Covid and Brain Damage
"Covid study finds millions have long-term smell or taste problems
Researchers say about 5% of infected adults may develop long-lasting changes to sense of smell or taste"
Brain damage after even mild Covid in kids: Omicron is much better at invading children's noses, predicts memory issues. "Severity of smell dysfunction after infection may be a better predictor of long-term cognitive impairment than severity of COVID-19"
"COVID Virus May Tunnel through Nanotubes from Nose to Brain
Nanotubes may provide a cunning answer to the mystery of how the virus that causes COVID infects neurons and produces long-lasting neurological symptoms"
Thread on Twitter: How might even mild respiratory #COVID infection affect the brain? Using a mouse model of mild SARS-CoV-2 infection limited to the respiratory system, we found elevation of CNS cytokines/chemokines and white matter-specific microglial reactivity. 3/
29 months of #LongCovid after a "mild" onset. Here are 3 of my 4 inoperable #brainAneurysms, lesions, volume loss, & brain damage after strokes caused by Covid. #longcovidbraindamage #stroke #covidbraindamage
How #SARSCoV2 infects/affects brain astrocytes https://pnas.org/doi/10.1073/pnas.2122236119 @PNASNews by @Andrews_MG
@tmturkee
@TheOttolab
@Kriegsteinlab and colleagues
"COVID Brain Problems May Stem From Attack on Endothelial Cells — Findings could have implications for treating long COVID"
UK researchers scanned the brains of 400 people before and after mild covid, compared them with controls and found:
- greater reduction in grey matter thickness
- greater reduction in global brain size
- greater cognitive decline
- greater change to primary olfactory cortex
Covid linked to significant brain shrinkage: "Even a mild COVID-19 infection can change the brain. People infected had a greater reduction in brain volume and performed worse on cognitive tests than those who did not contract COVID-19."
According to a systematic review on the COVID-19 survivors, "Seventy-nine percent of COVID-19 survivors at 1 months and 75% at 3- and 6-month follow-up showed cognitive impairment.."
3 in 4 is a quite high ratio.
COVID cognitive decline more widespread than thought say researchers at Australia's first long-COVID clinic Some sort of cognitive decline was recorded in almost all of the participants, regardless of the severity of the initial infection.
Comprehensive thread on Twitter 1/36 Update of the covid and the brain talk I recently gave to Drs at Select Medical Better quality figures More on references to look up: Lancet, NEJM, Nature, Neurology, etc Some new material dispersed and at end Some thoughts on possible treatments (not my expertise)
Excellent study from Oxford💥💥 This is the first report describing deficits in sustained attention & episodic memory amongst mildly-affected #COVID19 survivors long after the acute illness, in people who were not complaining of long-COVID symptoms