Megakaryocytes Under Siege: Another Hidden Culprit Behind COVID-19 Complications
Megakaryocytes Under Siege: Another Hidden Culprit Behind COVID-19 Complications
Analysis thread on Twitter SARS-Cov-2 causes osteoporosis as a consequence of monocyte derived macrophages differentiating into osteoclasts, which participate in bone remodeling. This has been known since this article.
"SARS-CoV-2 can cause quick and significant bone loss—even when infections appear to be mild..."
Mice infected with the virus: Lost 25% of bone mass within 2 weeks Had 63% increase in osteoclasts--cells that cause bone to break down.