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Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]
Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]
Norepinephrine-evoked pain was seen in 80 % of FM patients (95% confidence intervals 56.3 – 94.3%), in 30 % of rheumatoid arthritis patients and in 30 % of healthy controls (95% confidence intervals 11.9 – 54.3) (p < 0.05). Intensity of norepinephrine-evoked pain was greater in FM patients (mean ± SD 2.5 ± 2.5) when compared to rheumatoid arthritis patients (0.3 ± 0.7), and healthy controls (0.3 ± 0.8) p < 0.0001.
#fibromyalgia#norepinephrine#pain#research
·ncbi.nlm.nih.gov·
Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
This would explain why the isomer of modafinil that I take, armodafinil, greatly reduces my pain
#immune#immunomodulation#autoimmune#modafinil#neuroinflammation#dopamine#norepinephrine#fibromyalgia#brain#CNS#GABA#pain#research#treatment#rehabilitation
·pubmed.ncbi.nlm.nih.gov·
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders - PubMed
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation
Neuroinflammation being a factor, plus modafinil use. In my case, armodafinil works well for pain (Nuvigil).
#caffeine#fibromyalgia#modafinil#neuroinflammation#dopamine#norepinephrine#GABA#brain#autoimmune#immune#immunomodulation#research#treatment#rehabilitation
·frontiersin.org·
Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation