CCL2-mediated endothelial injury drives cardiac dysfunction in long COVID
Ongoing cardiac dysfunction in Long Covid is, in part, caused by upregulation of CCL2 by inflamed endothelial cells(thrombotic vascular tissue).
“Cardiac injury is recognized as one of the most frequent complications of the disease. Long-term cardiac complications following COVID-19 include ischemic heart disease, heart failure, arrhythmias, and myocarditis.”
➡️“Clinicians and other interprofessional healthcare team members need to maintain a high degree of suspicion for developing these complications, especially since typical symptoms of cardiac disease may not be present in these patients.”