COVID-19

Two new high-profile studies add to the increasingly worrisome picture of how even mild cases of COVID-19 can have detrimental effects on brain health.

A study found COVID-19 could be linked to onset cognitive impairment in patients 65 and older.

Researchers have discovered a mutation in the SARS-CoV-2 spike protein that enhances its ability to infect the central nervous system, potentially explaining neurological symptoms and “long COVID.”

New working paper is believed to be the first to link weaker memory and diminished ‘flexible thinking’ skills to the pandemic’s academic downturn.

Washington Post It’s more than four years since the first cases of covid-19 were identified — but many of its longer-term effects, including for those living with long covid, remain uncle…

Washington Post It’s more than four years since the first cases of covid-19 were identified — but many of its longer-term effects, including for those living with long covid, remain uncle…

Researchers have discovered that the SARS-CoV-2 spike protein persists in the brain and skull bone marrow for years after infection, potentially leading to chronic inflammation and neurodegenerative diseases. Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have uncovere

A significant number of patients who were admitted to hospital with covid-19 still experience substantial cognitive and psychiatric effects as much as three years later, a longitudinal study has found.1 Almost half of the study participants experienced moderate to severe depression, one in four reported moderate to severe anxiety, and four in 10 reported severe cognitive decline. One in nine had objective signs of severe cognitive deficits—equivalent to a loss of 10 IQ points—the research published in the Lancet Psychiatry found. However, the authors acknowledged a risk of selection bias, as the study had a low response rate, with only 19.2% of those invited choosing to take part. Researchers contacted 2469 of the participants in the Post-Hospitalisation Covid-19 study who had been discharged from one …

Anxiety, mood, and substance use disorders were most common, but the researchers also found worrying, if lower, rates of serious neurological complications, especially in patients who had been severely ill with Covid-19.

Nature Reviews Immunology - SARS-CoV-2 infection can lead to a diverse array of chronic symptoms, collectively termed ‘long COVID’. In this Review, Altmann and colleagues explore...

Post COVID-19 Condition, commonly known as long COVID, can affect anyone exposed to SARS-CoV-2, regardless of age or severity of original symptoms.

Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2 …

Post-acute infection syndromes may develop after acute viral disease1. Infection with SARS-CoV-2 can result in the development of a post-acute infection syndrome known as long COVID. Individuals with long COVID frequently report unremitting fatigue, post-exertional malaise, and a variety …

Nature Immunology - Roan et al. use Olink and single‐cell RNA sequencing (scRNA-seq) to show a dysregulated crosstalk between the cellular and humoral immune responses in individuals with...

Nature Immunology - Phetsouphanh and colleagues show that individuals with long COVID have persistent activation of the innate and adaptive immune system at 8 months after infection and define a...

COVID-19 and long COVID can have long-lasting effects on the immune system and immune cells, leaving people more vulnerable to future illness

Immunity debt — the idea that our immune systems become weak if we're not regularly exposed to pathogens — is a popular (and wrong) conception of how the body works

At the beginning of the fifth season of the television show Buffy the Vampire Slayer, we the audience are introduced to a character, Dawn, we have never seen before. Intriguingly, every character

Post-COVID-19 condition (also known as long COVID) is generally defined as symptoms persisting for 3 months or more after acute COVID-19. Long COVID c…

A new study finds the risks of developing long COVID declined over the first two years of the pandemic. But unvaccinated adults were more than twice as likely to get long COVID compared with those who were vaccinated.

This observational cohort study examines the symptoms experienced by children after SARS-CoV-2 infection and how these symptoms differ by age (6-11 years vs 12-17 years).

CYP have a fluctuating experience of cognitive impairment by 12-months post SARS-CoV-2-infection. Cognitive impairment is consistently correlated with poorer sleep, behavioural and emotional functioning over a 12-month period. Clinicians should be aware of cognitive impairment post-infection and its …

They don't experience the same symptoms as adults.