SARS-CoV-2 infection can markedly influence the initiation and progression of atherosclerotic lesions.
Excellent multi-tweet analysis thread of new study:
New paper in PLOS Pathogens has findings about:
Cardiovascular disease and covid-19: A systematic review
❗Cardiovascular complications of COVID-19 are numerous and life-threatening❗
An updated systematic authors review of the literature(2020–2024) only confirming the bad news, its strength.
SARS-CoV-2 can damage cardiac muscle cells (cardiomyocytes). Different variants are found to infect and affect differently cardiomyocytes in a new study in vitro and in vivo(=animal model/Golden hamster). BA.2 Omicron flagged as particularly dangerous
Persistence of SARS-CoV-2 colonization and high expression of inflammatory factors in cardiac tissue 6 months after COVID-19 recovery: a prospective cohort study
“The increase of cardiovascular risk associated with COVID-19 might be extended for years and not limited to the acute phase of the infection. This should promote the planning of longer follow-up for COVID-19 patients to prevent and promptly manage the potential occurrence of major adverse cardiovascular and cerebrovascular events." ➡️ Now add reinfections into the risk equation
Comprehensive Twitter thread: 1/ A fresh, running thread on COVID’s well-documented cardiovascular harms for anyone who needs links when discussing the rise in heart failure and strokes among younger and middle-aged people since 2020:
Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study
8 March 2023
Thread on Twitter: The virus indefinitely strips the blood of a specific group of cells that prevent cardiovascular disease. It’s Latent disease that will kill people. This obsession with the acute phase is myopic and/or nefarious.
A new study in @SciImmunology led by @AnisBarmada & Jon Klein @YaleIBIO with @lucasite_lab
@InciYildirim11
@YalePediatrics teams explored immune signatures of people who developed myocarditis after mRNA vaccines. Here is what we found. 🧵 (1/)
Doctors and researchers are beginning to see connection between COVID surges and heart attacks. @ErinNBCNews and Senior Medical Correspondent for @NBCNews
@DrJohnTorres share more.
For sudden deaths ( @MeetJess ), for young people (eg, 25-44y/o), this paper says there were about 23% to 34% more cardiac deaths than expected during the pandemic. For us older folks, about 13% to 18% more.
She details that prior to the pandemic the average age of referrals to her cardiology clinic was aged 55-80yrs. Now it is 16-40yrs Now at least 50% are long Covid with cardiovascular symptoms.
Even mild Covid infection can harm heart health, study finds
"We were surprised to observe such a decline in vascular health, which deteriorated even further with time since COVID-19 infection,"
From 2022: "New Guidelines Explain How to Manage Post-COVID Heart Problems"
"COVID infections could cause long-term deadly damage to your arteries, a study has shown.
Virus patients’ arteries became increasingly stiffer in the months after they caught it, even if their initial infection was mild, researchers found."
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