Covid can cause heart problems. Here's how the virus may do its damage.
"Covid can cause damage to the heart on a cellular level that can lead to lasting problems, including irregular heartbeats and heart failure, preliminary research suggests."
Covid and Heart Damage
Eric Topol on Twitter
The persistent excess of cardiovascular deaths in the United States through the 1st 2 years of the pandemic, consistent throughout 5 Covid waves, even well after surges in cases waned
Heart attacks and strokes late after Covid
"Covid is associated with an excess of heart attacks and strokes beyond the first month of infection. That can no longer be ignored or refuted."
How COVID-19 permanently damages the heart
"...the ongoing inflammation in COVID-19 attacks the heart tissue and, in the long term, remodels the smallest coronary vessels by directing special precursor cells of the immune system from the blood into the heart."
The SARS-CoV-2 Spike protein induces long-term transcriptional perturbations of mitochondrial metabolic genes, causes cardiac fibrosis, and reduces myocardial contractile in obese mice
New preprint of mouse study: "The SARS-CoV-2 Spike protein induces long-term transcriptional perturbations of mitochondrial metabolic genes, causes cardiac fibrosis, and reduces myocardial contractile in obese mice"
Mid- and Long-Term Atrio-Ventricular Functional Changes in Children after Recovery from COVID-19
"Mid- and Long-Term Atrio-Ventricular Functional Changes in Children after Recovery from COVID-19"
Inflammation and vascular remodeling in COVID-19 hearts
"We conclude that cardiac involvement in COVID-19 is an angiocentric macrophage-driven inflammatory process, distinct from classical anti-viral inflammatory responses, and substantially underappreciated by conventional histopathologic analysis."
COVID-19 Surges Linked to Spike in Heart Attacks
“The dramatic rise in heart attacks during the pandemic has reversed what was a prior decadelong steady improvement in cardiac deaths,”
John Hess MD on Twitter
POST infection cardiovascular events are still occurring at significant rates. Even in the young AND with "mild" Omicron. Excess deaths in the USA have shown this for the ENTIRE pandemic (including pre-vaccine).
Rise in sudden deaths among young people with “mild” COVID-19 points to urgent need to end the pandemic
"There is an increase in sudden deaths from heart attacks and strokes among young people infected with what the Centers for Disease Control and Prevention (CDC) refers to as 'mild' cases of COVID-19."
Heart attack deaths jumped sharply among young US adults in 2nd year of COVID pandemic | Chattanooga Times Free Press
"While other infections such as the flu are known to lead to a slightly increased risk of heart attacks, the Cedars-Sinai researchers said, they could find nothing that compared with the jump in deaths linked to the COVID-19 pandemic"
New evidence that heart damage risk is much higher after COVID-19 infection than after vaccination
"Patients are seven times more likely to develop myocarditis after a COVID-19 infection than after receiving a COVID-19 vaccine, according to a new meta-analysis published in Frontiers in Cardiovascular Medicine."
Lingering cardiac involvement in previously well people after mild COVID-19
"Serial heart MRI scans conducted in previously well people with mild initial COVID-19 illness suggest that lingering cardiac symptoms may be explained, at least in part, by ongoing mild cardiac inflammation."
Cardiac inflammation after mild COVID-19 in previously healthy people
"...people with mild COVID-19 showed rare signs of cardiac damage, wherein the cardiac symptoms were profound... non-ischemic cardiac inflammatory changes have been observed previously in populations comprising young athletic people following COVID-19"
COVID Attacks DNA in Heart, Unlike Flu, Study Says
"COVID-19 causes DNA damage to the heart, affecting the body in a completely different way than the flu does, according to a recent study published in Immunology"
Unlike flu, COVID-19 attacks DNA in the heart: new research
"Unlike flu, COVID-19 attacks DNA in the heart: new research:"
‘Prevalence of youth suffering heart attacks goes up post-Covid’
"The prevalence of young patients with heart attacks has increased post-Covid...even if the person feels that he has recovered, he may not realise that the virus causes some changes in the endothelium that can cause heart attack & stroke."
SARS-CoV-2 Nsp6 causes cardiac defects through MGA/MAX complex-mediated increased glycolysis
"The presence of virus in cardiac tissue of patients with COVID-19 suggests this is a direct, rather than secondary, effect of infection."
Three myths about COVID-19 — and the biggest challenge that lies ahead
"COVID-19 left me with a serious heart complication that occurs in 2 per cent of infected people, with the risk not diminished by immunisation or prior infection."
Dr Elisa Perego on Twitter
Twitter thread by Dr. Elisa Perego Evidence of cardiac involvement in a significant percentage of covid survivors, even with "mild" disease from Puntmann et al 2020
"cardiac MRI revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%)
Lingering cardiac involvement in previously well people after mild COVID-19
Lingering cardiac involvement in previously well people after mild COVID-19
Roland Baker on Twitter
(1/n) Nature: Lingering cardiac involvement in previously well people after mild COVID-19: persistent subclinical cardiovascular inflammation seems to predispose people to a poor prognosis and the development of heart failure.
COVID-19’s Lingering Toll On The Heart
"research is revealing more about the longterm consequences of even one infection with the SARS-CoV2 virus...finding long-lasting signs of heart disorders in the majority of recovered patients in their study group–even up to nearly a year later."
Raina MacIntyre 😷💉💉💉💉 on Twitter
People with mild COVID can develop shortness of breath and palpitations post-COVID, and this may be due to inflammation of the heart.
Study Finds Increased Heart Disease, Stroke Risk After Surviving Even Mild Covid-19
After Covid: 63% higher likelihood of heart attack 72% higher likelihood of heart failure 145% higher likelihood of cardiac arrest. atrial fibrillation (71% more likely), sinus tachycardia (84%) sinus bradycardia (53%) ventricular arrhythmias (84%).
Eric Topol on Twitter
"The imaging findings suggest that inflammatory cardiac involvement after COVID may be a pathophysiological commonality shared among all individuals, regardless of the expression of cardiac symptoms"
COVID-19 diagnosis raises risk of heart attack, stroke - Harvard Health
“In the week after a COVID-19 diagnosis, the risk of a first heart attack increased by three to eight times. The risk of a first stroke caused by a blood clot multiplied by three to six times.”
Long-term cardiovascular outcomes of COVID-19
“beyond the first 30 d after infection…increased risk of incident cardiovascular disease…including cerebrovascular disorders, dysrhythmias, ischemic and non-ischemic heart disease, pericarditis, myocarditis, heart failure and thromboembolic disease.“
Prof. Christina Pagel on Twitter
good overview of what we know - and don't know - about increased risk of heart problems after covid
Coronavirus spike protein activated natural immune response, damaged heart muscle cells
Multiple ways SarsCov2 damages the heart, not found in other coronaviruses, colds or flu: