Something I've never really paid attention to, and it's actually quite a powerful feature: when doing search/repalce in Emacs you can replace with Elisp code (as in, Elisp code can provide the replacement).
wyuenho/emacs-pet: Tracks down the correct Python tooling executables from your virtualenvs so you can glue the binaries to Emacs and delete code in init.el
What looks to be a module for Emacs that helps find the right venv for a project; I think. Saving this to look at at some point in the future.