Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation - PubMed
Neuroinflammation from brain glial activation in fibromyalgia
Prednisone helping fibromyalgia pain
In my case, personally speaking, prednisone gets rid of the pain.
What your doctor DOESN'T know about fibromyalgia pain is hurting you!
Immune system, sympathetic nervous system and myofascial abnormalities
Hormonal Health and Wellness Inflammation & Low Dose Naltrexone in Cross Roads, TX | Cross Roads Hormonal Health & Wellness
Low Dose Naltrexone helping fibromyalgial pain.
Modafinil goes well beyond addressing fatigue.
I take Nuvigil (armodafinil) which is an isomer of Provigil (modafinil), which was shown to reduce neuroinflammation. Nuvigil takes away a lot of my pain.
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Neuroinflammation being a factor, plus modafinil use. In my case, armodafinil works well for pain (Nuvigil).
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Is Fibromyalgia an Autoimmune Disease?
It has an autoimmune component. "that several autoantibodies were unusually high in people with FM"
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
Interesting that Metaxalone has this effect, and it works well for fibromyalgia. More suggestion that there is an autoimmune component.