Covid and Liver Damage

Covid and Liver Damage

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Related: Coronavirus disease 2019 (COVID-19) is associated with a significant morbidity and mortality in patients with cirrhosis. There is a significantly higher morbidity and mortality due to COVID-19 in patients with decompensated cirrhosis as compared to compensated cirrhosis, and in patients with cirrhosis as compared to noncirrhotic chronic liver disease.

#Liver#cirrhosis
·jcehepatology.com·
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Liver injury due to coronavirus disease 2019 (COVID-19) is being increasingly recognized. Abnormal liver chemistry tests of varying severities occur in a majority of patients. However, there is a dearth of accompanying liver histologic studies in these patients.
#Liver
·cmghjournal.org·
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COVID 19 and liver: An A–Z literature review
#Liver
·dldjournalonline.com·
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COVID-19 and liver disease: mechanistic and clinical perspectives
COVID-19 and liver disease: mechanistic and clinical perspectives
Our understanding of the hepatic consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its resultant coronavirus disease 2019 (COVID-19) has evolved rapidly since the onset of the pandemic. In this Review, we discuss the hepatotropism of SARS-CoV-2, including the differential expression of viral receptors on liver cell types, and we describe the liver histology features present in patients with COVID-19.
#Liver
·nature.com·
COVID-19 and liver disease: mechanistic and clinical perspectives
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Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens
#Liver
·thelancet.com·
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Liver Injury in Patients Hospitalized for COVID-19: Possible Role of Therapy
Liver Injury in Patients Hospitalized for COVID-19: Possible Role of Therapy
Patients with COVID-19 show a high prevalence of liver injury. The pattern of this liver damage is still not fully understood. Different etiopathogenetic factors may concur; from a direct cytopathic effect, once the virus binds to the ACE-2 receptors, to the immune-mediated collateral damage, due to cytokine storm.
#Liver
·mdpi.com·
Liver Injury in Patients Hospitalized for COVID-19: Possible Role of Therapy
Infection of liver hepatocytes with SARS-CoV-2
Infection of liver hepatocytes with SARS-CoV-2
"in people without underlying liver disease who contract COVID-19, abnormally high levels of liver enzymes are commonly observed and have been associated with an increase in subsequent intensive care unit admission, mechanical ventilation and death"
#Liver
·nature.com·
Infection of liver hepatocytes with SARS-CoV-2
laurie allee on Twitter
laurie allee on Twitter
"Covid-19 induced hepatitis (CIH), definition and diagnostic criteria of a poorly understood new clinical syndrome"
#Liver#hepatitis
·twitter.com·
laurie allee on Twitter
Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality - PubMed
Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality - PubMed

Covid and Hepatitis C: "...history of HCV infection leads to an accentuated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virulence, irrespective of baseline comorbidities, admission laboratory variables, or COVID-19-induced liver injury"

#Liver#hepatitis
·pubmed.ncbi.nlm.nih.gov·
Chronic hepatitis-C infection in COVID-19 patients is associated with in-hospital mortality - PubMed
Pmc7927974
Pmc7927974
Case study: COVID-19 infection with hepatitis B co-infection "fever, catarrh, headaches, fatigue, and loss of smell...history of chronic hepatitis B infection which appeared to be inactive given a history of normal outpatient liver tests prior to Covid..."
#Liver#hepatitis
·ncbi.nlm.nih.gov·
Pmc7927974
Liver injury in COVID-19: Known and unknown
Liver injury in COVID-19: Known and unknown
"This review describes the causes of liver injury in patients with coronavirus disease 2019 (COVID-19), including inflammatory storms, hypoxia, drug factors, and viral damage to liver cells, and discusses the treatment of liver injury with COVID-19,"
#Liver
·ncbi.nlm.nih.gov·
Liver injury in COVID-19: Known and unknown