Covid and Brain Damage

Covid and Brain Damage

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Harry Spoelstra on Twitter
Harry Spoelstra on Twitter

Interesting study: Inflammatory and mental health sequelae of COVID-19

"The COVID-19 pandemic has caused significant negative consequences to mental health. Increased inflammatory factors and neuropsychiatric symptoms, such as cognitive impairment (“brain fog”), depression, and anxiety are associated with long COVID [post-acute sequelae of SARS-CoV-2 infection (PASC), termed neuro-PASC]"

➡️Biomarker: MIG

"Growing evidence supporting the usefulness of circulating MIG(monokine induced by gamma interferon (IFN-γ) aka CXCL9) levels as a biomarker reflecting IFN-γ production, which is important because individuals with neuro-#PASC/ neuro-#Longcovid have elevated IFN-γ responses to internal SARS-CoV-2 proteins"

·twitter.com·
Harry Spoelstra on Twitter
laurie allee on Twitter
laurie allee on Twitter
"This comprehensive analysis of patients with neuro-PASC revealed a disabling but difficult to characterize syndrome that develops even after relatively mild COVID-19. A common feature is memory impairment."
·twitter.com·
laurie allee on Twitter
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
154,000 veterans who had COVID were 1.4 times likelier to have a neurologic condition--memory problems, stroke, neuropathy, mental health disorders, migraines, or seizures--in year following illness. This was true for all COVID cases, from mild to severe.
·alzforum.org·
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
Selective Neuronal Mitochondrial Targeting in SARS-CoV-2 Infection Affects Cognitive Processes to Induce ‘Brain Fog’ and Results in Behavioral Changes that Favor Viral Survival
Selective Neuronal Mitochondrial Targeting in SARS-CoV-2 Infection Affects Cognitive Processes to Induce ‘Brain Fog’ and Results in Behavioral Changes that Favor Viral Survival
"Selective Neuronal Mitochondrial Targeting in SARS-CoV-2 Infection Affects Cognitive Processes to Induce ‘Brain Fog’ and Results in Behavioral Changes that Favor Viral Survival"
·ncbi.nlm.nih.gov·
Selective Neuronal Mitochondrial Targeting in SARS-CoV-2 Infection Affects Cognitive Processes to Induce ‘Brain Fog’ and Results in Behavioral Changes that Favor Viral Survival
Could long covid change brain activity
Could long covid change brain activity
"Scientists report that brain scans of long COVID patients show abnormal activity in areas related to memory...likened the brain changes to what happens in HIV patients and in those with traumatic brain injury."
·usnews.com·
Could long covid change brain activity
Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration? - PubMed
Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration? - PubMed

Related: "Drawing from recent data on prion disease pathogenesis and immune responses to SARS-CoV-2, we hypothesize that the cascade of systemic inflammatory mediators in response to the virus accelerated the pathogenesis of our patient's prion disease."

·pubmed.ncbi.nlm.nih.gov·
Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration? - PubMed
Chris Turnbull on Twitter
Chris Turnbull on Twitter

Comprehensive thread on possible prion involvement with SarsCov2 Mad Cov-Disease? New study looks at the possibility that Covid is a prion (a type of protein that can cause degenerative brain diseases such as Creutzfeldt-Jakob disease (CJD) aka mad Cow disease

Is Long Covid a prion disease?

·twitter.com·
Chris Turnbull on Twitter