Covid and Heart Damage
Unraveling the relevance of SARS-Cov-2 infection and ferroptosis within the heart of COVID-19 patients
🔥Important and detailed study on the potential mechanism behind C19 related heart damage!
SARS-CoV-2 infection can markedly influence the initiation and progression of atherosclerotic lesions.
- Endothelial dysfunction, platelet activation, and persistent inflammation are potential drivers of increased atherosclerosis following COVID-19.
Excellent multi-tweet analysis thread of new study:
New paper in PLOS Pathogens has findings about:
- the effect of the SARS-CoV-2 spike protein on cardiac cells (and mitochondrial dysfunction!),
- a treatment to be investigated, and
- how this is NOT caused by mRNA vaccines
Cardiovascular disease and covid-19: A systematic review
❗Cardiovascular complications of COVID-19 are numerous and life-threatening❗
An updated systematic authors review of the literature(2020–2024) only confirming the bad news, its strength.
SARS-CoV-2 can damage cardiac muscle cells (cardiomyocytes). Different variants are found to infect and affect differently cardiomyocytes in a new study in vitro and in vivo(=animal model/Golden hamster). BA.2 Omicron flagged as particularly dangerous
Persistence of SARS-CoV-2 colonization and high expression of inflammatory factors in cardiac tissue 6 months after COVID-19 recovery: a prospective cohort study
“The increase of cardiovascular risk associated with COVID-19 might be extended for years and not limited to the acute phase of the infection. This should promote the planning of longer follow-up for COVID-19 patients to prevent and promptly manage the potential occurrence of major adverse cardiovascular and cerebrovascular events." ➡️ Now add reinfections into the risk equation
Comprehensive Twitter thread: 1/ A fresh, running thread on COVID’s well-documented cardiovascular harms for anyone who needs links when discussing the rise in heart failure and strokes among younger and middle-aged people since 2020:
Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study
8 March 2023
Thread on Twitter: The virus indefinitely strips the blood of a specific group of cells that prevent cardiovascular disease. It’s Latent disease that will kill people. This obsession with the acute phase is myopic and/or nefarious.
A new study in @SciImmunology led by @AnisBarmada & Jon Klein @YaleIBIO with @lucasite_lab
@InciYildirim11
@YalePediatrics teams explored immune signatures of people who developed myocarditis after mRNA vaccines. Here is what we found. 🧵 (1/)
Doctors and researchers are beginning to see connection between COVID surges and heart attacks. @ErinNBCNews and Senior Medical Correspondent for @NBCNews
@DrJohnTorres share more.