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Repetitive transcranial magnetic stimulation in patients with fibromyalgia: A protocol for systematic review and network meta-analysis
Repetitive transcranial magnetic stimulation in patients with fibromyalgia: A protocol for systematic review and network meta-analysis
Transcranial magnetic stimulation effective at relieving fibromyalgia pain.
Repetitive transcranial magnetic stimulation (rTMS) effectively relieves pain intensity in patients with fibromyalgia. The frequency and target site of rTMS have significant roles in therapy effectiveness.
·ncbi.nlm.nih.gov·
Repetitive transcranial magnetic stimulation in patients with fibromyalgia: A protocol for systematic review and network meta-analysis
Isometric exercise has opposite effects on central pain mechanisms in fibromyalgia patients compared to normal controls - PubMed
Isometric exercise has opposite effects on central pain mechanisms in fibromyalgia patients compared to normal controls - PubMed

Aerobic exercise increases fibromyalgia pain. Isometric exercise improved it.

In contrast, fibromyalgia (FM) subjects' experimental pain ratings increase after aerobic exercise, suggestive of abnormal pain modulation.
·pubmed.ncbi.nlm.nih.gov·
Isometric exercise has opposite effects on central pain mechanisms in fibromyalgia patients compared to normal controls - PubMed
Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review
Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review

Specifically WA-ON, ceramic-coated

3.1.2. Fibromyalgia Three Randomized controlled trials and one observational study focused on fibromyalgia (FM). These studies were published between 2007 and 2019 and included 219 patients. All studies reported significant pain and FM symptoms reduction and quality of life improvement. In particular, fabrics coated with bioceramics could decrease FM-associated pain and burden in female patients by 21% in the VAS and FIQ assessment scales [17]. WAON therapy (soothing warmth therapy) was associated with an even greater improvement of FM symptoms assessed by both scales (52.7% in VAS, 34.6% in FIQ) in both male and female patients [16]. Similar results were reported with the use of AE and FIR [16] and mild water-filtered near-infrared whole-body hyperthermia (NI-WBH) [15] in both male and female patients. The latter appeared as a beneficial addition to standard multimodal rehabilitation (MR) sessions [15]. FIR treatment sessions were provided for 2–6 weeks [16,18], and patients were monitored for a time period ranging between 2 weeks and 6 months [15]. The reported relief was maintained during the monitoring period [18] or was significant within the first 6 weeks post-treatment [15].
·ncbi.nlm.nih.gov·
Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review
Dietary supplementation evening primrose oil improve symptoms of fibromyalgia syndrome
Dietary supplementation evening primrose oil improve symptoms of fibromyalgia syndrome
Evening primrose oil (EPO) is widely used as a dietary supplement from which beneficial effects have been reported in rheumatic and arthritic conditio…
oxidative stress hypothesis
Although very few studies have shown elevated cytokine levels in FMS, the data available suggest that a high chemokine level may play a causative role in this disease
A review of the FMS literature and related studies suggest that IL-1, IL-6 and IL-8 are deregulated in the syndrome. Therefore, therapies directed against these cytokines and others may be of potential importance in the management of FMS
·sciencedirect.com·
Dietary supplementation evening primrose oil improve symptoms of fibromyalgia syndrome
Carnitine Palmitoyl Transferase Deficiency in a University Immunology Practice - PubMed
Carnitine Palmitoyl Transferase Deficiency in a University Immunology Practice - PubMed

Many participants had fibromyalgia in this study, and had fatigue and exercise intolerance. Study points to underlying metabolic disease.

·pubmed.ncbi.nlm.nih.gov·
Carnitine Palmitoyl Transferase Deficiency in a University Immunology Practice - PubMed
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain
·pubmed.ncbi.nlm.nih.gov·
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Neuroinflammation being a factor, plus modafinil use. In my case, armodafinil works well for pain (Nuvigil).
·frontiersin.org·
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
Interesting that Metaxalone has this effect, and it works well for fibromyalgia. More suggestion that there is an autoimmune component.
·ncbi.nlm.nih.gov·
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells