2016

(NaturalHealth365) University of Maryland study finds HPV shots increase autonomic dysfunction risk by 23%, and that's not all.

(NaturalHealth365) New research reveals women with heart disease have 10% higher odds of aggressive breast cancer.

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https://peregrineroasters.comYour support makes all the difference. Every gift helps us continue teaching, equipping, and proclaiming biblical truth—for free...

In our final episode of this new series, Timothy Mahoney, Mori Michael Shelomo Bar Ron, and Dr. Pieter van der Veen close their important discussion about Mo...

How DMSO being mixed with numerous common medications creates a myriad of remarkable therapeutic possibilities

According to the Book of Daniel, this Israel/Iran War leads to the rise of the Antichrist. How is the current Ayatollah of Iran, hiding in a bunker, a "TimeM...

Joel Richardson is a New York York Times bestselling author, internationally recognized teacher, artist, and craftsman. His work has been featured on numerous radio, television, and news outlets. Thank you for coming to this channel. I hope that you enjoy each video update, learn more about what God is doing in our world, and share what you learn with others. Blessings!

This natural compound relieves pain, heals tissue, and treats countless “untreatable” conditions.

The new Jurassic World: Rebirth movie just came out. It depicts many different dinosaurs, but just how accurate are they? In this video, Joel Leineweber shar...

Please consider becoming a regular supporter of Joel Richardson Ministries: https://joelstrumpet.com/?page_id=8560

An interesting new article suggests value of creatine supplementation in Alzheimer's disease

Want better sleep, faster recovery, and peak performance? In this powerful episode of The Dr. Hyman Show, Dr. Mark Hyman sits down with human performance exp...

This short video was created in May of 2024. The things Gary Stearman and Bill Salus discussed concerning the current events in Iran at that time, we are sti...

#Parkinsons #TheParkinsonsPlan #EnvironmentalHealth #Neuroscience #PreventParkinsonsParkinson’s disease is rising faster than ever before — with 90,000 new U...

Low molecular weight fucoidan (LMWF), a depolymerized form, is known to possess superior bioactivities compared to its high molecular weight counterpa…

The data that shows the less appreciated and forgotten consequences of vaccination.

Link to the notes:  https://docs.google.com/document/d/1G0JYEOi1HyTzyT3RxAX8AbIZejyZyl_s/edit?usp=drivesdk&ouid=102430545303799711405&rtpof=true&sd=true C04-5-18

Ozempic works… until it doesn’t. Then your real problems begin.

The Immense Dangers of the GLP-1 drugs and the Scandalous Corruption That Led the FDA to Push Them Upon America

Henry B. Smith Jr. of Associates for Biblical Research is the guest on Let Us Reason and discusses the numerical divergences between the Masoretic Text, Sama...

(NaturalHealth365) Forever chemicals in pregnancy program children for teen hypertension. Learn how to protect your family.

Ulcerative colitis (UC), a chronic inflammatory bowel disease driven by gut dysbiosis, immune dysregulation, and oxidative stress, lacks universally effectiv...

This study investigates the anti-lung cancer activities of polysaccharides extracted from Laminaria japonica, focusing on their bioactive components a…

About 2600 years ago, the prophet Jeremiah predicted that in the latter days a disaster would happen in ELAM, which is in modern day SW IRAN. The details of ...

Israel is at the center of the End Times. So Jewish End Time beliefs influence what happens NEXT. And they are NOT what you EXPECT. They will impact how Jew...

Clean, speed up, and protect your PC with Spyzooka. Remove spyware, fix errors, and optimize performance—fast, easy, and effective!

Ezekiel 38 is a marquee prophetic event of the end times. Many of today's top experts think it could be the next prophecy to find fulfillment. But are they c...

Glioblastoma presents significant challenges in neuro-oncology due to its aggressive nature, drug resistance, and restrictions imposed by the blood–brain barrier. Ivermectin (IVM), known for its antiparasitic properties, has been highlighted as a promising treatment for tumors and an alternative therapy for glioma, although it exhibits low oral bioavailability. Therefore, we investigated the in vivo effect of IVM encapsulation in organic and inorganic nanosystems, first screened in vitro against different tumor cells and subsequently evaluated in vitro and in vivo glioma models. We produced IVM-loaded poly(ε-caprolactone) nanocapsules (IVM-NC) using the interfacial deposition method, and IVM-loaded nanostructured silica particles (IVM-MCM) by loading IVM into commercial MCM-41 silica using the incipient wetness method. IVM-NC had a nanometric size (190 nm), a unimodal size distribution (span <2), and a high encapsulation efficiency (100% at 1 mg/mL). IVM-MCM exhibited a well-organized hexagonal mesoporous structure and high drug loading (0.12 mg/mg). Nanoencapsulated IVM significantly reduced the viability of various cancer cell lines, particularly glioma cell lines, which led us to evaluate them in a preclinical glioma model. We implanted adult male Wistar rats with C6 cells. Intranasal delivery of IVM-NC (60 μg/rat/day for 10 days) resulted in a larger decrease in tumor size compared with the group treated with free IVM, along with histopathological improvements. Treatment with IVM-MCM did not decrease the tumor size. However, both treatments were well-tolerated, with no adverse effects on weight, biochemical, or hematological parameters, or lung histology. Furthermore, the effective equivalent dose of IVM (26 μg/kg) in the rat glioma model was lower than the approved human dose for parasitic infections. This study marks the first exploration of IVM delivery to the brain. In summary, nasal administration of nanoencapsulated IVM via nanocapsules presents a promising avenue for targeted therapy against glioblastoma, with potential implications for clinical translation.