Frontiers | SARS-CoV-2 exploits steroidogenic machinery, triggers lipid metabolism for viral replication and induces immune response in Leydig cells of K18-hACE2 mice
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“SARS-CoV-2 enters Leydig cells via the ACE2 receptor, highly expressed in both mouse and human testes. Once inside, the virus hijacks the metabolic machinery for its own replication.”