Found 61 bookmarks
Newest
Thread by @JamesThrot on Thread Reader App
Thread by @JamesThrot on Thread Reader App

“Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵”

Let’s talk about COVID, brain damage & society. Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences? This thread is for the skeptics. I’m a neurologist, stay with me 🧵
#Brain#Covid Isn't Over#Post-Acute Conditions#consequences#frontal lobe#brain dysfunction#cognition#cognitive decline#Long Covid#neurological#Post-Acute Sequelae of COVID-19#Cognitive Impairment#white matter#grey matter shrinkage#olfactory damage#working memory#Discussion#analysis#James Throt
·threadreaderapp.com·
Thread by @JamesThrot on Thread Reader App
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
#cognitive decline#memory#long covid#cognition#Cognitive Impairment#Brain Fog#Long Covid#Post-Acute Conditions#Brain#neurological
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Thread by @ZdenekVrozina on Thread Reader App
Thread by @ZdenekVrozina on Thread Reader App

“Long COVID can injure the brain - and persistent autoimmunity could be a major driver. A study links persistent AT1 receptor autoantibodies (AT1-AA) with neuroaxonal injury and cognitive symptoms. Here’s what it means🧵”

Long COVID can injure the brain - and persistent autoimmunity could be a major driver. A study links persistent AT1 receptor autoantibodies (AT1-AA) with neuroaxonal injury and cognitive symptoms. Here’s what it means🧵
#Long Covid#autoimmunity#brain injury#autoantibodies#Immune system#Post-Acute Conditions#autoimmune#Discussion#analysis#biomarkers of Covid brain injury#neurological
·threadreaderapp.com·
Thread by @ZdenekVrozina on Thread Reader App
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
“Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.”
Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.
#autoimmunity#neurological#Post-Acute Conditions#Long Covid#Immune system#brain#Neuroaxonal damage
·frontiersin.org·
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Thread by @Becca_Roth on Thread Reader App
Thread by @Becca_Roth on Thread Reader App
“Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen”
Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen
#Long Covid#Post-Acute Conditions#anecdote#disability#young people#cognition#cognitive decline#consequences#Discussion#Memory#working memory#word retrieval problems#reaction time deficits#brain abnormalities#brain fog#media and government lies
·threadreaderapp.com·
Thread by @Becca_Roth on Thread Reader App
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection

“COVID-19 survivors were at higher adjusted risk of mortality, major adverse cardiovascular events, fatigue, sleep disturbance, and dyspnea. • COVID-19 may be a risk factor for onset of symptoms and adverse events in patients with neurological conditions”

COVID-19 survivors were at higher adjusted risk of mortality, major adverse cardiovascular events, fatigue, sleep disturbance, and dyspnea.•COVID-19 may be a risk factor for onset of symptoms and adverse events in patients with neurological conditions
#Neurological Complications#Post-Acute Conditions#neurological#Long Covid
·sciencedirect.com·
Long-term outcomes of patients with a pre-existing neurological condition after SARS-CoV-2 infection
Lacking focus, tired always? Could be brain fog
Lacking focus, tired always? Could be brain fog

“Brain fog may gradually evolve into a slight memory problem, difficulty finding the right word for things, objects, situations and then registering new information.”

A widely held notion is that SARS2 activates our immune systems, causing an inflammatory response in the brain.

#Memory#cognition#Long Covid#brain fog#Cognitive Decline#Post-Acute Conditions#Cognitive Impairment#cognitive decline#Neuroinflammation
·newindianexpress.com·
Lacking focus, tired always? Could be brain fog
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
#Long Covid#Cognitive Impairment#mental health#neurological#Cognitive Decline#Post-Acute Conditions#Memory#memory loss#working memory#fatigue#emotional challenges#Mental Health
·bmcneurol.biomedcentral.com·
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
“Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.”
Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.
#Long Covid#Post-Acute Conditions#brain#neuroimaging#hypometabolism#Cognitive Impairment#neurological
·link.springer.com·
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
#Ears#Post-Acute Conditions#Auditory System#Long Covid#Brain#PASC#neurological#long covid#hearing loss#tinnitus#Fatigue#ANA test#Depression#cognitive decline
·nature.com·
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19

This analysis is supported by numerous videos and illustrations.

#Brain#Long Covid#Neuroinflammation#Post-Acute Conditions#brain injury#meninges#neurologic changes#neurological#spike protein#skull
·cell.com·
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
#Brain#Brain shrinkage#brain atrophy#Long Covid#Post-Acute Conditions#cognitive decline#cognition#organ damage
·academic.oup.com·
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
“Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review”
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
#Small Fiber Neuropathy#Dysautonomia#Internal Tremor#Long Covid#Post-Acute Conditions#neurological
·mdpi.com·
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
#Brain#Cognition#cognitive decline#Cognitive decline#Brain fog#Neuroinflammation#Post-Acute Conditions#Long Covid#organ damage
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
“Using the golden hamster as a model, we provide further evidence that SARS-CoV-2 is neuroinvasive and can persist in the central nervous system, as we found viral RNA and replicative virus in the brainstem after 80 days of infection.”
#Long Covid#Brain#Post-Acute Conditions#Neurodegenerative#Brainstem#Hamster Model#Viral Persistence#depression#memory loss#memory#central nervous system#anxiety
·biorxiv.org·
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics

Older adults recovering from COVID-19 face a 58% higher risk of developing dementia compared to those uninfected, with rates peaking 12 months post-infection.

Study reviewed 11 studies, 940k cases, 6.8M controls.

#dementia#cognitive decline#long covid#post-acute conditions#alzheimers#memory#aging#older adults
·bmcgeriatr.biomedcentral.com·
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics