Covid and Autoimmune Disease

Covid and Autoimmune Disease

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MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)
MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)
🚨A distinct pattern of Melanoma Differentiation-Associated protein-5-autoimmunity cases surged contemporaneously with circulation of the SARS-COV-2 virus during COVID19. Bioinformatic insights suggest a shared immunopathology with known autoimmune lung disease mechanisms.
·thelancet.com·
MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)
Laura Miers on Twitter
Laura Miers on Twitter

Detailed thread on Twitter covering autoimmune encephalitis "We may be entering an era of heightened autoimmune encephalitis. These occurrences may be post-infectious in nature at this point of the pandemic."

·twitter.com·
Laura Miers on Twitter
High risk of autoimmune diseases after COVID-19
High risk of autoimmune diseases after COVID-19

Three new studies give us good estimates of a heightened risk of auto-immune disease after COVID-19 infection. Risk increases of between 20 and 40%

This data franks earlier evidence about lots of self-directed antibodies seen in people post-COVID

·nature.com·
High risk of autoimmune diseases after COVID-19
High risk of autoimmune diseases after COVID-19
High risk of autoimmune diseases after COVID-19
"Two studies that use large cohorts now highlight that SARS-CoV-2 infection is linked to a substantially increased risk of developing a diverse spectrum of new-onset autoimmune diseases."
·nature.com·
High risk of autoimmune diseases after COVID-19
Pmc9830133
Pmc9830133
RISK of AUTOIMMUNE DISEASES in patients with COVID-19: A retrospective cohort study
·ncbi.nlm.nih.gov·
Pmc9830133
A Comprehensive Review of COVID-19–Associated Endocrine Manifestations
A Comprehensive Review of COVID-19–Associated Endocrine Manifestations
As result of the COVID-19 infections, "Thyroid dysfunction with subacute thyroiditis, Graves’ disease & hypothyroidism caused by primary autoimmune thyroiditis has been reported. Pancreatic damage leads to type 1 DM because of the autoimmune nature of the disease and type 2 DM because of postinflammatory insulin resistance."
·ncbi.nlm.nih.gov·
A Comprehensive Review of COVID-19–Associated Endocrine Manifestations
laurie allee on Twitter
laurie allee on Twitter
“Recent research suggests people with long Covid are more likely to have markers of autoimmune disease in their blood a year after infection.”
·twitter.com·
laurie allee on Twitter
Mw on Twitter
Mw on Twitter

Detailed Twitter thread: IBD is an autoimmune condition, which studies have shown increases a person’s chances of Long Covid. Now doctors are seeing both de novo IBD after Covid and worsening of existing IBD. (see this thread). More research is needed. Another reason for high grade mask & ventilation.

·twitter.com·
Mw on Twitter
Radiological images confirm 'COVID-19 can cause the body to attack itself': Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain
Radiological images confirm 'COVID-19 can cause the body to attack itself': Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain
"We've realized that the COVID virus can trigger the body to attack itself in different ways, which may lead to rheumatological issues that require lifelong management,"
·sciencedaily.com·
Radiological images confirm 'COVID-19 can cause the body to attack itself': Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain
New Onset of Autoimmune Diseases Following COVID-19 Diagnosis
New Onset of Autoimmune Diseases Following COVID-19 Diagnosis
"There is growing evidence that COVID-19 can lead to a dysregulation of the immune system with the development of autoimmune phenomena...immune dysregulation ranges from the production of autoantibodies to the onset of rheumatic autoimmune disease."
·ncbi.nlm.nih.gov·
New Onset of Autoimmune Diseases Following COVID-19 Diagnosis