Long COVID syndrome in children: neutrophilic granulocyte dysfunction and its correlation with disease severity.
Neutrophil Long COVID syndrome in children: neutrophilic granulocyte dysfunction and its correlation with disease severity.
“CogIt started when my brain gave out on me in algebra class one January day in 2022. I couldn’t figure out a simple math problem; all I saw were numbers and symbols. My eyelids drooped, my head hurt, I could barely stay awake. Something wasn’t right. I hadn’t felt like myself since getting COVID-19 a couple weeks earlier. Simple tasks like reading a text or standing up were draining. But what happened in that classroom scared me. At age 14, my life became a state of constant exhaustion, punctuated by doctors’ visits that, months later, would lead to a Long COVID diagnosis.”
“New-onset psychiatric symptoms directly related to SARS-CoV-2 virus infection are not rare phenomena among pediatric patients. CSF tests support the presence of central immune responses in some patients.
Our patients developed psychiatric symptoms within 2 weeks of virus infection. In a small portion of patients (2/10, 20%), positive findings in CSF (cerebro-spinal fluid) suggest intracranial immune response and disruption of the blood–brain barrier (BBB).. EEG showed epileptic wave in one child (1/9, 11%) and slow background rhythm or slow wave activities in five children (5/9, 55%).. [Among six children whose cytokine levels in CSF were measured,] one-third (2/6, 33.3%) had increased IL-8 levels, which indicates IL-8 in the central nervous system may be involved in the mechanisms of SARS-CoV-2 virus-induced psychiatric symptoms. Increased IL-8 levels in CSF have been reported in brain infection and head injury.. We also detected elevated IgG level, albumin quotient, and positive oligoclonal band in the CSF in another two children, which supports the disrupted blood–brain barrier and central autoimmune reaction theory."
“My 7 year old niece, who contracted Covid 4x during the last school year, no longer knows her cousin (my daughter) nor her Granddad.
A few days before her last infection she told my Mom how much she misses Granddad and how he would give her everything!
The week before her last infection she Facetime my daughter and I to recite her Bible verse for the week.
Then she got Covid, started losing things, has problems with word finding, and obvious memory loss.
This happened in May.
My SIL can’t get her in to see a Neurologist until November because all appointments are taken.
Is this the government AND the citizens of this country have decided is ok?”
There is a physical change in the brain’ in children with neurological damage from COVID.
In Data From 96 Studies
“Our findings reveal that a substantial proportion of pediatric COVID-19 patients with neurological symptoms exhibit abnormal neuroimaging findings, with 43.74 percent of children in the included studies demonstrating such abnormalities,”
Thread Previously healthy and fit children with 'high social and academic performance' found to have brains that show classic signs of severe neurogenerative diseases such as Alzheimer's dementia as well as a significant drop in memory and intelligence after 'mild' Covid
Thread Unusual brain abscess in children under 18 have risen to new height.
These abscesses usually follow a respiratory infection like including COVID-19
https://sciencealert.com/abnormal-surge-of-brain-abscesses-in-american-children-cdc-says
Thread New study documents the case of two previously healthy sisters - 11 and 13-years-old - with new-onset cognitive decline after mild covid. The ability of their brains to consume glucose had been impaired - an initiating factor for dementia, Parkinson's and Alzheimer's disease 🧵
Thread New study documents covid-triggered brain inflammation resulting in the death of a previously healthy 9 year-old girl. From the doubled chance of type 1 diabetes, to brain damage and death, will the mass media ever report on the harm to children from repeat covid infections?
High levels of gliosis occur in the neonatal brain within a week after in utero infection, and macrosomia is seen in infected pups. COVID-19 infection in pregnant hACE2-KI mice replicates infection severity and effects seen in pregnant women.
Kids #COVID19: 22% had neurologic involvement. 9% had life-threatening conditions, with half having acute central nervous system (CNS) infections or demyelination; 43% died or had new neurologic deficits. #Notacold https://ja.ma/3EpMDUm via @JAMANeuro part of @JAMANetwork
Thread COVID-19: Pediatric Diabetes, Lung Damage, Brain Impact, Newborns, and Higher Hospitalization Rates
Studies show kids are also at risk of long-term consequences from infection and especially those <5 for higher rates of hospitalization than most adults. Let's take a look.🧵1/
Children who got COVID-19 had increased risks of cognitive deficit, insomnia, intracranial haemorrhage, ischaemic stroke, nerve root & plexus disorders, psychotic disorders, and epilepsy or seizures (HRs: 1·20 to 2·16)."
COVID-19 is not flu, certainly.
"Covid-19 can severely damage your child's brain.
The research identifies a wide spectrum of neurological complications in children and suggests they may be more common than in adults admitted with Covid-19."
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