A couple days ago, Ásgeir Thor Johnson convinced Claude to give up its system prompt. The prompt is a good reminder that chatbots are more than just their model. They’re tools and instructions that accrue and are honed, through user feedback and design.

Have a natural, spoken conversation with AI! Contribute to KoljaB/RealtimeVoiceChat development by creating an account on GitHub.

Minimal AI agent framework that just works with only seven tools. - aperoc/toolkami

Interesting release from Google, as a follow-up [to Gemma 3](https://simonwillison.net/2025/Mar/12/gemma-3/) from last month: To make Gemma 3 even more accessible, we are announcing new versions optimized with Quantization-Aware Training …

Therapeutics Commons (TDC): Multimodal Foundation for Therapeutic Science - mims-harvard/TDC

Give local LLMs superpowers with Open WebUI Tools. Use & build tools for function calling, API access (email/calendar) & real actions.

Contribute to asgeirtj/system_prompts_leaks development by creating an account on GitHub.

The simplest, fastest repository for training/finetuning small-sized VLMs. - huggingface/nanoVLM

Open AI Ollama Catalyst

Last week, I published some thoughts on Meta’s eventual repositioning as a kind of television channel stocked with generated material for any given user: Then TikTok came around and did away with two expectations: that you should have to work to figure out what you want to be entertained by, and that your best source […]

Artificial Neural Engine Machine Learning Library. Contribute to Anemll/Anemll development by creating an account on GitHub.

In this chapter we will explore models that can propose and rank catalysts for a given reaction transform. The methodology uses graph-based deep learning models trained on a moderate sized corpus o…

I have literally never seen LLM writing that actually improved my life.

Run GPT-4-level code edits locally. 100% offline. MIT licensed.

Learn how to run Qwen3 models locally on your Mac with MLX and create an autonomous coding agent using Localforge - completely free!

Create stunning original music in seconds using AI. Make your own masterpieces, share with friends, and discover music from artists worldwide.

Model Context Protocol -- Exploits, Risks and Mitigations

Is GitHub Copilot the best AI-assistant for Data Scientists?

What are the principles we can use to build LLM-powered software that is actually good enough to put in the hands of production customers? - humanlayer/12-factor-agents

From reading the title I was nervous that this might involve automating the initial response to a user support query in an issue tracker with an LLM, but Carlton Gibson …

Cotypist: AI autocomplete for Mac. Type as fast as you think in any app. Save hours, reduce errors, and boost your productivity.

I made my AI think harder by making it argue with itself repeatedly. It works stupidly well. - PhialsBasement/Chain-of-Recursive-Thoughts

We asked some of the world’s foremost experts an impossible question. Amazingly, they answered.

Kimi-Audio, an open-source audio foundation model excelling in audio understanding, generation, and conversation - MoonshotAI/Kimi-Audio