Covid19-Sources

Emergence of novel variants of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable immunity. Here we report the evaluation of a ferritin nanoparticle vaccine displaying the receptor-binding domain of the SARS-CoV-2 spike protein (RFN) adjuvanted with Army Liposomal Formulation QS-21 (ALFQ). RFN vaccination of macaques using a two-dose regimen resulted in robust, predominantly Th1 CD4+ T cell responses and reciprocal peak mean neutralizing antibody titers of 14,000-21,000. Rapid control of viral r...

Wer als Kind verwaist, hat noch Jahrzehnte später ein erhöhtes Suizid-Risiko. Besonders groß ist die Gefahr, wenn die Kinder jünger als sechs Jahre sind. Dabei reagieren Jungen anders als Mädchen auf den Verlust eines Elternteils.

Vorschlag für ein effektiveres (reaktiveres) Steuerinstrument im #Corona Management.(Request for Comments)🔵 Maßnahmen sollten kombiniert an die Inzidenz und die Veränderung der Inzidenz gebunden werden.1/16— Christian Fries (@f2135) March 21, 2021

Dirk Westhölter, Christian Taube; SARS-CoV-2 outbreak in a long-term care facility after vaccination with BNT162b2, Clinical Infectious Diseases, , ciab299, htt

Background While the leading symptoms during coronavirus disease 2019 (COVID-19) are acute and the majority of patients fully recover, a significant fraction of patients now increasingly experience long-term health consequences. However, most data available focus on health-related events after severe infection and hospitalization. We present a longitudinal, prospective analysis of health consequences in patients who initially presented with no or minor symptoms of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection. Hence we focus on mild COVID-19 in non-hospitalized...

Berlin – Das Robert-Koch-Institut (RKI) schätzt das Übertragungsrisiko von SARS-CoV-2 durch vollständig geimpfte Personen als geringer ein als durch symptomlose... #RKI #Coronaimpfung #Virusuebertragung #Studie

There clearly is no PCR crisis or false positive plague or casedemic. The false-positive PCR problem is not a problem.

#COVID19Sehr gute Nachrichten! Studie zu inhalativem Budesonid ist jetzt im @TheLancet veröffentlicht (bisher nur preprint). In der frühen Krankheitsphase verhindert Budesonid häufig schwere Verläufe, schnellere Genesung. Keine rel. Nebenwirkungen. https://t.co/DGB5NV3eRc— 🔴 Dominik Scharpf (@dscharpfMD) April 11, 2021

Auf Facebook werden Grippe-Todesfälle mit Corona-Todesfällen verglichen. Das ist irreführend, die Zahlen werden unterschiedlich erhoben.

The SARS-CoV-2 pandemic has been raging for over a year, creating global detrimental impact. The BNT162b2 mRNA vaccine has demonstrated high protection levels, yet apprehension exists that several variants of concerns (VOCs) can surmount the immune defenses generated by the vaccines. Neutralization assays have revealed some reduction in neutralization of VOCs B.1.1.7 and B.1.351, but the relevance of these assays in real life remains unclear. Here, we performed a case-control study that examined whether BNT162b2 vaccinees with documented SARS-CoV-2 infection were more likely to become infec...

Background. Seroprevalence studies have proven an important tool to monitor the progression of the coronavirus disease 2019 (COVID–19) epidemic. We present results of consecutive population-based seroprevalence surveys performed in Denmark in 2020. Methods. Invitation letters including a questionnaire covering symptoms were sent to representatively drawn samples of the population in spring, late summer and autumn/winter of 2020. Blood samples from participants taken at public test-centers were analyzed for total Ig and seroprevalence estimates per population segment calculated and compared ...

A calculator for building intuition about COVID risk. We used published research to estimate the risk level of various activities in microCOVIDs. 1 microCOVID is a one-in-a-million chance of getting COVID. We hope you'll use this tool to make safer choices.

Wie zuverlässig eigentlich ein Schnell- oder Selbst-Test auf Sars-CoV-2 ist, lässt sich unmöglich allgemein beantworten. Diese Seite möchte bei der Abschätzung helfen.

We frequently encounter Machine Learning algorithms, from Google Translator to Snapchat filters. In this article, we present to you the five branches of Machine Learning and their key concepts.

Stellungnahme des Arbeitsausschusses Feinstäube (AAF) von DECHEMA/ProcessNet, GDCh und KRdL

NEW: just updated our excess deaths figures, including data into AprilIt’s abundantly clear that Latin America is the hardest-hit region in the world, with the five highest excess death rates globally. The UK is 21st out of 48 countries, and the US 24thhttps://t.co/JxVd2cG7KI pic.twitter.com/DxNPGA2wNt— John Burn-Murdoch (@jburnmurdoch) April 6, 2021

Hautärzte wollen das Virus in alten Proben gefunden haben.

Im Kampf gegen die Corona-Pandemie könnte es in Hamburg ein neues Frühwarnsystem geben. Dazu soll das Abwasser genauer untersucht werden.

Ein Forschungsteam der TU Darmstadt kann Corona-Viren im Abwasser nachweisen. Die Methode wird bislang aber nur im Ausland angewendet. In Deutschland zögern die Behörden.

The FT analyses the scale of outbreaks and tracks the vaccine rollouts around the world

A minority of people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmit most infections. How does this happen? Sun et al. reconstructed transmission in Hunan, China, up to April 2020. Such detailed data can be used to separate out the relative contribution of transmission control measures aimed at isolating individuals relative to population-level distancing measures. The authors found that most of the secondary transmissions could be traced back to a minority of infected individuals, and well over half of transmission occurred in the presymptomatic phase. F...

In this Perspective, Cobey, Larremore, Grad and Lipsitch argue that dose-sparing regimens of COVID-19 vaccines can reduce disease incidence, prevalence and burden and explain why they think that such strategies would also slow the rate of viral escape from vaccine or naturally induced immunity.

Our study provides evidence for substantial neurological and psychiatric morbidity in the 6 months after COVID-19 infection. Risks were greatest in, but not limited to, patients who had severe COVID-19. This information could help in service planning and identification of research priorities. Complementary study designs, including prospective cohorts, are needed to corroborate and explain these findings.

Six of 12 men wintering at an isolated Antarctic base sequentially developed symptoms and signs of a common cold after 17 weeks of complete isolation. Examination of specimens taken from the men in relation to the outbreak has not revealed a causative ...

The new SARS-CoV-2 variant has evoked scenes reminiscent of the early days of covid-19 when much of the world banned travel to and from Wuhan, China. With large parts of south-east England locked down, Elisabeth Mahase looks at what we know so far Yes, according to a review of the current evidence by the UK’s New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG). Its 18 December report said that the rate of transmission of the variant, known as B.1.1.7 or VUI 202012/01 (variant under investigation, year 2020, month 12, variant 01), was 71% (95% confidence interval 67% to 75%),...

In the last few days, the question of why more drug companies haven't been enlisted for vaccine production has come up. It's mostly due to this tweet: The problem is, as far as I can see, this is simply wrong. There are not "dozens of other pharma companies" who "stand ready" to produce these

Abstract. Thrombocytopenia has been consistently reported following the administration of adenoviral gene transfer vectors. The mechanism underlying this phenom