Dr Graham Lloyd-Jones on Twitter
Covid19-Sources
Spike in severe illness caused by strep A bacteria is 'global phenomenon' — including in Canada | CBC News
SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
Numerous viruses use specialized surface molecules called fusogens to enter host cells. Many of these viruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can infect the brain and are associated with severe neurological symptoms through poorly understood mechanisms. We show that SARS-CoV-2 infection induces fusion between neurons and between neurons and glia in mouse and human brain organoids. We reveal that this is caused by the viral fusogen, as it is fully mimicked by the expression of the SARS-CoV-2 spike (S) protein or the unrelated fusogen p15 from the baboon orthoreovirus. We demonstrate that neuronal fusion is a progressive event, leads to the formation of multicellular syncytia, and causes the spread of large molecules and organelles. Last, using Ca2+ imaging, we show that fusion severely compromises neuronal activity. These results provide mechanistic insights into how SARS-CoV-2 and other viruses affect the nervous system, alter its function, and cause neuropathology.
Could fused neurons explain COVID-19’s ‘brain fog’?
🌍Derfel The Crackpot 🌍 on Twitter
Neutralising immunity to omicron sublineages BQ.1.1, XBB, and XBB.1.5 in healthy adults is boosted by bivalent BA.1-containing mRNA vaccination and previous Omicron infection
Protective immunity of SARS-CoV-2 infection and vaccines against medically attended symptomatic omicron BA.4, BA.5, and XBB reinfections in Singapore: a national cohort study
Emma Wall on Twitter
Single-cycle SARS-CoV-2 vaccine elicits high protection and sterilizing immunity in hamsters
Vipin M. Vashishtha on Twitter
Nathan Cole ⚕️ @mastodontech.de on Twitter
Statistikdatabaser - Diagnoser - Val
Dream-enactment disorder rose up to fourfold during pandemic, study finds
Myocarditis in SARS-CoV-2 infection vs. COVID-19 vaccination: A systematic review and meta-analysis
Conclusion: In this systematic review and meta-analysis, we found that the risk of myocarditis is more than seven fold higher in persons who were infected with the SARS-CoV-2 than in those who received the vaccine. These findings support the continued use of mRNA COVID-19 vaccines among all eligible persons per CDC and WHO recommendations.
Respiratory sequelae of COVID-19: pulmonary and extrapulmonary origins, and approaches to clinical care and rehabilitation
Estimation of Excess Mortality in Germany During 2020-2022
Jean Fisch on Twitter
Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study
Family resemblance: How T cells could fight many coronaviruses at once
Biological mechanisms underpinning the development of long COVID
COVID19 DASHBOARD ANIMALS GLOBAL
Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose
Japanischer Professor warnt vor krebsauslösender Gensequenz in Covid-Impfstoffen
Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs
Two Cases of Neurological Complications After mRNA Vaccination for COVID-19 (P1-1.Virtual)
Covid caused brain damage in 2 babies infected during pregnancy, study shows
Reinfection by SARS-CoV-2 by divergent Omicron sublineages, 16 days apart
COVID-19 vaccines did not cause an increase in cancer deaths
Onkologen empfehlen Impfung - «Turbokrebs» ist kein medizinischer Begriff
The functional and structural changes in the hippocampus of COVID-19 patients