Long Covid Symptoms

As the nation searches for ways to reduce the number of young people diagnosed with type 2 diabetes, a new prevention pathway is emerging: avoiding COVID-19.

Early research that suggested children face little risk from the coronavirus has been retracted. Studies say long-term risk is real.

As part of a nationwide study, VCU School of Nursing researchers make a significant advancement in understanding the long-term effects of COVID-19 in pediatric patients.

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine. ...

A 12-year-old girl from Yeovil has shared her experience with Long Covid to...

Pediatric long COVID is more common than many thought, and we keep letting kids be reinfected with new variants

Scientists investigating long COVID in youth found similar but distinguishable patterns between school-age children (ages 6-11 years) and adolescents (ages 12-17 years) and identified their most common symptoms.

Watch Long COVID patients suffer high rate of autonomic disorders, researchers say Video Online, on GlobalNews.ca

Pediatric patients aged 10 to 19 years old diagnosed with COVID-19 have a higher risk of new-onset type 2 diabetes within six months compared to those diagnosed with other respiratory infections, according ...

The following is a summary of “Temporal trajectories of long-COVID symptoms in adults with 22 months follow-up in a prospective cohort study in Norway,” published in the October 2024 issue of Infectious Disease by Ellingjord-Dale et al. Researchers conducted a retrospective study to address the lack of large studies on long-COVID symptoms with pre-COVID-19 symptom

By Caitlin Hanbury Despite extensive research, there is still a significant lack of understanding on the impact long COVID has on children and adolescents. But a nationwide study with contributions made by nurse scientists at the Virginia Commonwealth University School of Nursing is helping to set new standards in diagnosing and treating this condition. Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by symptoms that continue six weeks beyond initial COVID-19 infection. An estimated 65 million people are affected worldwide. Published in the Journal of the American Medical Association (JAMA), the research provides crucial insights into the prolonged effects of COVID-19 infections, marking a significant advancement in understanding pediatric long COVID. “This publication highlights the tremendous value of collaboration among experts from various fields, who have come together to better understand the complex nature of this condition,” said Patricia Kinser, Ph.D., interim dean of the School of Nursing and one of the study’s lead researchers. “This study is just one step in a broader effort to drive future research and implement care strategies that will make a tangible difference in the lives of those affected.” With a clearer understanding of pediatric long COVID symptoms, researchers and clinicians can now refine diagnostic tools and treatments. (VCU School of Nursing) Kinser and Amy Salisbury, Ph.D., associate dean of Research, Scholarship, and Innovation at the School of Nursing, are leading a multi-institutional research consortium focused on long COVID pediatric patients as part of the Researching COVID to Enhance Recovery (RECOVER) initiative, a nationwide study funded by the National Institutes of Health. The RECOVER-Pediatrics study involved over 5,000 participants between the ages of 6 to 17, recruited from more than 60 health care and community care settings across the United States between March 2022 and December 2023. The study will continue following these participants while also actively recruiting new ones to expand its findings and further the research. Key findings in long COVID and pediatrics study The study had several key goals such as identifying common long-term symptoms, how distinct patterns of symptoms – known as phenotypes – overlap across age groups and creating new guidelines to help health care providers more accurately diagnose and treat long COVID in pediatric and adolescent patients. The published study reveals a significant prevalence of prolonged symptoms among participants with a history of COVID-19 infection. Among the 898 school-age children and 4,469 adolescents surveyed, 14 symptoms were found to be more prevalent in those who had a COVID-19 infection compared to those who had not been infected. This research represents a significant leap forward in our understanding of what long COVID looks like across age groups... Amy Salisbury, Ph.D., associate dean of Research, Scholarship, and Innovation at the School of Nursing Distinct symptom patterns were also identified between age groups as well. For school-age children, neurocognitive problems, pain, and gastrointestinal symptoms were particularly prominent. In contrast, adolescents experienced more frequent changes in smell or taste, pain, and fatigue or malaise. The researchers used these findings to develop targeted guidelines for diagnosing and managing pediatric long COVID. These guidelines assist in identifying children and adolescents who are at high risk for long COVID and help address the associated decline in overall health and quality of life. “This research represents a significant leap forward in our understanding of what long COVID looks like across age groups, laying the groundwork for improved diagnosis, treatment, and quality of life for affected children and adolescents,” Salisbury said. Future research and promise for enhanced treatments The impact of this research extends beyond the study’s immediate findings, paving the way for future work in several key areas. With a clearer understanding of distinct symptom patterns associated with pediatric long COVID, researchers and clinicians can now refine diagnostic tools and treatment protocols tailored specifically for children and adolescents. In turn, this will drive the development of more effective, age-appropriate interventions and support systems to address their unique needs. As the RECOVER initiative continues into the next phase, future research will explore the long-term trajectories of pediatric long COVID, investigate how symptoms evolve over time and their impact on quality of life. Additionally, researchers will seek to identify potential genetic factors that may predispose individuals to more severe or persistent symptoms, creating avenues for personalized treatment approaches. Learn more about the RECOVER pediatrics study and its participants, visit https://bit.ly/RECOVERkids or contact the study team at recoverkidsva@vcu.edu. Having a hand in science: Hear from the families who joined the VCU project to study long COVID in children

The extent of long COVID worldwide is an economic tragedy. If a cure were found, many labour shortages might end. But at the moment, all doctors have is anecdotal evidence

Background Previous studies have suggested that zinc deficiency (ZD) may increase the risk of short-term mortality in patients with coronavirus disease 2019 (COVID-19). However, the relations...

A JAMA study finds COVID-19 caused a 127,931 deficit in cancer diagnoses in 2020, with recovery in 2021 influenced by demographic and community characteristics.

Background Patients with long COVID may experience various concomitant symptoms caused by inflammation, which affect their lives and well-being. In this study, we aimed to (1) investigate the prevalence of long COVID; (2) explore the levels of symptom severity and functional disability owing to long COVID, overall health, and their relationship; and (3) conduct exploratory factor analysis of long COVID-19 symptoms among experienced infected population in the capital of Thailand. Methods A cross-sectional research design was used and a sample of 337 community members with previously COVID-19 infection in Bangkok, Thailand was recruited for this study. Purposive sampling was used. Data collection was performed using an online and a paper-based questionnaire. Descriptive statistics (number, percentage), odds ratio, exploratory factor analysis, and Spearman’s rank correlation coefficient were used for the data analysis. Results The prevalence of long COVID was 32.9%. The main reported symptoms included anxiety (28.5%), fatigue (26.1%), and dyspnea (13.4%). There was a significant relationship between symptom severity and functional disability (rs=0.385, p value

Scientific Reports - Impact of post-COVID symptoms on activity and participation of women and men

Sacral neuromodulation (SNM) is an effective third-line therapy for overactive bladder (OAB). COVID-19 may have a temporary negative effect on SNM function. We describe two cases of increased se...

Two posters presented at the CHEST 2024 annual meeting highlighted the importance of addressing socioeconomic disparities and identifying clinical predictors to improve outcomes and survival rates among patients with idiopathic pulmonary fibrosis (IPF).

It has been more than four years since the COVID-19 pandemic began, yet millions of people continue to suffer long-term effects from the virus. Despite thousands of studies, many clinicians remain unsure of how to evaluate and manage people with long COVID.

New research using three decades of data uncovers the key risk factors for long COVID in postmenopausal women.

The objective of the AHA scientific statement is to review the available evidence on for better management of cardiac arrhythmias from COVID causes that are still encountered on a regular basis.

Background The post COVID-19 health condition of Chinese residents infected with Omicron is not clear after the change of epidemic prevention policies. This study aimed to clarify the epidemiology and associated factors about health status of rehabilitation patients. Methods A quick questionnaire study based on C19-YRSm was conducted in mainland China through internet from May 1, 2023, to May 7, 2023. Chinese native speakers infected with Omicron variant agreed to participate were included. Persisting symptom and living habits were simultaneously inquired. Logistic regression analysis was used to identify the associated factors. Results In this study 753 individuals were included. Of whom 57.90% were males, 89.38% did not seek medical service, 99.47% recovered within less than 120 days. Breathlessness (47.68%), cognitive impairment (44.89%), Anxiety/mood changes (33.20%), pain/discomfort (32.94%), fatigue or tiredness not improved by rest (32.27%) and post-exertional malaise (30.01%) were the top reported key symptoms. Less than 10% respondents reported functional limitations. The prevalence of fever was reported greater than that of other symptoms, with dry eyes at 14.87%, appetite change at 14.34%, and hair loss at 12.22%. Middle age (OR: 2.353, 95%CI: 1.171 ~ 4.729), underlying diseases (OR: 2.293, 95%CI: 1.216 ~ 4.324), severe key symptom (OR: 6.168, 95%CI: 1.376 ~ 27.642) and at least one other symptom (OR: 1.847, 95%CI: 1.225 ~ 2.718)during the recovery were the risk factors of poor overall health after infection (current overall health score

Introduction: This study aimed to assess and compare the long-term non-cardiac complications of the multisystem inflammatory syndrome in children (MIS-C) triggered by consecutive variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Material and methods: Multisystem...

This research identifies a potential link between COVID-19 vaccines and facial palsy, calling for enhanced surveillance and understanding of vaccine safety.

Background The COVID-19 pandemic negatively impacted tuberculosis (TB) treatment services, including directly observed therapy (DOT) programs used to promote medication adherence. We compared DOT adherence embedded in a research study before and after COVID-19 lockdowns in South Africa. Methods We analyzed data from 263 observational study participants undergoing drug susceptible (DS)-TB DOT between May 2017 to March 2022. Participants enrolled before October 2019 were considered ‘pre-COVID-19’ and those enrolled after September 2020 were considered ‘post-COVID-19 lockdown groups. Negative binomial regression models were used to compare DOT non-adherence rates between the two lockdown groups. We then conducted a sensitivity analysis which only included participants enrolled in the immediate period following the first COVID-19 lockdown. Results DOT non-adherence rate was higher in the post-COVID-19 lockdown group (aIRR = 1.42, 95% CI = 1.04–1.96; p = 0.028) compared to pre-COVID-19 lockdown period, adjusting for age, sex, employment status, household hunger, depression risk, and smoked substance use. DOT non-adherence was highest immediately following the initial lockdown (aIRR = 1.74, 95% CI = 1.17–2.67; p = 0.006). Conclusion The COVID-19 lockdowns adversely effected adherence to TB DOT in the period after lockdowns were lifted. The change in DOT adherence persisted even after adjusting for socioeconomic and behavioral variables. We need a better understanding of what treatment adherence barriers were exacerbated by COVID-19 lockdowns to improve outcomes in post-pandemic times. Trial registration ClinicalTrials.gov Registration Number: NCT02840877. Registered on 19 July 2016.

Trigeminal neuralgia has been described as one of the worst types of pain known to humanity.

This cohort study assesses the risk of development of type 2 diabetes in pediatric patients aged 10 to 19 years after receiving a COVID-19 diagnosis compared with the risk after other non–COVID-19 respiratory infections during the first 2 years of the pandemic.