H5N1 Vaccine

Paul Klotman and Anthony Maresso, both of Baylor College of Medicine, say the U.S. needs to act now to prevent an H5N1 pandemic.

Novel galectin antagonist blocks H5N1 virus entry, potentially eliminating need for mass culling. Bioxytran's breakthrough could revolutionize poultry disease management.

Life science companies developing bird flu vaccines are gaining attention as the avian influenza subtype H5N1 becomes an increasing concern. The United States is in the midst of an H5N1 bird flu outbreak that began in February 2024 and is now threatening the nation’s poultry and cattle industries. W...

Pandemic influenza remains a significant global health threat, as signalled by the circulation and cross-species transmission of avian influenza A(H5N1) viruses from the clade 2.3.4.4b, including among dairy cattle in the USA since 2024. Although most of the reported human infections from the USA so far1,2 have been mild, the virus can change its profile rapidly. To reduce mortality and morbidity from influenza in humans, vaccines remain the most important intervention.

By Gary Ford, policy advisor, BFREPA February has been a challenging month for the poultry sector with the ongoing threat and indeed cases of Avian flu in [...]

Researchers from Diosynvax Ltd. presented data from a study that aimed to evaluate the efficacy of a pan-H5 vaccine designed using computational biology and being developed for protection against avian influenza.

(Reuters) -The Netherlands, one of the world's largest egg exporters, has launched a pilot program on a laying-hen farm to vaccinate poultry against bird flu with the aim of achieving large-scale

In an interview with Fox News host Sean Hannity, Kennedy explained that his main concern with inoculating chickens is that if the vaccine does not completely prevent infection it could help spawn n…

Therapeutic drugs should be “intensively” tested on US poultry flocks infected with bird flu, Health and Human Services Secretary Robert F. Kennedy Jr. said, arguing that the medications could help identify treatments for human cases.

bulldozer belches a black cloud of exhaust as the engine revs. A mound of dead chickens flops into a hole in the earth. Highly Pathogenic Avian Influenza

Vaccinated eggs to be sold only within Netherlands

Belgium is also struggling with the virus, with multiple infections detected across the country in recent weeks.

Manx Care says it wants to lower the risk of handlers getting human and avian flu at the same time.

No current vaccine meets the full criteria for deployment to tackle the UK's ongoing bird flu outbreak, the avian influenza vaccination task force says.

Plans to use vaccination to prevent avian influenza in poultry flocks have been turned down, the UK avian influenza vaccination task force has confirmed.

Arcturus Therapeutics believes it’s “highly unlikely” it will lose the promised government funding for its bird flu mRNA vaccine trial, despite reports swirling that Moderna’s own financial support | Arcturus believes it’s “highly unlikely” it will lose the government funding for its mRNA bird flu vaccine trial, despite rumors swirling that Moderna’s funding will be revoked.

Health and Human Services Secretary Robert F. Kennedy Jr. warned vaccines could turn "birds into mutant factories."

The US Department of Agriculture announced it will allocate $100 million to develop vaccines and other therapies to help contain the spread of bird flu on poultry and dairy farms

Elanco shares next steps for its avian flu vaccine partnership with Medgene targeted at dairy cattle.

But it’s still unclear when USDA will approve deployment.

The race is underway.

As H5N1 influenza A (bird flu) spreads, the need for a vaccine grows. Do seasonal flu vaccines protect against H5N1? What current H5N1 vaccines exist—and what developments are underway?

MicroRNAs (miRNAs) are key regulators of gene expression, exerting post-translational control through mRNA silencing or degradation. These molecules play pivotal roles in host–pathogen interactions, particularly in modulating antiviral immune responses. The global public health threat posed by the H5N1 Highly Pathogenic Avian Influenza (HPAI) virus necessitates urgent exploration of novel therapeutic strategies. Our investigation revealed significant dysregulation of miR-18a-5p following influenza virus infection, observed consistently across both in vitro and in vivo models. Experimental evidence demonstrated that miR-18a-5p overexpression effectively inhibits H5N1 virus propagation through multiple mechanisms: (1) in vitro studies using A549 cells transfected with miR-18a-5p mimics showed a substantial reduction in viral replication; (2) animal models (mice and chickens) with elevated miR-18a-5p expression exhibited markedly suppressed AIV replication, reduced pathogenicity, and improved survival rates. The therapeutic potential of miR-18a-5p was particularly evident in its ability to significantly decrease mortality rates in H5N1-infected animals. Furthermore, this miRNA demonstrated robust protective effects against virus-induced lung damage, suggesting its dual role in both preventing and treating H5N1 infections. These findings position miR-18a-5p as a promising candidate for the development of broad-spectrum antiviral interventions, offering a novel strategic approach to combat this serious public health challenge.

It’s been a month now since a Rose Acre Farms egg production facility in Jackson County was hit with Bird Flu—leading to the depopulation of more than 2.6 million birds at their Cort Acre Egg Farm near

The latest actions by federal health authorities overseen by Robert F. Kennedy Jr. on vaccine development and evaluation are raising alarms among public health experts about the nation’s ability to handle a major health crisis like bird flu.

Poll: New strains of Highly Pathogenic Avian Influenza are prey to conspiracy theories just like with COVIDRead more →

Medgene's 'protein-based prescription-platform vaccine' nears USDA approval for cattle vaccination, with meat and dairy from field-tested vaccinated cattle likely already in the food supply.

With the COVID-19 pandemic still fresh in the minds of many U.S. citizens, concerns over the government’s ability to contain emerging health threats persist. The ongoing struggle to control the H5N1 bird flu outbreak has raised alarms, particularly as the virus has begun spreading beyond poultry to cows and even humans. While the likelihood of a pandemic remains low, if one does occur, it could be as disruptive as 2020, if not worse.