S41467 022 30932 1
Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19
Covid and Brain Damage
Comprehensive clinical assessment identifies specific neurocognitive deficits in working-age patients with long-COVID
Comprehensive clinical assessment identifies specific neurocognitive deficits in working-age patients with long-COVID
Similarities between Alzheimer’s and long COVID found in new study
New research from Australia: proteins generated by SARSCoV2 can form into aggregations similar to those found in the brains of patients with Alzheimer’s...this mechanism may underpin persistent neurological symptoms such as brain fog seen in long COVID.
The Impact of COVID-19 Infection on Cognitive Function and the Implication for Rehabilitation: A Systematic Review and Meta-Analysis
A new review and meta-analysis finds that #LongCovid substantially impacts cognitive functions but that the effect size depends on the type of function.
You're not imagining 'COVID brain' — here's the latest evidence
COVID cognitive decline more widespread than thought say researchers at Australia's first long-COVID clinic Some sort of cognitive decline was recorded in almost all of the participants, regardless of the severity of the initial infection.
Andrew Ewing on Twitter
Comprehensive thread on Twitter 1/36 Update of the covid and the brain talk I recently gave to Drs at Select Medical Better quality figures More on references to look up: Lancet, NEJM, Nature, Neurology, etc Some new material dispersed and at end Some thoughts on possible treatments (not my expertise)
Rapid vigilance and episodic memory decrements in COVID-19 survivors
Excellent study from Oxford💥💥 This is the first report describing deficits in sustained attention & episodic memory amongst mildly-affected #COVID19 survivors long after the acute illness, in people who were not complaining of long-COVID symptoms
Cognitive impairment from long COVID equivalent to aging 20 years, study finds
"A new study says that cognitive impairment due to long COVID is the equivalent of aging 20 years or losing 10 IQ points."
Covid-19: Long Term Brain Injury
"A series of recent studies document long term brain-damage in as many as one quarter of all those infected regardless of the severity of the initial disease."
Viral respiratory infections and psychosis: A review of the literature and the implications of COVID-19
"Several human coronaviruses (HCoVs) have been associated with psychotic disorders and increasing reports of the neuropsychiatric manifestations of COVID-19 suggest it has neuroinvasive properties similar to those of other HCoVs."
Covid-19 And Parkinson’s Disease Can Be A Dangerous Combination: Expert Tips For Caregivers | TheHealthSite.com
Covid-19 And Parkinson’s Disease Can Be A Dangerous Combination:
The viral disease has affected the brain to quite an extent. The immune response in the brain is what gets affected first and then there is the direct invasion of the coronavirus.
Severe cases of COVID causing cognitive impairment equivalent to ageing 20 years, new study finds
Severe cases of COVID causing cognitive impairment equivalent to ageing 20 years, new study finds
"It is very possible that some of these individuals will never fully recover,"
Tom Andrews on Twitter
Comprehensive thread on Twitter: sleepiness, ophthalmoplegia, Parkinsonism, spontaneous movements, dysuria & constipation which we consider characteristic of lethargic encephalitis, due to the position of the lesions in the brainstem THE OCULAR COMPLICATIONS OF ENCEPHALITIS LETHARGICA
SARS-CoV-2 causes brain inflammation and induces Lewy body formation in macaques
“SARS-CoV-2 causes brain inflammation and Lewy bodies, a hallmark for Parkinson, after an asymptomatic infection in macaques.”
Chris Turnbull on Twitter
Comprehensive thread on Twitter: 1/ Covid New Study Shows bleeding on the brain, neuron death & damage, severe inflammation including the 'mild': cases virus found in cells that line the Brain and brainstem—new insight into Long Covid, strokes and other brain disease
How Effects on the Brain Can Produce Long COVID - Neuroscience News
"Even with mild cases, COVID-19 can cause confusion, delirium, sleepiness, poor cognitive function, intense headaches, and uncomfortable skin sensations. In more severe cases, patients have suffered complications as serious as strokes."
Coronavirus effects linger in once-healthy brains. Long COVID's toll feared in Louisiana.
“‘My great concern is that there could be a wave of dementia cases over the next 5 to 10 years that can be directly traced back to this pandemic…It is a vascular virus…It does bad things to blood vessels in our bodies.’”
Increased incidence of COVID-19 breakthrough cases associated with psychiatric disorders
"In a recent study published in JAMA Network Open, researchers investigated the relationship between past psychiatric disorder diagnoses and breakthrough cases of coronavirus disease 2019 (COVID-19) in fully vaccinated people."
Ene
Some get encephalitis. I think there is a variety of possible causes & potentially these also can differ across the acute/ post acute/ #LongCovid timeline 0-2.5yrs +counting
COVID-19 brain fog | CityNews Toronto
"Bluntly and rather disconcertingly, Pirzada says if someone is dealing with significant brain fog, there isn’t much that can be done...
'We can refer you to a specialist that will see you in the long term, but they won’t know what to do either,'"
The Race to Unravel COVID’s Hidden Link to Alzheimer’s
"In some brains, COVID causes molecular changes that mirror those seen in the brains of people with Alzheimer’s, leading some scientists to believe that long COVID may be an atypical form of the memory-destroying disorder."
COVID-19 brain fog | CityNews Toronto
"Colin Furness, an epidemiologist in Toronto, says that EVERYBODY that gets COVID-19 deals with some brain tissue loss. The question, he says, is how much."
Patients at greater risk of dementia after COVID-19 pneumonia, study finds
Patients hospitalized with COVID-19 pneumonia have a higher risk of being diagnosed with dementia compared to those with other types of pneumonias, according to a new study from the University of Missouri.
Physical, psychological and cognitive profile of post-COVID condition in healthcare workers, Quebec, Canada
"Persistent cognitive and other professionally-disabling sequelae of COVID-19 in essential workers could have critical implications for quality healthcare delivery during and after the pandemic."
Nej mc2033369
Microvascular Injury in the Brains of Patients with Covid-19
David Lee, MD on Twitter
Non-specific white matter hyperintensities on MRI have often been considered benign by most physicians. In this NIH-led study of nine fatal COVID-19 cases, histopathology demonstrated that these punctate areas are indicative of microvascular injury.
laurie allee on Twitter
“This study confirms what we have also seen at Northwestern, that cognitive problems are persistent both in patients who were previously hospitalized and also in patients who had only mild respiratory symptoms,”
Memory loss and 'brain fog' may be side effects of COVID-19, new study shows
Study: Long-term COVID-19 side effects could include memory loss and other cognitive dysfunctions.
Most common cognitive deficits: memory encoding and memory recall, which showed up in 24% and 23% of the participants, respectively.
'They can’t think': Covid patients suffer memory problems months after recovering
"Even younger patients were affected by cognitive impairment and difficulty storing new memories."
Even mild cases of COVID-19 might result in brain shrinkage and impaired cognitive function
"Even mild cases of COVID-19 might result in brain shrinkage and impaired cognitive function"