Study shows endothelial cell targeting could help fight COVID-19 symptoms
For COVID-19 patients with serious lung disease, targeting endothelial cells—cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream—may be a novel ...
First 10 days after leaving hospital carry high risk for COVID-19 patients, study finds
In the first months after their COVID-19 hospital stay, patients face a high risk of ongoing health problems, trips back to the hospital, and death, a growing number of studies has shown.
Statistisches Bundesamt Deutschland - GENESIS-Online: Die Datenbankdes Statistischen Bundesamtes
GENESIS-Online ist eine Datenbank, die tief gegliederte Ergebnisse der amtlichen Statistik enthält. Sie wird kontinuierlich ausgebaut. Der Tabellenabruf erfolgt unentgeltlich und kann variabel auf den individuellen Bedarf angepasst werden. Die Abspeicherung der Ergebnisse ist in verschiedenen Formaten möglich.
Deaths registered weekly in England and Wales, provisional - Office for National Statistics
Provisional counts of the number of deaths registered in England and Wales, including deaths involving the coronavirus (COVID-19) pandemic, by age, sex and region.
Sonderauswertung zu Sterbefallzahlen des Jahres 2020 - Statistisches Bundesamt
22. Januar 2021 - Die Infektionen mit dem neuartigen Coronavirus stellen weltweit die Gesundheitssysteme vor große Herausforderungen. Die Zahl der Todesfälle in diesem Zusammenhang variiert von Land zu Land. Wie groß sind die direkten und indirekten Auswirkungen der Pandemie auf die Gesamtzahlen der Sterbefälle in Deutschland? Zur Beantwortung dieser Frage stellt das Statistische Bundesamt vorläufige Auszählungen von Sterbefallmeldungen der Standesämter tagesgenau als Sonderauswertung zur Verfügung, bevor die regulären Ergebnisse der amtlichen Sterbefallstatistik vorliegen. Aktuell ist e...
Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on all-cause mortality in 21 industrialized countries | Nature Medicine
Application of Bayesian models to vital statistics data from 21 industrialized countries shows that approximately 206,000 additional people died than if the COVID-19 pandemic had not occured. The heterogeneous distribution of excess deaths across the countries reflects differences in how the pandemic has been managed as well as the resilience of healthcare systems in these nations.
Sterbefallzahlen in der 47. Kalenderwoche 9 % über dem Durchschnitt der Vorjahre - Statistisches Bundesamt
Nach vorläufigen Ergebnissen sind in der 47. Kalenderwoche (16. bis 22. November 2020) in Deutschland mindestens 19 600 Menschen gestorben. Wie das Statistische Bundesamt (Destatis) weiter mitteilt, liegen die Sterbefallzahlen somit in diesem Zeitraum etwa 9 % über dem Durchschnitt der Jahre 2016 bis 2019. Dies geht aus einer Sonderauswertung der vorläufigen Sterbefallzahlen hervor, die aktuell bis zur 47. Kalenderwoche zur Verfügung steht.
Excess Deaths From COVID-19 and Other Causes, March-July 2020 | Cardiology | JAMA | JAMA Network
This study updates a previous report of the estimated number of excess deaths in the US during the coronavirus disease 2019 (COVID-19) pandemic through August 1, 2020, and describes causes of those deaths and temporal relationships with state lifting of coronavirus restrictions.
To Spread or Not to Spread SARS-CoV-2—Is That the Question? | Infectious Diseases | JAMA Pediatrics | JAMA Network
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has upended society in many ways. The tragic and rising number of deaths we continue to see throughout the world, the overloaded hospitals, the devastated economies1—all of these appropriately garner daily front-page...
Covid-19 outbreak in Manaus suggests herd immunity may not be possible | New Scientist
Though 76 per cent of people in Manaus, Brazil have covid-19 antibodies, the virus is spreading quickly – potentially fuelled by a new variant – which may mean herd immunity by infection is not possible
Covid-19 mit 20 Jahren: 104 Tage lang geht es Pascal "super" - dann ist er tot - FOCUS Online
Ein 20-jähriger Krankenpfleger steckt sich mit dem Coronavirus an. Milder Verlauf. Rasche Genesung, so scheint es. Doch vier Monate später stirbt er. Warum?
Interview with Virologist Christian Drosten:"I Am Quite Apprehensive about What Might Otherwise Happen in Spring and Summer" - DER SPIEGEL
In an interview with Christian Drosten, the German virologist looks back on the mistakes he has made in the coronavirus pandemic – and ahead to the dangers that the pandemic still has in store for us.
Data up to: Thursday, January 21 Notes: A figure showing federal states is now available below. Due to a technical malfunction, the data from 4-7.12.2020 are unfortunately not available. These graphics are updated regularly. They give a general picture of mobility reduction in Germany due to Covid-19 mobility restrictions. window.PlotlyConfig = {MathJaxConfig: 'local'}; window.PLOTLYENV=window.PLOTLYENV || {}; if (document.getElementById("a7693f6d-885d-479c-bf3e-1ab3a95a87dd")) { Plotly.newPlot( "a7693f6d-885d-479c-bf3e-1ab3a95a87dd", [{"fill": "toself", "fillcolor": "#EEE", "
1/ New #LongCovid prevalence figures by age and sex out by @ONS today. Prevalence of any symptom at 5 wks after positive test: 27% at age 35-4926% at age 50-6925% at age 25-3418% at >=7017% at age 17-2415% at age 12-1613% at age 2-1021% males24% females#CountLongCovid— Dr Nisreen Alwan 🌻 (@Dr2NisreenAlwan) January 21, 2021
Study Indicates Lockdowns Have Increased Deaths of Despair – AIER
"Regardless of whether they think lockdowns work, policymakers must be cognizant of the fact shutting down society also leads to excess deaths. Whether it’s from the government policies themselves...
Revisiting the UK’s strategy for delaying the second dose of the Pfizer covid-19 vaccine - The BMJ
Neutralising antibody immunity likely to fall with delayed dose, say these authors There is ongoing debate about the UK government’s decision to delay the second dose of the Pfizer/BioNTech vaccine [...]More...
Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine-elicited human sera | bioRxiv
Recently, a new SARS-CoV-2 lineage called B.1.1.7 has emerged in the United Kingdom that was reported to spread more efficiently than other strains. This variant has an unusually large number of mutations with 10 amino acid changes in the spike protein, raising concerns that its recognition by neutralizing antibodies may be affected. Here, we investigated SARS-CoV-2-S pseudoviruses bearing either the Wuhan reference strain or the B.1.1.7 lineage spike protein with sera of 16 participants in a previously reported trial with the mRNA-based COVID-19 vaccine BNT162b2. The immune sera had equiva...
SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma | bioRxiv
SARS-CoV-2 501Y.V2, a novel lineage of the coronavirus causing COVID-19, contains multiple mutations within two immunodominant domains of the spike protein. Here we show that this lineage exhibits complete escape from three classes of therapeutically relevant monoclonal antibodies. Furthermore 501Y.V2 shows substantial or complete escape from neutralizing antibodies in COVID-19 convalescent plasma. These data highlight the prospect of reinfection with antigenically distinct variants and may foreshadow reduced efficacy of current spike-based vaccines. ### Competing Interest Statement The aut...
