Combined use of Pregabalin and Memantine in Fibromyalgia Syndrome Treatment: A Novel Analgesic and Neuroprotective Strategy?
Memantine (an Alzheimer’s drug) slows loss of grey matter in brains of people with fibromyalgia. Also decreases pain.
New Treatment Target for Fibromyalgia: Inflammation in the Brain
Neuroinflammation in the brain as a therapeutic target
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain