Modulating gut microbiota to treat cancer
FMT
The interplay of gut microbiota between donors and recipients determines the efficacy of fecal microbiota transplantation
Fecal microbiota transplantation (FMT) is a promising treatment for microbiota dysbiosis associated diseases, such as Clostridioides difficile infection (CDI) and inflammatory bowel disease (IBD). The engraftment of donor bacteria is essential for the effectiveness of FMT, which to some exten …
Frozen Stool Preparations: What About Stability and the Preservation of the Microbiome?
Fecal microbiota transplantation is the infusion of specially prepared stool from a healthy donor into the gut of a recipient to restore a healthy microbial community
A study casts doubt on the contribution of altered gut microbiota in autism spectrum disorder-related behaviors
Joyce Mak on Twitter
Latest #FMT for IBS study from 🇯🇵https://t.co/qruLFifeVw17 refractory #IBS😷FMT (4 donors), colonoscopyResults58.8% Responders (IBS-SI🔼50 #12 weeks)Responders tend to have 🔼a-diversity increased and similarity to donor microbiome. No severe SE.#GITwitter #MedTwitter pic.twitter.com/TLmIau5p1U— Kewin Siah (@KewinSiah) July 16, 2022
Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan
People bank blood. Why not faeces? - The Economist
Storing your stools when you are young may help you later in life
Fecal Microbiota Transplantation and Health Outcomes: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials - PubMed
Although we found that FMT was positively associated with several outcomes, caution should be exercised in choosing this approach, given the insufficient number of primary studies, low methodological quality, and low quality of evidence. Further high-quality randomized controlled trials with long-te …
The potential benefits of fecal microbiota transplantation in obesity could rely on supplementation of low-fermentable fiber
A new proof-of-principle study reveals that supplementing low-fermentable fiber following fecal microbiota transplantation may improve insulin sensitivity in individuals with severe obesity.
Exploring the connection between Parkinson's disease and gut microbiota to uncover potential therapeutic targets
Scientists have published a new review focusing on the relationship between PD and gut microbiota.
Frontiers | Fecal Microbiota Transplantation Treatment of Autoimmune-mediated Type 1 Diabetes Mellitus.
Type 1 Diabetes Mellitus (T1DM) is an autoimmune-mediated disease characterized by reduced or absolute lack of insulin secretion and often associated with a range of vascular and neurological complications, for which there is a lack of effective treatment other than lifestyle interventions and pharmacological treatments such as insulin injections. Studies have shown that the gut microbiota is involved in mediating the onset and development of many fecal and extrafecal diseases, including autoimmune type 1 diabetes. In recent years, many cases of gut microbiota transplantation for intra- and extra-fecal diseases have been reported worldwide, and this approach has been shown safe and effective. Here, we conducted an experimental treatment study in two adolescent patients diagnosed with autoimmune type 1 diabetes for one year. Patients received two to three normal fecal microbiota transplants (FMT) and were followed for 30 weeks. Clinical outcomes were measured, including biochemical indices, medication regimen, and dosage adjustment. Fecal microbiota macrogenomic sequencing after transplantation provides a reference for more reasonable and effective microbiota transplantation protocols to treat autoimmune type 1 diabetes. Our results suggest that FMT is an effective treatment for autoimmune type 1 diabetes.
Treatment of IBS Using FMT: A Step Forward? - Gastroenterology
FMT Is Cost Effective for Any Recurrent Clostridioides Difficile Infection, Study Says - AJMC.com Managed Markets Network
Research found fecal microbiota transplantation (FMT) to be an optimal cost-effective treatment strategy for first and subsequent recurrent Clostridioides difficile infection (CDI), challenging current guidelines.
Fecal microbiota transplantation for irritable bowel syndrome: An intervention for the 21 st century - PubMed
Irritable bowel syndrome (IBS) affects about 12% of the global population. Although IBS does not develop into a serious disease or increase mortality, it results in a considerable reduction in the quality of life. The etiology of IBS is not known, but the intestinal microbiota appears to play a pivo …
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation - PubMed
This study shows that colonic enteroendocrine cells densities significantly change in responders group that received donor-FMT. The mechanisms for the cross talks between gut microbiota and colonic enteroendocrine cells remain to be investigated.
Fecal transplantation for the treatment of Clostridioides difficile recurrent infection
[Fecal transplantation for the treatment of Clostridioides difficile recurrent infection]
A Systematic Review of the Efficacy and Safety of Fecal Microbiota Transplantation in the Treatment of Hepatic Encephalopathy and Clostridioides difficile Infection in Patients With Cirrhosis
The microbiome of the human gut and liver coexists by influencing the health and disease state of each system. Fecal microbiota transplantation (FMT) has recently emerged as a potential treatment for conditions associated with cirrhosis, such as hepatic encephalopathy and recurrent/refractory Clo …
Excessive Antibiotic Use Can Also Cause Diarrhoea: Did You Know This? | TheHealthSite.com - TheHealthSite
Could Your Old Poop Cure You of Future Diseases? | WIRED
Fecal transplants can fix gut diseases, but finding the right donor stool is tricky. The solution, some scientists believe, is to keep a store of your own.
Crazie Daizee on Twitter
Fascinating concept to seriously consider (tho vague doping risk) Elites could store their own sample at peak fitness to someday recover from chronic illness/fatigue (or donate to others who are ill as the science improves for filtering/pair-matching) #FMT https://t.co/VrA4A0YVAu— Crazie Daizee (@Crazie_Daizee) July 9, 2022
Efficacy of fecal microbiota transplantation for patients with irritable bowel syndrome at three years after transplantation - Gastroenterology
Cambridge microbiome company looks beyond fecal transplants - The Boston Globe
Vedanta Biosciences will use its new manufacturing facility to make bacteria-filled pills that heal the gut microbiome without the need for stool donors
Aileen Bui on Twitter
“We have limited antibiotic choices for recurrent #Cdiff. While #FMT (fecal microbiota transplantation) is an effective option, access is limited.
Will oral microbiome therapies, like SER-109, be the next breakthrough?
@SeresTX
@AmCollegeGastro
#GITwitter #IDtwitter”
Cutting Edge: Poop therapy can save your gut, and your life - The Indian Express
Stool or faecal microbial transplant (FMT) has helped contain infections in bone marrow transplant patients and even restore good gut bacteria, says Dr Parikshit Prayag, infectious disease consultant and in-charge of the Centre of Excellence in Infectious Diseases at Deenanath Mangeshkar Hospital, Pune.
‘Dark matter’ beyond the bacteria in faecal microbiota transplantation | Nature Reviews Gastroenterology & Hepatology
Nature Reviews Gastroenterology & Hepatology - ‘Dark matter’ beyond the bacteria in faecal microbiota transplantation
Mapping the Neighborhoods of the Gut Microbiome - The Scientist
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
Will You Be Depositing at the 'Stool Bank' Someday? - HealthDay News
THURSDAY, June 30, 2022 (HealthDay News) -- Banking samples of your own poop in your youth and then transplanting them back when you're old might be a key to healthy aging, scientists suggest.Stool samples frozen and stored when a person is vital and healthy could potentially rejuvenate bacteria in ...
Banking stool samples may improve healthy aging - UPI News
Banking samples of your own poop in your youth and then transplanting them back when you're old might be a key to healthy aging, scientists suggest.
Novel Biome on Twitter
We recognize the importance of providing accessible treatment for families worldwide. We have 4 treatment locations in Mexico, Hungary, Australia, and Panamá. Our treatment location in Mexico is located in Rosarito, 1 hour from the San Diego International Airport.#autism #fmt pic.twitter.com/nnuCeDtDaI— Novel Biome (@NovelBiome) July 1, 2022
You Need to Make a Personal Poop Bank, Scientists Say - The Daily Beast
Don’t flush that toilet. Your gut health might thank you one day.