Covid and Lung Damage

Covid and Lung Damage

32 bookmarks
Custom sorting
A new phenotype of patients with post-COVID-19 condition is characterised by a pattern of complex ventilatory dysfunction, neuromuscular disturbance and fatigue symptoms
A new phenotype of patients with post-COVID-19 condition is characterised by a pattern of complex ventilatory dysfunction, neuromuscular disturbance and fatigue symptoms
“Dyspnoea in PCF is characterised by reduced respiratory muscle strength and complex ventilatory dysfunction indicating neuromuscular disturbance as a distinct phenotype among patients with post-COVID-19 condition. These observations could be a starting point for developing personalised rehabilitation concepts.”
Dyspnoea in PCF is characterised by reduced respiratory muscle strength and complex ventilatory dysfunction indicating neuromuscular disturbance as a distinct phenotype among patients with post-COVID-19 condition. These observations could be a starting point for developing personalised rehabilitation concepts.
·openres.ersjournals.com·
A new phenotype of patients with post-COVID-19 condition is characterised by a pattern of complex ventilatory dysfunction, neuromuscular disturbance and fatigue symptoms
Bovhyaluronidase azoximer for long-term pulmonary sequelae of COVID-19: a randomized, double-blind, placebo-controlled trial
Bovhyaluronidase azoximer for long-term pulmonary sequelae of COVID-19: a randomized, double-blind, placebo-controlled trial

bovhyaluronidase azoximer improved exercise tolerance and reduced breathlessness in post-COVID-19 patients.

Faster lung recovery was noted in those with cardiovascular issues after 180 days.

·medrxiv.org·
Bovhyaluronidase azoximer for long-term pulmonary sequelae of COVID-19: a randomized, double-blind, placebo-controlled trial
Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."
Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."

“Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."

Yes. I'm going round to drop off an oximeter. 😟”

·x.com·
Just on the phone to someone who tested positive for Covid this morning and they say "actually, I'm feeling great, I'm sweating lots and I was really tired, but now I'm just feeling really happy and a little bit breathless but I don't care about anything any more..."
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)

Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)

🤔Nice study, but they forgot to look at the Phrenic/Vagus nerve, the latter especially being a well-known Sars2 target, that could explain a lot here. Nonetheless important findings!

·x.com·
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors ( LC!)
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors

“We identified that 69.5% of patients had diaphragm atrophy and 6.5% had diaphragm paralysis…

…The percentage of atrophy was not related to age, gender, BMI, oxygen therapy usage during the COVID-19 infection course, and disease severity."

·mdpi.com·
Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors
Arthritis medications could reverse COVID lung damage
Arthritis medications could reverse COVID lung damage

“Arthritis drugs already available for prescription have the potential to halt lingering lung problems that can last months or years after COVID-19 infections, new research from the University of Virginia School of Medicine and Cedars-Sinai suggests.

By examining damaged human lungs and developing an innovative new lab model, the scientists identified faulty immune processes responsible for the ongoing lung issues that plague an increasing number of people after they've otherwise recovered from COVID-19. These lasting harms of COVID infection, known as ‘post-infection lung fibrosis,’ have no good treatments. The new research, however, suggests that existing drugs such as baricitinib and anakinra can disrupt the malfunctioning immune response and finally allow damaged lungs to heal.”

Arthritis drugs already available for prescription have the potential to halt lingering lung problems that can last months or years after COVID-19 infections, new research from the University of Virginia School of Medicine and Cedars-Sinai suggests. By examining damaged human lungs and developing an innovative new lab model, the scientists identified faulty immune processes responsible for the ongoing lung issues that plague an increasing number of people after they've otherwise recovered from COVID-19. These lasting harms of COVID infection, known as "post-infection lung fibrosis," have no good treatments. The new research, however, suggests that existing drugs such as baricitinib and anakinra can disrupt the malfunctioning immune response and finally allow damaged lungs to heal.
·news-medical.net·
Arthritis medications could reverse COVID lung damage
Adult-Onset Asthma Induced by COVID-19: A Case Report
Adult-Onset Asthma Induced by COVID-19: A Case Report

The Long Covid spectrum has a new additional presentation: ADULT-ONSET ASTHMA

“This case report presents an instance of adult-onset asthma following a mildly symptomatic SARS-CoV-2 infection in a previously healthy 24-year-old female….Clinicians should be vigilant in monitoring patients recovering from COVID-19, especially those with persistent respiratory symptoms, for the development of asthma."

·cell.com·
Adult-Onset Asthma Induced by COVID-19: A Case Report
This is heartbreaking. Noah Lyles has asthma and is at higher risk for severe COVID. They had no preventative measures & let him race & collapse while sick with COVID. Lives & careers are being put at risk because governments & institutions insist on pretending COVID is over.
This is heartbreaking. Noah Lyles has asthma and is at higher risk for severe COVID. They had no preventative measures & let him race & collapse while sick with COVID. Lives & careers are being put at risk because governments & institutions insist on pretending COVID is over.
·x.com·
This is heartbreaking. Noah Lyles has asthma and is at higher risk for severe COVID. They had no preventative measures & let him race & collapse while sick with COVID. Lives & careers are being put at risk because governments & institutions insist on pretending COVID is over.
Zero /dd on Twitter / X
Zero /dd on Twitter / X

“My lungs aged 19 years after having COVID.

After 18 months and numerous interventions, my lungs still have not regained full capacity.

  • In 2021, my lung capacity was age 26.
  • By Nov 2022, after getting covid, my lung capacity was age 45.
  • Now 2024, my lung capacity is age 37.

My covid symptoms were very mild and lasted only 3 days. Lung therapies below.”

·x.com·
Zero /dd on Twitter / X
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
·mdpi.com·
Long-Term Effect of COVID-19 on Lung Imaging and Function, Cardiorespiratory Symptoms, Fatigue, Exercise Capacity, and Functional Capacity in Children and Adolescents: A Systematic Review and Meta-Analysis
COVID-19 symptoms can linger for months in people with PAH, CTEPH...
COVID-19 symptoms can linger for months in people with PAH, CTEPH...
“Long COVID syndrome can be common among people with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), affecting more than 60% of patients infected with the SARS-CoV-2 virus in a study from Poland.”
·pulmonaryhypertensionnews.com·
COVID-19 symptoms can linger for months in people with PAH, CTEPH...
Chris Turnbull on Twitter
Chris Turnbull on Twitter
'Alarming' asymptomatic 'silent' & 'mild' Covid found to cause severe progressive lung scarring (fibrosis:) that unlike other lung fibrosis that 'usually occurs in the elderly, post-COVID fibrosis is seen irrespective of age and other co-morbidities', shows new study.
·twitter.com·
Chris Turnbull on Twitter
Dr Graham Lloyd-Jones on Twitter
Dr Graham Lloyd-Jones on Twitter

Not new but this study neatly illustrates the vascular nature of acute #COVID lung disease.

The image shows small blood vessels (red) at the edges of the lungs are shut down & bigger vessels (blue) in the central lungs are enlarged.

#COVIDISNOTPNEUMONIA

·twitter.com·
Dr Graham Lloyd-Jones on Twitter