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T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy - PubMed
T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy - PubMed
FM patients show a Th1 signature and the activation of this subset is modulated by HBOT.
Objectives: Hyperbaric oxygen therapy (HBOT) has been used as treatment for different clinical conditions, including fibromyalgia (FM). HBOT modulates brain activity, ameliorates chronic pain and modifies the ratio of immune cells. Clinical studies have provided evidence that FM is associated with immune system dysregulation.
Results: Our results confirm the participation of immune system in the pathogenesis of FM and highlight the impact of HBOT treatment, with particular regard to the changes on proinflammatory cytokines production by CD4 T cells subsets. Conclusions: FM patients show a Th1 signature and the activation of this subset is modulated by HBOT.
#fibromyalgia#immune response#Th1 response#research#microglial cells
·pubmed.ncbi.nlm.nih.gov·
T helper 1 response is correlated with widespread pain, fatigue, sleeping disorders and the quality of life in patients with fibromyalgia and is modulated by hyperbaric oxygen therapy - PubMed
T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives
T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives
Fibromyalgia is one of the most important “rheumatic” disorders, after osteoarthritis. The etiology of the disease is still not clear. At the moment, the most defined pathological mechanism is the alteration of central pain pathways, and ...
#fibromyalgia#research#immune#t cells#microglial cells
·ncbi.nlm.nih.gov·
T Cell Subpopulations in the Physiopathology of Fibromyalgia: Evidence and Perspectives
The widespread myofascial pain of fibromyalgia is sympathetically maintained and immune mediated
The widespread myofascial pain of fibromyalgia is sympathetically maintained and immune mediated

Summary of what might really be causing fibromyalgia?

#fibromyalgia#pain#immune#myofascial inflammation#fascia#biopsies#oxidative stress markers#collagen#sympathetic nervous system#nervous system#autoantibodies#autoimmune#dorsal root ganglion#glial cells#microglial#microglial cells#central sensitization#myofascial release#B-cell depletion#Treg expanders#MCP-1#fractalkine antagonists#research#Dr. Ginevra Liptan
·bodyworkmovementtherapies.com·
The widespread myofascial pain of fibromyalgia is sympathetically maintained and immune mediated
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
Interesting that Metaxalone has this effect, and it works well for fibromyalgia. More suggestion that there is an autoimmune component.
#neuroinflammation#microglial#microglial cells#autoimmune#nerve damage#nervous system#myofascial inflammation#metaxalone#CNS#sympathetic nervous system#fibromyalgia#research#treatment#rehabilitation
·ncbi.nlm.nih.gov·
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells