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SARS-CoV-2 impairs male fertility by targeting semen quality and testosterone level: A systematic review and meta-analysis | PLOS ONE
SARS-CoV-2 impairs male fertility by targeting semen quality and testosterone level: A systematic review and meta-analysis | PLOS ONE

“The present study demonstrated that SARS-CoV-2 significantly reduced ejaculate volume, sperm count, concentration, viability, normal morphology, and total and progressive motility. Furthermore, SARS-CoV-2 led to a reduction in circulating testosterone level, but a rise in oestrogen, prolactin, and luteinizing hormone levels. These findings were associated with a decline in testosterone/luteinizing hormone ratio. Conclusions The current study provides compelling evidence that SARS-CoV-2 may lower male fertility”

The present study demonstrated that SARS-CoV-2 significantly reduced ejaculate volume, sperm count, concentration, viability, normal morphology, and total and progressive motility. Furthermore, SARS-CoV-2 led to a reduction in circulating testosterone level, but a rise in oestrogen, prolactin, and luteinizing hormone levels. These findings were associated with a decline in testosterone/luteinizing hormone ratio. Conclusions The current study provides compelling evidence that SARS-CoV-2 may lower male fertility
·journals.plos.org·
SARS-CoV-2 impairs male fertility by targeting semen quality and testosterone level: A systematic review and meta-analysis | PLOS ONE
Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test
Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test
"couples with a desire for pregnancy should be warned that sperm quality after COVID-19 infection can be suboptimal. The estimated recovery time is 3 months...follow-up studies are under way to confirm this and to determine if permanent damage occurred..."
·sciencedirect.com·
Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test
Jmv
Jmv
"New study: Men infected with COVID have one third less sperm compared to uninfected men over 3 months later. Of 100 men infected and not hospitalized four had no viable sperm. Of 100 men not infected, none had this condition."
·onlinelibrary.wiley.com·
Jmv
Tom Andrews on Twitter
Tom Andrews on Twitter

Analysis of study thread on Twitter: "We investigated testicular alterations in deceased COVID-19-patients, the precise location of the virus, its replicative activity, and the molecules involved in the pathogenesis." 1/x

·twitter.com·
Tom Andrews on Twitter
Tom Andrews on Twitter
Tom Andrews on Twitter
"Scientists from Nanjing Medical University and Suzhou Hospital lead by Dr Jianqing Wang.. say that males affected by the SARS-Cov2 coronavirus which causes the Covid-19 disease will likely become infertile even if they recover"
·twitter.com·
Tom Andrews on Twitter
Testicular Atrophy and Hypothalamic Pathology in COVID-19: Possibility of the Incidence of Male Infertility and HPG Axis Abnormalities
Testicular Atrophy and Hypothalamic Pathology in COVID-19: Possibility of the Incidence of Male Infertility and HPG Axis Abnormalities
"key reports on testicular abnormalities and pathological signatures in the hypothalamus of COVID-19 patients...testicular pathology resulting from inflammation and oxidative stress might lead to infertility in a significant portion of COVID-19 survivors."
·link.springer.com·
Testicular Atrophy and Hypothalamic Pathology in COVID-19: Possibility of the Incidence of Male Infertility and HPG Axis Abnormalities