H5N1 Flu

The duck CD8+ T-cell response effectively defends against H5N1 highly pathogenic avian influenza virus (HPAIV) infection, but the recognized peptide is rarely identified. Here, we found that the ratio of CD8+ T cells and the expression of IFN-γ and cytotoxicity-associated genes …

From December 2023 to March 2024, a surveillance program aiming to detect Highly Pathogenic Avian Influenza (HPAI) H5N1 was conducted on Antarctica territories, specifically at Fildes Peninsula (King George Island, Maritime Antarctic), and James Ross Island. At Fildes Peninsula, samples from marine …

Avian influenza is not a new disease, but the emergence of high pathogenicity avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 lineage (Gs/GD) has necessitated fundamental changes to prevention and control strategies for this disease. No longer just an avian disease, avian influenza is c …

H5Nx A/Goose/Guangdong/1/96 Eurasian lineage high pathogenicity avian influenza (HPAI) viruses have been the main HPAI strains detected globally since 2005. These have spread around the world, causing a panzootic that has spanned six continents, with continual threat to not only wild and captive bir …

Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns over a possible future pandemic. Here, we performed an analysis of epitope data curated in the …

Our findings showed that common cranes are highly susceptible to natural infection with the HPAI H5N1 virus of clade 2.3.4.4b and may serve as bio-sentinels for the presence of the HPAI virus in wildlife.

A $1.26 million grant, awaiting final approval from Gov. Tim Walz, was awarded to University of Minnesota researchers intent on collecting 9,000 swabs from wild birds and mammals found sick or dead.

Experts warn the virus' spread to apex predators signals broader ecological risks and highlights the challenges of managing wildlife diseases.

As bird flu rips through poultry and dairy farms, it’s not just the rare human cases that are alarming experts. There are now reports across the U.S. of bird flu threatening, and in some cases, killing endangered animals at zoos. NBC News' David Noriega has the details.

Twenty big cats, including a Bengal tiger, several cougars, and a lynx, died after contracting bird flu at an animal sanctuary in Shelton, Washington earlier this month.

Another bird flu outbreak reported at a Norfolk poultry farm, raising concerns over the spread of the disease in commercial farming

LONDON: Bird farms across England's eastern coast had to enforce preventative bird flu measures starting Monday after a spate of cases were detected in the latest outbreak of the virus.

The state issued an alert Christmas Eve about Morasch Meats of Portland’s voluntary recall of Northwest Naturals’ two-pound feline turkey recipe.

Scientists are frustrated that the USDA again failed to include basic information about H5N1 genetic sequences from cows when the data were released this week.

Due to length constraints on virological.org posts, we are splitting this report into two parts that should be read as a single report. This is Part 1, containing Background, Data, Methods, and Findings sections 1 through 5. See Part 2 for Findings sections 6 through 9, Concluding remarks, Acknowledgements, and References. Michael Worobey, University of Arizona, Tucson, AZ 85705, USA Karthik Gangavarapu, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, ...

Since late 2021, a panzootic of highly pathogenic H5N1 avian influenza virus has driven significant morbidity and mortality in wild birds, domestic poultry, and mammals. In North America, infections in novel avian and mammalian species suggest the potential for changing ecology and establishment of new animal reservoirs. Outbreaks among domestic birds have persisted despite aggressive culling, necessitating a re-examination of how these outbreaks were sparked and maintained. To recover how these viruses were introduced and disseminated in North America, we analyzed 1,818 Hemagglutinin (HA) gene sequences sampled from North American wild birds, domestic birds and mammals from November 2021-September 2023 using Bayesian phylodynamic approaches. Using HA, we infer that the North American panzootic was driven by ∼8 independent introductions into North America via the Atlantic and Pacific Flyways, followed by rapid dissemination westward via wild, migratory birds. Transmission was primarily driven by Anseriformes, shorebirds, and Galliformes, while species such as songbirds, raptors, and owls mostly acted as dead-end hosts. Unlike the epizootic of 2015, outbreaks in domestic birds were driven by ∼46-113 independent introductions from wild birds, with some onward transmission. Backyard birds were infected ∼10 days earlier on average than birds in commercial poultry production settings, suggesting that they could act as “early warning signals” for transmission upticks in a given area. Our findings support wild birds as an emerging reservoir for HPAI transmission in North America and suggest continuous surveillance of wild Anseriformes and shorebirds as crucial for outbreak inference. Future prevention of agricultural outbreaks may require investment in strategies that reduce transmission at the wild bird/agriculture interface, and investigation of backyard birds as putative early warning signs. ### Competing Interest Statement The authors have declared no competing interest.

New research is the latest to show that raw milk can be a viable transmission route for bird flu.

A 2.5-year-old returning to Australia from India was infected with a reassortant H5N1 virus, revealing genetic mixing between avian influenza clades and gaps in South Asian surveillance.

Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined our previously established model of lethal ...

Since early 2022 highly pathogenic avian influenza (HPAI) H5N1 virus infections have been reported in wild aquatic birds and poultry throughout the United States (US) with spillover into several mammalian species1-6. In March 2024, HPAIV H5N1 clade 2.3.4.4b was first detected in dairy cows in Tex...

H5 bird flu is causing outbreaks in wild birds and poultry, other animals and sporadic human cases.

A Washington County cat has died from Bird Flu after eating raw cat food made by Morasch Meats.

In a significant development, the United States has reported its first severe case of H5N1 bird flu infection in a human.

MANHATTAN (KSNT) – The Kansas State University (K-State) Veterinary Health Center reported Tuesday it is not taking any more poultry or wild birds due to a rise in bird flu cases. K-State iss…

The rising incidence of bird flu in the Central Valley is raising serious concerns for public health and food safety. The detection of the virus in dairy cattle has sparked alarm, as it increases the risk of transmission to other animals and potentially to humans. In response, biosecurity measures have been strengthened to protect the population and ensure food quality.

Just when we thought we'd gotten back to some version of "normal" after the terrible years of the COVID-19 pandemic, now there are growing cases of bird

Bird flu infections among dairy cows and the humans exposed to them are rising. This is what scientists are watching for