Modafinil goes well beyond addressing fatigue.
I take Nuvigil (armodafinil) which is an isomer of Provigil (modafinil), which was shown to reduce neuroinflammation. Nuvigil takes away a lot of my pain.
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Neuroinflammation being a factor, plus modafinil use. In my case, armodafinil works well for pain (Nuvigil).
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Is Fibromyalgia an Autoimmune Disease?
It has an autoimmune component. "that several autoantibodies were unusually high in people with FM"