“In conclusion, SARS-CoV-2 has a profound and multifaceted impact on cardiac tissue, mediated primarily through the Spike protein's interaction with the ACE2 receptor.”
“The virus not only causes direct damage to the heart by infecting cardiomyocytes but also triggers significant systemic effects that can exacerbate preexisting cardiovascular conditions.”
“The extensive expression of ACE2 in heart cells underpins the high susceptibility of cardiac tissues to SARS-CoV-2, leading to a range of complications from myocarditis to severe myocardial dysfunction.”
“Cardiac injury is recognized as one of the most frequent complications of the disease. Long-term cardiac complications following COVID-19 include ischemic heart disease, heart failure, arrhythmias, and myocarditis.”
➡️“Clinicians and other interprofessional healthcare team members need to maintain a high degree of suspicion for developing these complications, especially since typical symptoms of cardiac disease may not be present in these patients.”