Covid19-Sources

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Kidney Outcomes in Long COVID : Journal of the American Society of Nephrology
Kidney Outcomes in Long COVID : Journal of the American Society of Nephrology
Results  Beyond the acute illness, 30-day survivors of COVID-19 exhibited a higher risk of AKI (aHR, 1.94; 95% CI, 1.86 to 2.04), eGFR decline ≥30% (aHR, 1.25; 95% CI, 1.14 to 1.37), eGFR decline ≥40% (aHR, 1.44; 95% CI, 1.37 to 1.51), eGFR decline ≥50% (aHR, 1.62; 95% CI, 1.51 to 1.74), ESKD (aHR, 2.96; 95% CI, 2.49 to 3.51), and MAKE (aHR, 1.66; 95% CI, 1.58 to 1.74). Increase in risks of post-acute kidney outcomes was graded according to the severity of the acute infection (whether patients were non-hospitalized, hospitalized, or admitted to intensive care). Compared with non-infected controls, 30-day survivors of COVID-19 exhibited excess eGFR decline (95% CI) of −3.26 (−3.58 to −2.94), −5.20 (−6.24 to −4.16), and −7.69 (−8.27 to −7.12) ml/min per 1.73 m2 per year, respectively, in non-hospitalized, hospitalized, and those admitted to intensive care during the acute phase of COVID-19 infection.
fsnestel·journals.lww.com·
Kidney Outcomes in Long COVID : Journal of the American Society of Nephrology
Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion | NEJM
Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion | NEJM
Nonetheless, our findings suggest that the risk of spontaneous abortion after mRNA Covid-19 vaccination either before conception or during pregnancy is consistent with the expected risk of spontaneous abortion; these findings add to the accumulating evidence about the safety of mRNA Covid-19 vaccination in pregnancy.
fsnestel·nejm.org·
Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion | NEJM
Superior neutralizing response after first versus second SARS‐CoV‐2 infection in fully vaccinated individuals
Superior neutralizing response after first versus second SARS‐CoV‐2 infection in fully vaccinated individuals
Our results show that the first episode of SARS-CoV-2 infection induces a significant increase in neutralizing titers in triple vaccinated individuals and that previous SARS-CoV-2 infection compromise significantly the neutralization response induced by reinfection, even by divergent SARS-CoV-2 variants and at least up to 2 years postinfection, suggesting a fundamental limitation in inducing effective booster through the intranasal route in previously infected individuals.
fsnestel·onlinelibrary.wiley.com·
Superior neutralizing response after first versus second SARS‐CoV‐2 infection in fully vaccinated individuals