Covid and Brain Damage

Covid and Brain Damage

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Thread by @JamesThrot on Thread Reader App
Thread by @JamesThrot on Thread Reader App

“Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵”

Let’s talk about COVID, brain damage & society. Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences? This thread is for the skeptics. I’m a neurologist, stay with me 🧵
#Brain#Covid Isn't Over#Post-Acute Conditions#consequences#frontal lobe#brain dysfunction#cognition#cognitive decline#Long Covid#neurological#Post-Acute Sequelae of COVID-19#Cognitive Impairment#white matter#grey matter shrinkage#olfactory damage#working memory#Discussion#analysis#James Throt
·threadreaderapp.com·
Thread by @JamesThrot on Thread Reader App
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
#cognitive decline#memory#long covid#cognition#Cognitive Impairment#Brain Fog#Long Covid#Post-Acute Conditions#Brain#neurological
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Thread by @ZdenekVrozina on Thread Reader App
Thread by @ZdenekVrozina on Thread Reader App

“Long COVID can injure the brain - and persistent autoimmunity could be a major driver. A study links persistent AT1 receptor autoantibodies (AT1-AA) with neuroaxonal injury and cognitive symptoms. Here’s what it means🧵”

Long COVID can injure the brain - and persistent autoimmunity could be a major driver. A study links persistent AT1 receptor autoantibodies (AT1-AA) with neuroaxonal injury and cognitive symptoms. Here’s what it means🧵
#Long Covid#autoimmunity#brain injury#autoantibodies#Immune system#Post-Acute Conditions#autoimmune#Discussion#analysis#biomarkers of Covid brain injury#neurological
·threadreaderapp.com·
Thread by @ZdenekVrozina on Thread Reader App
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
“Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.”
Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.
#autoimmunity#neurological#Post-Acute Conditions#Long Covid#Immune system#brain#Neuroaxonal damage
·frontiersin.org·
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Cognitive decline is a common symptom of post-COVID-19 syndrome. However, the mechanisms underlying this deficit remain poorly understood. This study aims to investigate the relationship between brain metabolic and neurophysiological alteration patterns in patients with persistent subjective cognitive decline after mild COVID-19 using joint FDG-PET and EEG analyses.
Cognitive decline is a common symptom of post-COVID-19 syndrome. However, the mechanisms underlying this deficit remain poorly understood. This study aims to investigate the relationship between brain metabolic and neurophysiological alteration patterns in patients with persistent subjective cognitive decline after mild COVID-19 using joint FDG-PET and EEG analyses.
#Cognitive Impairment#brain changes#cognitive decline#hypometabolism#Post-Acute Conditions#brain dysfunction#brain#neuroimaging#EEG slowing#cognition
·nature.com·
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Thread by @Becca_Roth on Thread Reader App
Thread by @Becca_Roth on Thread Reader App
“Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen”
Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen
#Long Covid#Post-Acute Conditions#anecdote#disability#young people#cognition#cognitive decline#consequences#Discussion#Memory#working memory#word retrieval problems#reaction time deficits#brain abnormalities#brain fog#media and government lies
·threadreaderapp.com·
Thread by @Becca_Roth on Thread Reader App
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection

“COVID-19 survivors were at higher adjusted risk of mortality, major adverse cardiovascular events, fatigue, sleep disturbance, and dyspnea. • COVID-19 may be a risk factor for onset of symptoms and adverse events in patients with neurological conditions”

COVID-19 survivors were at higher adjusted risk of mortality, major adverse cardiovascular events, fatigue, sleep disturbance, and dyspnea.•COVID-19 may be a risk factor for onset of symptoms and adverse events in patients with neurological conditions
#Neurological Complications#Post-Acute Conditions#neurological#Long Covid
·sciencedirect.com·
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection
Lacking focus, tired always? Could be brain fog
Lacking focus, tired always? Could be brain fog

“Brain fog may gradually evolve into a slight memory problem, difficulty finding the right word for things, objects, situations and then registering new information.”

A widely held notion is that SARS2 activates our immune systems, causing an inflammatory response in the brain.

#Memory#cognition#Long Covid#brain fog#Cognitive Decline#Post-Acute Conditions#Cognitive Impairment#cognitive decline#Neuroinflammation
·newindianexpress.com·
Lacking focus, tired always? Could be brain fog
Dad, 41, Diagnosed with Alzheimer's: 'You Feel Guilty That You're Doing That to the Kids'
Dad, 41, Diagnosed with Alzheimer's: 'You Feel Guilty That You're Doing That to the Kids'

“Dad, 41, Diagnosed with Alzheimer's: 'You Feel Guilty That You're Doing That to the Kids' Fraser is sharing his symptoms — and what he’s learned about the disease — on his YouTube channel”

Dad, 41, Diagnosed with Alzheimer's: 'You Feel Guilty That You're Doing That to the Kids' Fraser is sharing his symptoms — and what he’s learned about the disease — on his YouTube channel
#dementia#Alzheimers#anecdote#Cognitive Decline#memory loss#neurological#early-onset Alzheimer's#Post-Acute Conditions#Memory#working memory#risks#young people
·people.com·
Dad, 41, Diagnosed with Alzheimer's: 'You Feel Guilty That You're Doing That to the Kids'
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
#Long Covid#Cognitive Impairment#mental health#neurological#Cognitive Decline#Post-Acute Conditions#Memory#memory loss#working memory#fatigue#emotional challenges#Mental Health
·bmcneurol.biomedcentral.com·
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Unusual Post–COVID-19 Presentation With Tetraventricular Hydrocephalus | Neurology Clinical Practice
Unusual Post–COVID-19 Presentation With Tetraventricular Hydrocephalus | Neurology Clinical Practice
“COVID-19 infection is suggested as one of the causes for hydrocephalus (HCP) of unknown etiology. “
COVID-19 infection is suggested as one of the causes for hydrocephalus (HCP) of unknown etiology.
#Normal Pressure Hydrocephalus#Brain#Post-Acute Conditions#brain#neurological
·neurology.org·
Unusual Post–COVID-19 Presentation With Tetraventricular Hydrocephalus | Neurology Clinical Practice
Normal pressure hydrocephalus associated with COVID-19 infection: a case report
Normal pressure hydrocephalus associated with COVID-19 infection: a case report
“Other infections such as syphilis, cryptococcosis and Lyme disease have been associated with NPH. Possible mechanisms for NPH after COVID include disruption of choroid plexus cells by direct viral invasion or as a result of neuroinflammation and cytokine release and hypercoagulability leading to venous congestion and abnormalities of CSF flow.”
Other infections such as syphilis, cryptococcosis and Lyme disease have been associated with NPH. Possible mechanisms for NPH after COVID include disruption of choroid plexus cells by direct viral invasion or as a result of neuroinflammation and cytokine release and hypercoagulability leading to venous congestion and abnormalities of CSF flow.
#Brain#Post-Acute Conditions#Normal Pressure Hydrocephalus
·pmc.ncbi.nlm.nih.gov·
Normal pressure hydrocephalus associated with COVID-19 infection: a case report