FMT

Researchers provide an overview of fecal microbiota transplantation in treating recurrent Clostridioides difficile infection.

Immune checkpoint inhibitors (ICIs) target advanced malignancies with high efficacy but also predispose patients to immune-related adverse events like immune-mediated colitis (IMC). Given the association between gut bacteria with response to ICI therapy and subsequent IMC, fecal microbiota transplan …

A microbial network involving Muribaculaceae and other oxalate-degrading bacteria achieved by FMT was capable of reducing urinary oxalate excretion and CaOx crystal deposition in the kidney through increasing intestinal oxalate degradation. FMT may exert a renoprotective function in oxalate-related …

Mounting evidence points to causative or correlative roles of gut microbiome in the development of a myriad of diseases ranging from gastrointestinal diseases, metabolic diseases to neurological di...

Candace Cotto, RN, reviews the process of incorporating fecal microbiota, live-jslm treatment into clinical practice, what patients can expect, and the room sanitation process after the procedure.

Continuing the development of #FMT capsules to improve gut microbiome in patients with life-threatening diseases. Thanks @HepGas @AarhusUni_int @Innofond @novonordiskfond pic.twitter.com/Wm1MrSl8un— Christian Hvas (@ChristianHvas) June 11, 2023

We are beyond associations. An active role of the altered gut #microbiota is demonstrated in #IBD (see #FMT studies notably). #Circular_Causality https://t.co/HZdX2JaKji— Harry Sokol (@h_sokol) June 7, 2023

This report illustrated why donor screening for #FMT should be evidence-based and we should keep asking questions. Indeed, we found no transmission of H. pylori or other risks following FMT regardless of donor H. pylori carrier status— Christian Hvas (@ChristianHvas) June 11, 2023

Recent scientific research has indicated that the gut microbiota constitutes a nuanced, diverse ecosystem of microorganisms that have gained significant attention due to its crucial involvement in shaping human health and diseases. In particular, the gut microbiota plays a pivotal role in cancer pre …

Gut microbiota dysbiosis plays a role in the pathophysiology of cardiovascular and metabolic disorders, but the mechanisms are not well understood. Fecal microbiota transplantation (FMT) is a valuable approach to delineating a direct role of the total microbiota or isolated species in disease pathop …

It is established that gut microbiota dysbiosis is implicated in arsenic (As)-induced neurotoxic process, however, the underlying mode of action remains largely unclear. Here, through remodeling gut microbiota on As-intoxicated pregnancy rats using fecal microbiota transplantation (FMT) from Control …

FMT can reduce TG level, reconstruct intestinal microecological structure, change body metabolism and function, and alleviate inflammatory response by reducing the relative abundance of harmful bacteria in patients with severe pneumonia during the convalescence period.

Ever heard of #fical #transplant? Why is it done? Dr. Prof Narasimhaiah Srinivasaiah, Colorectal Surgeon, Apollo Hospital Bannerghatta Road, explains about fiscal transplant, which is the infusion of bacteria or to be more specific the bacteria in stool from a normal healthy person to a person with health complications. He tells us this could be a treatment for #IBS(Irritable Bowel Syndrome), #collitis, #mental disorders #autism etc. To book an appointment: https://www.askapollo.com/doctors/colorectal-surgery/bangalore/dr-prof-narasimhaiah-srinivasaiah #ficaltransplant #ficaltransplanttratment #ApolloHospital #ApolloHospitalsBangalore #ApolloCancerCentres #ApolloHospitalBannrghattaRoad

The gut microbiota is an emerging target for improving brain health during ageing - Volume 4

An effective treatment for a whole raft of diseases, from irritable bowel syndrome to arthritis and even Alzheimer’s, comes from the most unlikely of sources – human poo. James Kinross explains the role gut biomes play in our health

Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1) blockade in cancer patients, but the mechanisms underlying their immunosuppressive effects remain unknown. By inducing the down-regulation of mucosal addressin cell adhesion molecule 1 (MAdCAM-1) in the ileum, post-A …

In brief, 919 Syrup may downregulate the ratio of hippocampal metabolites erucamide to 5-AVAB by regulating intestinal flora to alleviate postpartum depression, laying a scientific foundation for future pathological research and development of therapeutic drugs for postpartum depression.

Diabetic retinopathy (DR) is the most common and detrimental microvascular complication of diabetes mellitus. It has become one of the top causes of blindness and visual impairment in the working-age population. However, prevention and treatment options for DR are limited, invasive, and expensive, a …

Engineering the Microbiome: How Synthetic Biology is Shaping the Future of Human Health - CityLife

Already successful in treating C difficile, fecal microbiota transplant could be applied to noncommunicable diseases, but better understanding of donor-recipient pairing is critical.

The human gut microbiome contains the largest number of bacteria in the body and has the potential to greatly influence metabolism, not only locally but also systemically. There is an established link between a healthy, balanced, and diverse microbiome and overall health. When the gut microbiome becomes unbalanced (dysbiosis) through dietary changes, medication use, lifestyle choices, environmental factors, and ageing, this has a profound effect on our health and is linked to many diseases, including lifestyle diseases, metabolic diseases, inflammatory diseases, and neurological diseases. While this link in humans is largely an association of dysbiosis with disease, in animal models, a causative link can be demonstrated. The link between the gut and the brain is particularly important in maintaining brain health, with a strong association between dysbiosis in the gut and neurodegenerative and neurodevelopmental diseases. This link suggests not only that the gut microbiota composition can be used to make an early diagnosis of neurodegenerative and neurodevelopmental diseases but also that modifying the gut microbiome to influence the microbiome–gut–brain axis might present a therapeutic target for diseases that have proved intractable, with the aim of altering the trajectory of neurodegenerative and neurodevelopmental diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, autism spectrum disorder, and attention-deficit hyperactivity disorder, among others. There is also a microbiome–gut–brain link to other potentially reversible neurological diseases, such as migraine, post-operative cognitive dysfunction, and long COVID, which might be considered models of therapy for neurodegenerative disease. The role of traditional methods in altering the microbiome, as well as newer, more novel treatments such as faecal microbiome transplants and photobiomodulation, are discussed.

Vowst is supplied in a bottle containing 12 capsules.

The FDA granted a pharma company a literal monopoly on shit.

Fecal transplants are the most effective treatment for C. diff infections.

Anaerobic stool collection device that ensures the microbiota viability and original composition by creating an anaerobic atmosphere.

👏Phenomenal work by @ArielleElkrief et al #ASCO23 @ASCOFecal #Microbiota transplant in immune-related #colitis🔸Proteobacteria-predominated dysbiosis is characteristics in IR-colitis 🔸Healthy donor #FMT➡️clinical improvement in IR-colitis (80%)👏@motzermd @vandenBrinkLab… pic.twitter.com/z9FWcwn1op— Nazli Dizman (@NazliDizman) June 4, 2023

Humans harbour large quantities of microbes, including bacteria, fungi, viruses and archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota and gut barrier dysfunction. Preclinical models demonstrate the importance of the gut microbiota in the pathogenesis of various liver diseases. In this review, we discuss how manipulation of the gut microbiota can be used as a novel treatment approach for liver disease. We summarise current data on untargeted approaches, including probiotics and faecal microbiota transplantation, and precision microbiome-centered therapies, including engineered bacteria, postbiotics and phages, for the treatment of liver diseases.

Great intro to the conversation we all need to be having about the #microbiome & its role in #autoimmunity & chronic disease. However think #FMT will prove to be a red herring... Focus shd be on role of #bile acids in shaping microbial diversity. That's where the magic happens. https://t.co/DXz777e9RZ— Elizabeth Wells (@NaturallyWells) June 5, 2023