Covid19-Sources

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Effect of Nirmatrelvir-Ritonavir on Short- and Long-term Adverse Outcomes From COVID-19 Among Patients With Kidney Disease: A Propensity Score–Matched Study | Open Forum Infectious Diseases | Oxford Academic
Effect of Nirmatrelvir-Ritonavir on Short- and Long-term Adverse Outcomes From COVID-19 Among Patients With Kidney Disease: A Propensity Score–Matched Study | Open Forum Infectious Diseases | Oxford Academic
fsnestel·academic.oup.com·
Effect of Nirmatrelvir-Ritonavir on Short- and Long-term Adverse Outcomes From COVID-19 Among Patients With Kidney Disease: A Propensity Score–Matched Study | Open Forum Infectious Diseases | Oxford Academic
Frontiers | Potential protective role of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) in COVID-19
Frontiers | Potential protective role of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) in COVID-19
The COVID-19 pandemic has prompted a quest to understand why certain individuals remain uninfected or asymptomatic despite repetitive exposure to SARS-CoV-2. Here, we focused on six exposed females residing with their symptomatic and reinfected SARS-CoV-2 PCR-positive COVID-19 partners. Peripheral blood mononuclear cell samples from couples were analysed for poly (I:C)-induced mRNA expression of type I/III interferons and interferon-stimulated genes (ISGs). Remarkably, we found a significant upregulation of the ISG interferon-inducible protein with tetrapeptide repeats 3 (IFIT3) gene exclusively in exposed uninfected or asymptomatic females, suggesting a potential role in protective immunity against symptomatic COVID-19.
fsnestel·frontiersin.org·
Frontiers | Potential protective role of interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) in COVID-19