"Instead of disease severity, loss of smell seems a more promising avenue for predicting who develops persistent cognitive changes after SARS-CoV-2 infection."
Loss Of Smell Linked To Long Term Covid Cognitive Impairment
Attention medics. Does your patient have new-onset psychosis? hallucinations? personality changes post Covid?
They have neuro inflammation Encephalitis is not uncommon in #LongCovid, esp in the first months post infection. Psych is not appropriate. #MedTwitter #MedEd #TeamGP
"Covid study finds millions have long-term smell or taste problems
Researchers say about 5% of infected adults may develop long-lasting changes to sense of smell or taste"
Brain damage after even mild Covid in kids: Omicron is much better at invading children's noses, predicts memory issues. "Severity of smell dysfunction after infection may be a better predictor of long-term cognitive impairment than severity of COVID-19"
"COVID Virus May Tunnel through Nanotubes from Nose to Brain
Nanotubes may provide a cunning answer to the mystery of how the virus that causes COVID infects neurons and produces long-lasting neurological symptoms"
Thread on Twitter: How might even mild respiratory #COVID infection affect the brain? Using a mouse model of mild SARS-CoV-2 infection limited to the respiratory system, we found elevation of CNS cytokines/chemokines and white matter-specific microglial reactivity. 3/
29 months of #LongCovid after a "mild" onset. Here are 3 of my 4 inoperable #brainAneurysms, lesions, volume loss, & brain damage after strokes caused by Covid. #longcovidbraindamage #stroke #covidbraindamage
How #SARSCoV2 infects/affects brain astrocytes https://pnas.org/doi/10.1073/pnas.2122236119 @PNASNews by @Andrews_MG
@tmturkee
@TheOttolab
@Kriegsteinlab and colleagues
"COVID Brain Problems May Stem From Attack on Endothelial Cells — Findings could have implications for treating long COVID"
UK researchers scanned the brains of 400 people before and after mild covid, compared them with controls and found:
Covid linked to significant brain shrinkage: "Even a mild COVID-19 infection can change the brain. People infected had a greater reduction in brain volume and performed worse on cognitive tests than those who did not contract COVID-19."
![[Long COVID: Pathogenesis and Therapeutic Approach] - PubMed](https://rdl.ink/render/https%3A%2F%2Fcdn.ncbi.nlm.nih.gov%2Fpubmed%2Fpersistent%2Fpubmed-meta-image.png?width=350&height=&ar=16:9&mode=crop&format=avif&dpr=2)
