“In conclusion, SARS-CoV-2 has a profound and multifaceted impact on cardiac tissue, mediated primarily through the Spike protein's interaction with the ACE2 receptor.”
“The virus not only causes direct damage to the heart by infecting cardiomyocytes but also triggers significant systemic effects that can exacerbate preexisting cardiovascular conditions.”
“The extensive expression of ACE2 in heart cells underpins the high susceptibility of cardiac tissues to SARS-CoV-2, leading to a range of complications from myocarditis to severe myocardial dysfunction.”