The widespread myofascial pain of fibromyalgia is sympathetically maintained and immune mediated
Summary of what might really be causing fibromyalgia?
What your doctor DOESN'T know about fibromyalgia pain is hurting you!
Immune system, sympathetic nervous system and myofascial abnormalities
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
Interesting that Metaxalone has this effect, and it works well for fibromyalgia. More suggestion that there is an autoimmune component.