"SARS-CoV-2 has been shown to infect the male reproductive tract.. Autopsy studies of COVID-19 patients have revealed testicular inflammation, leukocyte infiltration, and impaired Leydig cell function. SARS-CoV-2 may also fragment sperm DNA, reducing fertilization potential.. [In addition,] SARS-CoV-2 may affect the epididymis, a critical site for sperm maturation. Inflammation and oxidative stress in the epididymis can impair sperm motility and viability.."

“SARS-CoV-2 enters Leydig cells via the ACE2 receptor, highly expressed in both mouse and human testes. Once inside, the virus hijacks the metabolic machinery for its own replication.”