Health

A tree called Terminalia bellirica which falls in the Combretaceae family, is usually called Bahera or Beleric myrobalan. For a long time, people in ancient medicine, mainly Ayurveda, have used nushu to help with many kinds of illnesses. We have examined how T. bellerica protects against free radicals and helps control inflammatory problems related to chronic illnesses. Terminalia bellirica’s strong anti-inflammatory and antioxidant effects are due to its flavonoids, gallic acid, ellagic acid, tannins and other phenolic compounds. As such, it is believed to help treat diseases like diabetes, heart disease, various disorders of the nervous system and problems of the respiratory system that involve inflammation and stress from oxidative agents. It sums up recent findings on the medicinal plant and suggests research directions needed to better use its medicinal properties.

Terminalia bellirica, commonly referred to as Balela, is a plant belonging to the Combretaceae family, which has been extensively employed in both preventative and therapeutic medicine. In Unani medicine, it is a widely used herbal drug for the treatment of several ailments, including obesity, atherosclerosis, gastrointestinal disorders, memory loss, premature greying of hair, weakened immune system, loss of eyesight, general weakness, and ageing. The present review article aims to provide a comprehensive account of Terminalia bellirica, describing its medicinal uses, pharmacological actions, therapeutic properties, and chemical constituents. Furthermore, the article provides an overview of the plant's properties. The study highlights the potential of Terminalia bellirica as a valuable source of medicinal compounds, which can be harnessed for the development of novel therapeutic agents.

Terminalia bellerica (T. bellerica) is a tree belonging to the family Combretaceae. In Ayurvedic system of medicine, it is used as "health-harmonizer" in combination with Terminalia chebula and Emblica officnalis. It is a large deciduous tree found all over in Asia, mostly native to Sri Lanka. Traditionally, T. bellerica is used for treatment of various diseases such as conjunctivitis, asthma, migraine, baldness, constipation and weak eyesight. It contains various phytoconstituents such as glycosides, flavonoids, tannins, phenolic compound, amino acids and saponins which are responsible for various pharmacological activities like anti-diabetic, anti-microbial, anti-salmonella, anti-biofilm, anticancer, hepatoprotective, anti-pyretic and anti-diarrheal. This review article provides comprehensive information on pharmacognostic, phytochemical and pharmacological properties of T. bellerica, as a source for further research studies.

1. The pharmacokinetics of methylprednisolone (MP) were studied in five normal subjects following intravenous doses of 20, 40 and 80 mg methylprednisolone sodium succinate (MPSS) and an oral dose of 20 mg methylprednisolone as 4 x 5 mg tablets. ...

The temporal variations in the pharmacokinetics and pharmacodynamics of methylprednisolone at 8 am versus 4 pm were investigated in six healthy male volunteers. Subjects completed three phases: no drug administration, 20 mg intravenous ...

In this second installment about narcissism, we will explore the eight different types of narcissists. This is based on Dr. Ramani Durvasula’s work and book, titled “’Don’t You Know Who I Am?’ How to stay sane in an era of narcissism, entitlement, and incivility,” as well as Dr. Ramani’s videos on YouTube.

Are narcissists more prone to dementia? Unraveling the link between narcissism and heightened dementia risk, this article delves into the impact of self-centered traits on cognitive health. Discover how chronic stress and isolation exacerbate cognitive decline, and learn about brain-healthy practices to mitigate these risks. Explore practical steps and future research avenues to combat cognitive decline in narcissistic individuals.

Traits of narcissism may be adaptive or maladaptive. On a spectrum, narcissism can be overt, covert, antagonistic, communal, or malignant.

Enhanced bioavailability and pharmacokinetics of a novel hybrid-hydrogel formulation of fisetin orally administered in healthy individuals: a randomised double-blinded comparative crossover study - Volume 11

Kurkuma ist eine erstaunliche Pflanzenart mit einem weiten Spektrum für gesundheitliche Vorteile. Ein Beitrag von mir zählt das breit gefächerte Spektrum von Wirksamkeiten von Kurkuma auf:

Fatty liver supplements can be effective in helping you heal—but take these important lifestyle steps first.

Scientific Reports - A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles

These results provided the first evidence that nattokinase can be measured directly in the blood of humans. The results further suggest that a larger, more extensive, pharmacokinetic study of nattokinase is warranted. Additionally, looking for intact enzyme and bioactive nattokinase peptides should …

The effects of nattokinase on the in vitro platelet aggregation and in vivo thrombosis were investigated in comparison with aspirin. Rabbit platelet-rich plasma was incubated with nattokinase and aggregation inducers collagen and thrombin, and the ...

PDF | Nattokinase (NK) is a fibrinolytic enzyme produced by Bacillus subtilis. This enzyme comes from a traditional Japanese fermented food called... | Find, read and cite all the research you need on ResearchGate

Background: Healthy aging is defined as survival to advanced age while retaining autonomy in activities of daily living, high societal participation, and good quality of life. Sarcopenia, insomnia, cognitive impairment, and changes in sensation can ...

PDF | Background Taurine has become a popular supplement among athletes attempting to improve performance. While the effectiveness of taurine as an... | Find, read and cite all the research you need on ResearchGate

Low circulating taurine concentrations have been proposed as a driver of the aging process. We found that circulating taurine concentrations increased or remained unchanged with age in three geographically distinct human cohorts as well as in nonhuman ...

Scientific Reports - Evaluation of the neuroprotective effect of taurine in Alzheimer’s disease using functional molecular imaging

Alzheimer’s disease (AD) stands as one of the predominant neurodegenerative disorders, often culminating in dementia. Taurine, an endogenous amino acid, holds pivotal regulatory functions within the physiological milieu. Emerging evidence suggests ...

Glycine and cysteine are non-essential amino acids that are required to generate glutathione, an intracellular tripeptide that neutralizes reactive oxygen species and prevents tissue damage. During aging glutathione demand is thought to increase, ...

Oxidative stress (OxS) and mitochondrial dysfunction are implicated as causative factors for aging. Older adults (OAs) have an increased prevalence of elevated OxS, impaired mitochondrial fuel‐oxidation (MFO), elevated inflammation, endothelial ...

Elevated oxidative stress (OxS), mitochondrial dysfunction, and hallmarks of aging are identified as key contributors to aging, but improving/reversing these defects in older adults (OA) is challenging. In prior studies, we identified that ...

Background: Nutrition is increasingly becoming a greater part of medicine and in particular surgery. Pertinent nutritional clinical goals involve reducing recovery times by supplementing patients with additional nutrients and to prepare them for elective surgery so that recovery can be optimised. To assist in achieving the aforementioned outcomes within musculoskeletal surgery, supplementation with creatine and protein/Essential Amino Acids (EAA) can be a useful addition to patient care. Methods: A systematic review was performed using EMBASE, Scopus and Medline as search engines. This yielded 200 articles of which nine were included within the analysis. Findings: Two articles investigated creatine supplementation in orthopaedic knee surgery whilst seven focused on protein supplementation. Both creatine studies investigated pre and post-operative supplementation and found that creatine did not augment recovery of muscular strength. Whilst the six of the protein supplementation studies reported positive post-operative effects in respect to increases in strength and muscle mass. However no study matching the search criteria investigated the combination of both creatine and protein, likewise no study was found to report the speed of post-operative recovery with supplementation. Conclusion: Supplementation with protein/EAA’s is beneficial for those in the post-operative period in helping to reduce muscle atrophy and improve wound healing. There is limited evidence regarding the effects of creatine supplementation within such clinical populations, however there is a very good safety profile for both protein/EAA and creatine highlighting that supplementation is safe and can be experimented with. Keywords Protein • Creatine • Supplements • Knee • Hip • Elective musculoskeletal surgery • Enhanced recovery • Orthopaedic surgery • Recovery

Numerous health conditions affecting the musculoskeletal, cardiopulmonary, and nervous systems can result in physical dysfunction, impaired performance, muscle weakness, and disuse-induced atrophy. Due to its well-documented anabolic potential, ...

Numerous natural products found in our diet, such as polyphenols and flavonoids, can prevent the progression of cancer. Luteolin, a natural flavone, p…

Objectives To assess the role of ultrasensitive PSA values (usPSA) after radical prostatectomy in predicting the subsequent biochemical recurrence (BCR). Material and methods The study included 18...

AbstractThe diagnosis of appendicitis may be difficult to establish even for the experienced surgeon. Considerable variability in presenting symptoms and signs, resulting in part from the numerous locations in which the appendix may be found, contributes ...