Modafinil goes well beyond addressing fatigue.
I take Nuvigil (armodafinil) which is an isomer of Provigil (modafinil), which was shown to reduce neuroinflammation. Nuvigil takes away a lot of my pain.
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Neuroinflammation being a factor, plus modafinil use. In my case, armodafinil works well for pain (Nuvigil).
MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells
Interesting that Metaxalone has this effect, and it works well for fibromyalgia. More suggestion that there is an autoimmune component.
Immunometabolic modulatory role of naltrexone in micro glial cells
Suggests fibromyalgia has An autoimmune component