Editorial: What worrying asthma figures tell us about us as a society
“Data released last week shows the number of New Zealanders hampered by asthma or serious lung disease has grown by more than 40% in three years.”
Covid and Lung Damage
Bovhyaluronidase azoximer for long-term pulmonary sequelae of COVID-19: a randomized, double-blind, placebo-controlled trial
bovhyaluronidase azoximer improved exercise tolerance and reduced breathlessness in post-COVID-19 patients.
Faster lung recovery was noted in those with cardiovascular issues after 180 days.
Researchers Shed Light on Cause of 'Happy Hypoxia' in COVID-19 Patients
Researchers Shed Light on Cause of 'Happy Hypoxia' in COVID-19 Patients
Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."
“Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."
Yes. I'm going round to drop off an oximeter. 😟”
Expression of antigen-presenting cells in lung of postmortem SARS-CoV-2 cases | Cellular and Molecular Biology
“Postmortem examination of the lung is a useful tool for understanding the immunopathogenesis of this virus.”
Postmortem examination of the lung is a useful tool for understanding the immunopathogenesis of this virus.
Long-COVID Patients Show Abnormal Lung Perfusion Despite Normal CTs
Patients With Long-COVID Show Abnormal Lung Perfusion Despite Normal CT Scans.
Findings showed elevated angiotensin-converting enzyme & antiphospholipid antibodies. The patients are young healthy female nonsmokers. This isn't what you'd expect to see.
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)
🤔Nice study, but they forgot to look at the Phrenic/Vagus nerve, the latter especially being a well-known Sars2 target, that could explain a lot here. Nonetheless important findings!
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors
“We identified that 69.5% of patients had diaphragm atrophy and 6.5% had diaphragm paralysis…
…The percentage of atrophy was not related to age, gender, BMI, oxygen therapy usage during the COVID-19 infection course, and disease severity."
Arthritis medications could reverse COVID lung damage
“Arthritis drugs already available for prescription have the potential to halt lingering lung problems that can last months or years after COVID-19 infections, new research from the University of Virginia School of Medicine and Cedars-Sinai suggests.
By examining damaged human lungs and developing an innovative new lab model, the scientists identified faulty immune processes responsible for the ongoing lung issues that plague an increasing number of people after they've otherwise recovered from COVID-19. These lasting harms of COVID infection, known as ‘post-infection lung fibrosis,’ have no good treatments. The new research, however, suggests that existing drugs such as baricitinib and anakinra can disrupt the malfunctioning immune response and finally allow damaged lungs to heal.”
Arthritis drugs already available for prescription have the potential to halt lingering lung problems that can last months or years after COVID-19 infections, new research from the University of Virginia School of Medicine and Cedars-Sinai suggests.
By examining damaged human lungs and developing an innovative new lab model, the scientists identified faulty immune processes responsible for the ongoing lung issues that plague an increasing number of people after they've otherwise recovered from COVID-19. These lasting harms of COVID infection, known as "post-infection lung fibrosis," have no good treatments. The new research, however, suggests that existing drugs such as baricitinib and anakinra can disrupt the malfunctioning immune response and finally allow damaged lungs to heal.
Adult-Onset Asthma Induced by COVID-19: A Case Report
The Long Covid spectrum has a new additional presentation: ADULT-ONSET ASTHMA
“This case report presents an instance of adult-onset asthma following a mildly symptomatic SARS-CoV-2 infection in a previously healthy 24-year-old female….Clinicians should be vigilant in monitoring patients recovering from COVID-19, especially those with persistent respiratory symptoms, for the development of asthma."
This is heartbreaking. Noah Lyles has asthma and is at higher risk for severe COVID. They had no preventative measures & let him race & collapse while sick with COVID. Lives & careers are being put at risk because governments & institutions insist on pretending COVID is over.
Pulmonary and renal long COVID at two-year revisit
Study finds 17.8% of COVID patients have lung issues and 23.9% have kidney issues two years post-infection.
Early data predicts these long-term effects with high accuracy.
Longitudinal analysis of the lung proteome reveals persistent repair months after mild to moderate COVID-19
After mild to moderate Covid, the inflamed lung undergoes prolonged repair > 1 year even though chest X-ray and clinical symptoms may have resolved
Zero /dd on Twitter / X
“My lungs aged 19 years after having COVID.
After 18 months and numerous interventions, my lungs still have not regained full capacity.
- In 2021, my lung capacity was age 26.
- By Nov 2022, after getting covid, my lung capacity was age 45.
- Now 2024, my lung capacity is age 37.
My covid symptoms were very mild and lasted only 3 days. Lung therapies below.”
Pulmonary Function and Long-Term Respiratory Symptoms in Children and Adolescents After COVID-19
Pulmonary Function and Long-Term Respiratory Symptoms in Children and Adolescents After COVID-19
Lung perfusion assessment in children with long‐COVID: A pilot study
Lung perfusion assessment in children with long-COVID: A pilot study
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection
Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection
COVID-19 symptoms can linger for months in people with PAH, CTEPH...
“Long COVID syndrome can be common among people with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), affecting more than 60% of patients infected with the SARS-CoV-2 virus in a study from Poland.”
Post-COVID-19 Pulmonary Fibrosis: Facts—Challenges and Futures: A Narrative Review
"Post-COVID-19 Pulmonary Fibrosis: Facts—Challenges and Futures: A Narrative Review"
Chris Turnbull on Twitter
Horrific: Covid double lung transplant:
'This is terrible looking lungs my god look it's like a bomb'
Chris Turnbull on Twitter
'Alarming' asymptomatic 'silent' & 'mild' Covid found to cause severe progressive lung scarring (fibrosis:) that unlike other lung fibrosis that 'usually occurs in the elderly, post-COVID fibrosis is seen irrespective of age and other co-morbidities', shows new study.
A silent march-Post covid fibrosis in asymptomatics – A cause for concern?
significant proportion of patients with asymptomatic to mild COVID-19 cases have demonstrated ground-glass opacities and pneumonia on HRCT.7 However, the impact on lung function over medium to long term and silent progression to fibrosis remains unclear"
25% of COVID-19 patients have lasting reduction in lung function
"25% of COVID-19 patients have lasting reduction in lung function"
Long Covid: Hidden lung damage spotted on scans
"Long Covid: Hidden lung damage spotted on scans"
Dr Graham Lloyd-Jones on Twitter
Not new but this study neatly illustrates the vascular nature of acute #COVID lung disease.
The image shows small blood vessels (red) at the edges of the lungs are shut down & bigger vessels (blue) in the central lungs are enlarged.
#COVIDISNOTPNEUMONIA
Assessment of Small Pulmonary Blood Vessels in COVID-19 Patients Using HRCT
Assessment of Small Pulmonary Blood Vessels in COVID-19 Patients Using HRCT
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae
Lasting Lung Damage Seen in Children and Teens after COVID
"Children and adolescents who have either recovered from COVID-19 or have long COVID show persistent lung damage on MRI, according to a study published in Radiology"
Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography - PubMed
Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography