PubMed
Clinical Applications of the Gut Microbiome in Genitourinary Cancers - PubMed
Clinical Applications of the Gut Microbiome in Genitourinary Cancers - PubMed
Recently recognized as one of the hallmarks of cancer, the microbiome consists of symbiotic microorganisms that play pivotal roles in carcinogenesis, the tumor microenvironment, and responses to therapy. With recent advances in microbiome metagenomic sequencing, a growing body of work has demonstrat …
·pubmed.ncbi.nlm.nih.gov·
Clinical Applications of the Gut Microbiome in Genitourinary Cancers - PubMed
Heat stress-induced dysbiosis of the gut microbiota impairs spermatogenesis by regulating secondary bile acid metabolism in the gut - PubMed
Heat stress-induced dysbiosis of the gut microbiota impairs spermatogenesis by regulating secondary bile acid metabolism in the gut - PubMed
Heat stress (HS) poses a substantial challenge to livestock. Studies have demonstrated that HS reduces fertility and leads to gut microbiota dysbiosis in bulls. However, the impact of the gut microbiota on fertility in bulls during HS is still unclear. Our research revealed that HS exposure decrease …
·pubmed.ncbi.nlm.nih.gov·
Heat stress-induced dysbiosis of the gut microbiota impairs spermatogenesis by regulating secondary bile acid metabolism in the gut - PubMed
Icaritin-curcumol activates CD8+ T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer - PubMed
Icaritin-curcumol activates CD8+ T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer - PubMed
ICA-CUR mediates the interaction between gut microbiota and the DNMT1/IGFBP2 axis to inhibit the progression of PCa by regulating immune response and metabolism, suggesting a potential therapeutic strategy for PCa.
·pubmed.ncbi.nlm.nih.gov·
Icaritin-curcumol activates CD8+ T cells through regulation of gut microbiota and the DNMT1/IGFBP2 axis to suppress the development of prostate cancer - PubMed
Fecal microbiota transplantation significantly improved respiratory failure of amyotrophic lateral sclerosis - PubMed
Fecal microbiota transplantation significantly improved respiratory failure of amyotrophic lateral sclerosis - PubMed
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that leads to respiratory failure, and eventually death. However, there is a lack of effective treatments for ALS. Here we report the results of fecal microbiota transplantation (FMT) in two patients with late-onset class …
·pubmed.ncbi.nlm.nih.gov·
Fecal microbiota transplantation significantly improved respiratory failure of amyotrophic lateral sclerosis - PubMed
The Impact of Microbiome Interventions on the Progression and Severity of Inflammatory Bowel Disease: A Systematic Review - PubMed
The Impact of Microbiome Interventions on the Progression and Severity of Inflammatory Bowel Disease: A Systematic Review - PubMed
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation. The dysbiotic gut microbiome likely contributes to IBD pathogenesis. Microbiome-directed therapies such as fecal microbiota transplantation (FMT), probi …
·pubmed.ncbi.nlm.nih.gov·
The Impact of Microbiome Interventions on the Progression and Severity of Inflammatory Bowel Disease: A Systematic Review - PubMed
Human-derived fecal microbiota transplantation alleviates social deficits of the BTBR mouse model of autism through a potential mechanism involving vitamin B6 metabolism - PubMed
Human-derived fecal microbiota transplantation alleviates social deficits of the BTBR mouse model of autism through a potential mechanism involving vitamin B6 metabolism - PubMed
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by social communication deficiencies and stereotypic behaviors influenced by hereditary and/or environmental risk factors. There are currently no approved medications for treating the core symptoms of ASD. H …
·pubmed.ncbi.nlm.nih.gov·
Human-derived fecal microbiota transplantation alleviates social deficits of the BTBR mouse model of autism through a potential mechanism involving vitamin B6 metabolism - PubMed
Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis - PubMed
Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis - PubMed
Rheumatoid arthritis (RA) is an autoimmune disease. Early studies hold an opinion that gut microbiota is environmentally acquired and associated with RA susceptibility. However, accumulating evidence demonstrates that genetics also shape the gut microbiota. It is known that some strains of inbred la …
·pubmed.ncbi.nlm.nih.gov·
Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis - PubMed